{
  "id": 20460,
  "label": "gallbladder neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021253",
  "properties": {
    "xrefs": [
      "EFO:0004606",
      "MEDGEN:42134",
      "MESH:D005706",
      "NCIT:C3048",
      "UMLS:C0016978"
    ],
    "synonyms": [
      "gall bladder neoplasm",
      "gall bladder neoplasm (disease)",
      "gall bladder tumor",
      "gall bladder tumour",
      "gallbladder tumor",
      "gallbladder tumour",
      "neoplasm of gall bladder",
      "neoplasm of gallbladder",
      "neoplasm of the gallbladder",
      "tumor of gall bladder",
      "tumor of gallbladder",
      "tumor of the gallbladder",
      "tumour of gall bladder",
      "tumour of gallbladder",
      "tumour of the gallbladder"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A neoplasm (disease) that involves the gall bladder."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 4585,
      "label": "hepatobiliary neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4586,
        20434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080355",
          "EFO:0008550",
          "MEDGEN:208891",
          "NCIT:C8614",
          "UMLS:C0854196"
        ],
        "synonyms": [
          "hepatic and biliary neoplasms",
          "hepatic and biliary tumors",
          "hepatic and biliary tumours",
          "hepatic, biliary, and gallbladder neoplasms",
          "hepato-biliary neoplasm",
          "hepato-biliary tumor",
          "hepato-biliary tumour",
          "hepatobiliary neoplasm",
          "hepatobiliary system neoplasm",
          "hepatobiliary system neoplasm (disease)",
          "hepatobiliary system tumor",
          "hepatobiliary system tumour",
          "hepatobiliary tumor",
          "hepatobiliary tumors",
          "hepatobiliary tumour",
          "hepatobiliary tumours",
          "liver and biliary neoplasm",
          "liver and biliary system neoplasm",
          "neoplasm of hepatobiliary system",
          "tumor of hepatobiliary system",
          "tumour of hepatobiliary system",
          "hepatobiliary benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the liver parenchyma, bile ducts, and gallbladder. Representative examples of benign neoplasms include hepatocellular adenoma, bile duct adenoma, and gallbladder lipoma. Representative examples of malignant neoplasms include hepatocellular carcinoma, intrahepatic and extrahepatic cholangiocarcinoma, and gallbladder carcinoma."
      },
      "child_count": 4,
      "reference_id": "MONDO:0002514"
    },
    {
      "id": 6977,
      "label": "gallbladder disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4586
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060262",
          "EFO:0003832",
          "ICD10CM:K82",
          "ICD9:575.8",
          "ICD9:575.9",
          "MEDGEN:8947",
          "MESH:D005705",
          "NCIT:C34631",
          "SCTID:39621005",
          "UMLS:C0016977"
        ],
        "synonyms": [
          "Gall bladder disorder",
          "disease of gall bladder",
          "disease or disorder of gall bladder",
          "disorder of gall bladder",
          "gall bladder disease",
          "gall bladder disease or disorder",
          "gallbladder disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A disease involving the gall bladder."
      },
      "child_count": 11,
      "reference_id": "MONDO:0005281"
    }
  ],
  "children": [
    {
      "id": 4589,
      "label": "gallbladder papillary neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20336,
        20460
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3120",
          "MEDGEN:234293",
          "NCIT:C7130",
          "UMLS:C1333754"
        ],
        "synonyms": [
          "gall bladder papillary epithelial neoplasm",
          "gallbladder papillary neoplasm",
          "gallbladder papillomatosis",
          "intracystic papillary neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A non-invasive, papillary epithelial neoplasm that arises from the epithelium of the gallbladder. Intraepithelial neoplasia is present."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002518"
    },
    {
      "id": 7085,
      "label": "gallbladder cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4587,
        20460
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3121",
          "GARD:0009328",
          "ICD10CM:C23",
          "ICD9:156.0",
          "ICD9:156.8",
          "MEDGEN:57784",
          "NCIT:C7481",
          "ONCOTREE:GBC",
          "SCTID:363353009",
          "UMLS:C0153452",
          "icd11.foundation:922082116"
        ],
        "synonyms": [
          "gallbladder neoplasm",
          "tumor of the gallbladder",
          "tumour of the gallbladder",
          "cancer of gall bladder",
          "gall bladder cancer",
          "malignant gall bladder neoplasm",
          "malignant gallbladder neoplasm",
          "malignant gallbladder tumor",
          "malignant gallbladder tumour",
          "malignant neoplasm of gall bladder",
          "malignant neoplasm of gallbladder",
          "malignant neoplasm of the gallbladder",
          "malignant tumor of gallbladder",
          "malignant tumor of the gallbladder",
          "malignant tumour of gallbladder",
          "malignant tumour of the gallbladder",
          "localised malignant gallbladder neoplasm",
          "localized malignant gallbladder neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the gall bladder"
      },
      "child_count": 10,
      "reference_id": "MONDO:0005411"
    },
    {
      "id": 7769,
      "label": "gallbladder adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7737,
        20460,
        20555
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050893",
          "EFO:1000263",
          "MEDGEN:116046",
          "NCIT:C7720",
          "UMLS:C0238137",
          "icd11.foundation:1229475359"
        ],
        "synonyms": [
          "adenoma of gallbladder",
          "adenoma of the gallbladder",
          "gall bladder adenoma",
          "gallbladder adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A polypoid epithelial neoplasm that arises from the gallbladder. According to the neoplastic growth pattern, it is classified as tubular, tubulopapillary, or papillary."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006216"
    },
    {
      "id": 7771,
      "label": "gallbladder biliary intraepithelial neoplasia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20460
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000265",
          "MEDGEN:317714",
          "NCIT:C43606",
          "UMLS:C1708174"
        ],
        "synonyms": [
          "gallbladder BilIN",
          "gallbladder biliary intraepithelial neoplasia",
          "gallbladder dysplasia",
          "gallbladder intraepithelial neoplasia",
          "intracystic BilIN",
          "intracystic biliary intraepithelial neoplasia"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A neoplastic, non-invasive lesion that affects the gallbladder epithelium. It is characterized by the presence of atypical epithelial cells with an increased nuclear/cytoplasmic ratio, nuclear hyperchromasia, and loss of nuclear polarity."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006218"
    },
    {
      "id": 20623,
      "label": "benign neoplasm of gallbladder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2884,
        20460
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080640",
          "MEDGEN:87524",
          "NCIT:C4440",
          "SCTID:92117002",
          "UMLS:C0345912",
          "icd11.foundation:1439916526"
        ],
        "synonyms": [
          "benign gallbladder neoplasm",
          "benign gallbladder tumor",
          "benign gallbladder tumour",
          "benign neoplasm of the gallbladder",
          "benign tumor of gallbladder",
          "benign tumor of the gallbladder",
          "benign tumour of gallbladder",
          "benign tumour of the gallbladder",
          "gall bladder benign neoplasm",
          "gallbladder benign neoplasm",
          "gallbladder benign tumor",
          "gallbladder benign tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the gall bladder."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021503"
    },
    {
      "id": 21455,
      "label": "gallbladder neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20460,
        21456
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025405",
          "MEDGEN:474748",
          "NCIT:C96917",
          "UMLS:C3273115"
        ],
        "synonyms": [
          "gall bladder NET",
          "gall bladder neuroendocrine neoplasm",
          "gall bladder neuroendocrine tumor",
          "gall bladder neuroendocrine tumor, well differentiated, low or intermediate grade",
          "gall bladder neuroendocrine tumour",
          "gallbladder neuroendocrine neoplasm",
          "neuroendocrine neoplasm of gall bladder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation that arises from the gallbladder. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
      },
      "child_count": 4,
      "reference_id": "MONDO:0024502"
    }
  ],
  "roots": [
    {
      "id": 4585,
      "label": "hepatobiliary neoplasm"
    },
    {
      "id": 6977,
      "label": "gallbladder disorder"
    }
  ]
}