{
  "id": 20501,
  "label": "malignant tumor of meninges",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021322",
  "properties": {
    "xrefs": [
      "GARD:0025313",
      "ICD10CM:C70",
      "MEDGEN:87594",
      "NCIT:C4628",
      "SCTID:363497007",
      "UMLS:C0348375"
    ],
    "synonyms": [
      "cancer of meningeal cluster",
      "cancer of meninges",
      "cancer of the meninges",
      "malignant meningeal cluster neoplasm",
      "malignant meningeal neoplasms",
      "malignant meningeal tumor",
      "malignant meningeal tumour",
      "malignant meninges neoplasm",
      "malignant meninges tumor",
      "malignant meninges tumour",
      "malignant neoplasm of meningeal cluster",
      "malignant neoplasm of meninges",
      "malignant neoplasm of the meninges",
      "malignant neoplasms of meninges",
      "malignant tumor of the meninges",
      "malignant tumour of the meninges",
      "meningeal cancer",
      "meningeal cluster cancer",
      "meningeal tumors, malignant"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A cancer that involves the meningeal cluster."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 10,
  "parents": [
    {
      "id": 4753,
      "label": "central nervous system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7479,
        7694
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3620",
          "EFO:0000326",
          "GARD:0027614",
          "ICD9:239.7",
          "MEDGEN:87593",
          "MESH:D016543",
          "NANDO:2100007",
          "NCIT:C4627",
          "SCTID:126951006",
          "UMLS:C0348374"
        ],
        "synonyms": [
          "CNS neoplasm",
          "central nervous system tumor",
          "central nervous system tumour",
          "CNS cancer",
          "CNS malignant neoplasms",
          "CNS neoplasms, malignant",
          "cancer of CNS",
          "cancer of central nervous system",
          "cancer of the CNS",
          "cancer of the central nervous system",
          "central nervous system cancer",
          "central nervous system neoplasms, malignant",
          "central nervous system tumours",
          "malignant CNS neoplasm",
          "malignant CNS neoplasms",
          "malignant CNS tumor",
          "malignant CNS tumour",
          "malignant central nervous system neoplasm",
          "malignant central nervous system tumor",
          "malignant central nervous system tumour",
          "malignant neoplasm of CNS",
          "malignant neoplasm of central nervous system",
          "malignant neoplasm of the CNS",
          "malignant neoplasm of the central nervous system",
          "malignant tumor of CNS",
          "malignant tumor of central nervous system",
          "malignant tumor of the CNS",
          "malignant tumor of the central nervous system",
          "malignant tumour of CNS",
          "malignant tumour of central nervous system",
          "malignant tumour of the CNS",
          "malignant tumour of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the central nervous system"
      },
      "child_count": 40,
      "reference_id": "MONDO:0002714"
    },
    {
      "id": 17192,
      "label": "tumor of meninges",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7694
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003851",
          "GARD:0020737",
          "ICD9:239.7",
          "MEDGEN:44353",
          "MedDRA:10061282",
          "NCIT:C3229",
          "ONCOTREE:MNGT",
          "Orphanet:252025",
          "SCTID:126965008",
          "UMLS:C0025284"
        ],
        "synonyms": [
          "meningeal cluster neoplasm",
          "meningeal cluster neoplasm (disease)",
          "meningeal cluster rare nervous system tumor",
          "meningeal cluster rare nervous system tumour",
          "meningeal cluster tumor",
          "meningeal cluster tumour",
          "meningeal neoplasm",
          "meningeal neoplasms",
          "meningeal tumor",
          "meningeal tumour",
          "meninges neoplasm",
          "meninges tumor",
          "meninges tumour",
          "neoplasm of meningeal cluster",
          "neoplasm of meninges",
          "neoplasm of the meninges",
          "tumor of meningeal cluster",
          "tumor of meninges",
          "tumor of the meninges",
          "tumour of meningeal cluster",
          "tumour of the meninges",
          "meningothelial tumor",
          "meningothelial tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the meninges. The majority of the neoplasms arise from meningothelial cells and are called meningiomas. Non-meningothelial cell neoplasms include mesenchymal, non-meningothelial tumors, hemangiopericytomas, and melanocytic lesions."
      },
      "child_count": 5,
      "reference_id": "MONDO:0016743"
    }
  ],
  "children": [
    {
      "id": 4805,
      "label": "intraventricular meningioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4729,
        17113,
        20501
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3772",
          "GARD:0023242",
          "MEDGEN:232669",
          "NCIT:C5273",
          "UMLS:C1334271"
        ],
        "synonyms": [
          "brain ventricle meningioma (disease)",
          "meningioma (disease) of brain ventricle"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the ventricles of the brain."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002772"
    },
    {
      "id": 5176,
      "label": "meninges hemangiopericytoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6821,
        20501
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4957",
          "GARD:0023413",
          "MEDGEN:83894",
          "NCIT:C4660",
          "ONCOTREE:HPCCNS",
          "SCTID:277522009",
          "UMLS:C0349622"
        ],
        "synonyms": [
          "hemangiopericytoma of meninges",
          "hemangiopericytoma of the meninges",
          "meningeal cluster hemangiopericytoma",
          "meningeal cluster spindle cell tumor",
          "meningeal cluster spindle cell tumour",
          "meningeal hemangiopericytoma",
          "meningeal solitary fibrous tumor/hemangiopericytoma",
          "meninges hemangiopericytoma",
          "hemangiopericytoma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A solitary fibrous tumor/hemangiopericytoma that arises from the meninges."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003223"
    },
    {
      "id": 5527,
      "label": "lung meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        10167,
        17113,
        20501
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5764",
          "GARD:0023596",
          "MEDGEN:232712",
          "NCIT:C5668",
          "UMLS:C1334450"
        ],
        "synonyms": [
          "lung meningioma",
          "lung meningioma (disease)",
          "meningioma (disease) of lung",
          "meningioma of lung",
          "meningioma of the lung",
          "pulmonary meningioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A primary or metastatic meningioma that is present in the lung. The lung is the most frequent site of metastasis of meningiomas."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003638"
    },
    {
      "id": 5642,
      "label": "malignant leptomeningeal tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17113,
        20501
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6086",
          "GARD:0023657",
          "MEDGEN:233153",
          "NCIT:C8506",
          "UMLS:C1334596"
        ],
        "synonyms": [
          "cancer of leptomeninx",
          "leptomeninx cancer",
          "malignant leptomeningeal neoplasm",
          "malignant leptomeningeal tumor",
          "malignant leptomeninx neoplasm",
          "malignant neoplasm of leptomeninx",
          "malignant tumor of leptomeninges",
          "leptomeningeal cancer",
          "malignant neoplasm of leptomeninges",
          "malignant neoplasm of the leptomeninges",
          "malignant tumor of the leptomeninges",
          "malignant tumour of the leptomeninges"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant tumor involving the leptomeninges."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003762"
    },
    {
      "id": 5652,
      "label": "cerebral meningioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4768,
        20501,
        25197
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6112",
          "GARD:0023663",
          "MEDGEN:154239",
          "NCIT:C4807",
          "SCTID:189164002",
          "UMLS:C0542564"
        ],
        "synonyms": [
          "cerebral hemispheric meningioma",
          "meningioma (disease) of telencephalon",
          "meningioma of cerebral hemispheres",
          "meningioma of cerebrum",
          "meningioma of the cerebral hemispheres",
          "meningioma of the cerebrum",
          "telencephalon meningioma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the cerebral hemispheres."
      },
      "child_count": 12,
      "reference_id": "MONDO:0003772"
    },
    {
      "id": 5978,
      "label": "spinal meninges cancer",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5449,
        20501
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7224",
          "GARD:0023851",
          "ICD10CM:C70.1",
          "ICD9:192.3",
          "MEDGEN:509351",
          "NCIT:C194412",
          "SCTID:363476006",
          "UMLS:C0153647",
          "icd11.foundation:1701274048"
        ],
        "synonyms": [
          "cancer of meninx of spinal cord",
          "malignant meninx of spinal cord neoplasm",
          "malignant neoplasm of meninx of spinal cord",
          "malignant neoplasm of spinal meninges",
          "meninx of spinal cord cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the meninx of spinal cord."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004151"
    },
    {
      "id": 6124,
      "label": "meningeal sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4336,
        20501
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7614",
          "GARD:0023924",
          "MEDGEN:90148",
          "NCIT:C4073",
          "UMLS:C0302327"
        ],
        "synonyms": [
          "meningeal cluster sarcoma",
          "meningeal sarcoma",
          "meninges sarcoma",
          "sarcoma of meningeal cluster",
          "sarcoma of meninges",
          "sarcoma of the meninges"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare sarcoma arising from the meninges."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004308"
    },
    {
      "id": 6237,
      "label": "skin meningioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4907,
        17113,
        20501
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8006",
          "GARD:0023999",
          "MEDGEN:698541",
          "UMLS:C1275260"
        ],
        "synonyms": [
          "meningioma (disease) of zone of skin",
          "zone of skin meningioma (disease)",
          "primary meningioma of the skin"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma (disease) that involves the zone of skin."
      },
      "child_count": 3,
      "reference_id": "MONDO:0004429"
    },
    {
      "id": 6314,
      "label": "meningeal melanomatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5968,
        17195,
        20501
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8243",
          "GARD:0024044",
          "ICDO:8728/3",
          "MEDGEN:226843",
          "NCIT:C6891",
          "UMLS:C1266114"
        ],
        "synonyms": [
          "melanomatosis of meningeal cluster",
          "meningeal cluster melanomatosis",
          "meningeal melanomatosis",
          "meningeal melanomatosis (morphologic abnormality)",
          "leptomeningeal melanomatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningeal melanoma with secondary diffuse meningeal spread. (WHO)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0004512"
    },
    {
      "id": 20050,
      "label": "anaplastic meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20048,
        20049,
        20078,
        20501
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025191",
          "ICDO:9530/3",
          "MEDGEN:75478",
          "NCIT:C4051",
          "ONCOTREE:ANM",
          "UMLS:C0259785"
        ],
        "synonyms": [
          "anaplastic (malignant) meningioma",
          "anaplastic meningioma",
          "malignant meningioma",
          "meningioma, anaplastic, malignant",
          "meningioma, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A WHO grade III meningioma characterized by the presence of malignant morphologic features, including malignant cytology and a very high mitotic index (20 or more mitoses per ten high power fields)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020635"
    }
  ],
  "roots": [
    {
      "id": 4753,
      "label": "central nervous system cancer"
    },
    {
      "id": 17192,
      "label": "tumor of meninges"
    }
  ]
}