{
  "id": 20446,
  "label": "adrenal medulla neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021237",
  "properties": {
    "xrefs": [
      "GARD:0025301",
      "MEDGEN:108572",
      "NCIT:C4856",
      "UMLS:C0596046"
    ],
    "synonyms": [
      "adrenal medulla neoplasm (disease)",
      "adrenal medulla tumor",
      "adrenal medulla tumour",
      "neoplasm of adrenal medulla",
      "tumor of adrenal medulla",
      "tumour of adrenal medulla"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A neoplasm (disease) that involves the adrenal medulla."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 20437,
      "label": "adrenal gland neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4223,
        7151
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003850",
          "GARD:0019765",
          "MEDGEN:1352",
          "NCIT:C2859",
          "ONCOTREE:ADRENAL_GLAND",
          "Orphanet:100091",
          "UMLS:C0001624"
        ],
        "synonyms": [
          "adrenal gland neoplasm (disease)",
          "adrenal gland tumor",
          "adrenal gland tumour",
          "adrenal neoplasm",
          "adrenal neoplasms",
          "adrenal tumor",
          "adrenal tumour",
          "neoplasm of adrenal gland",
          "neoplasm of the adrenal gland",
          "tumor of adrenal gland",
          "tumor of the adrenal gland",
          "tumour of adrenal gland",
          "tumour of the adrenal gland",
          "ADRENAL_GLAND",
          "adrenal/paraganglial tumor",
          "adrenal/paraganglial tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the adrenal gland."
      },
      "child_count": 16,
      "reference_id": "MONDO:0021227"
    }
  ],
  "children": [
    {
      "id": 5499,
      "label": "adrenal medulla cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4843,
        20446
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5719",
          "GARD:0005755",
          "MEDGEN:87485",
          "NCIT:C4396",
          "SCTID:371965009",
          "UMLS:C0344456",
          "icd11.foundation:1603907778"
        ],
        "synonyms": [
          "adrenal medulla neoplasm",
          "adrenal medulla tumor",
          "adrenal medulla tumour",
          "adrenal medulla cancer",
          "cancer of adrenal medulla",
          "malignant adrenal medulla neoplasm",
          "malignant adrenal medulla tumor",
          "malignant adrenal medulla tumour",
          "malignant neoplasm of adrenal medulla",
          "malignant neoplasm of the adrenal medulla",
          "malignant tumor of adrenal medulla",
          "malignant tumor of the adrenal medulla",
          "malignant tumour of adrenal medulla",
          "malignant tumour of the adrenal medulla"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the adrenal medulla"
      },
      "child_count": 4,
      "reference_id": "MONDO:0003606"
    },
    {
      "id": 6716,
      "label": "adrenal gland pheochromocytoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20313,
        20446
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050892",
          "EFO:0000239",
          "GARD:0024140",
          "ICDO:8700/0",
          "MEDGEN:1636437",
          "NANDO:2200078",
          "NCIT:C3326",
          "UMLS:C4551683"
        ],
        "synonyms": [
          "pheochromocytoma",
          "Intraadrenal paraganglioma",
          "PCC",
          "adrenal gland Chromaffinoma",
          "adrenal gland chromaffin paraganglioma",
          "adrenal gland paraganglioma",
          "adrenal gland pheochromocytoma",
          "adrenal medullary paraganglioma",
          "adrenal medullary pheochromocytoma",
          "adrenal pheochromocytoma",
          "chromaffin paraganglioma of the adrenal gland",
          "pheochromocytoma (adrenal)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neuroendocrine neoplasm of the sympathetic nervous system that secretes catecholamines. It arises from the chromaffin cells of the adrenal medulla. Clinical presentation includes headaches, palpitations, chest and abdominal pain, hypertension, fever, and tremor. Microscopically, a characteristic nesting (zellballen) growth pattern is usually seen. Other growth patterns including trabecular pattern may also be present."
      },
      "child_count": 6,
      "reference_id": "MONDO:0004974"
    },
    {
      "id": 20589,
      "label": "benign neoplasm of adrenal medulla",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20446,
        20630
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025321",
          "MEDGEN:151941",
          "NCIT:C4895",
          "SCTID:91968002",
          "UMLS:C0686512",
          "icd11.foundation:1573786673"
        ],
        "synonyms": [
          "adrenal medulla benign neoplasm",
          "benign adrenal medulla neoplasm",
          "benign adrenal medulla tumor",
          "benign adrenal medulla tumour",
          "benign neoplasm of the adrenal medulla",
          "benign tumor of adrenal medulla",
          "benign tumor of the adrenal medulla",
          "benign tumour of adrenal medulla",
          "benign tumour of the adrenal medulla"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the adrenal medulla."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021468"
    }
  ],
  "roots": [
    {
      "id": 20437,
      "label": "adrenal gland neoplasm"
    }
  ]
}