{
  "id": 20517,
  "label": "neoplasm of testis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021348",
  "properties": {
    "xrefs": [
      "ICD9:239.5",
      "MEDGEN:52675",
      "NCIT:C3404",
      "ONCOTREE:TESTIS",
      "SCTID:126900000",
      "UMLS:C0039590"
    ],
    "synonyms": [
      "neoplasm of testis",
      "neoplasm of the testis",
      "testicular neoplasm",
      "testicular tumor",
      "testicular tumour",
      "testis neoplasm",
      "testis neoplasm (disease)",
      "testis tumor",
      "testis tumour",
      "tumor of testis",
      "tumor of the testis",
      "tumour of testis",
      "tumour of the testis"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A neoplasm (disease) that involves the testis."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 4435,
      "label": "testicular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4375,
        5121
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2519",
          "EFO:0009601",
          "ICD9:608.89",
          "MEDGEN:11743",
          "MESH:D013733",
          "NCIT:C26890",
          "SCTID:64910008",
          "UMLS:C0039584"
        ],
        "synonyms": [
          "disease of testis",
          "disease or disorder of testis",
          "disorder of testis",
          "testicular disease",
          "testicular disorder",
          "testis disease",
          "testis disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia."
      },
      "child_count": 16,
      "reference_id": "MONDO:0002329"
    },
    {
      "id": 21521,
      "label": "male reproductive system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5121,
        7638
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:239.5",
          "MEDGEN:42196",
          "NCIT:C3054",
          "SCTID:126895004",
          "UMLS:C0017417"
        ],
        "synonyms": [
          "Male reproductive system neoplasm",
          "Male reproductive system tumor",
          "Male reproductive system tumour",
          "male reproductive organ neoplasm",
          "male reproductive organ tumor",
          "male reproductive organ tumour",
          "neoplasm of Male reproductive system",
          "neoplasm of male reproductive organ",
          "neoplasm of the Male reproductive system",
          "tumor of Male reproductive system",
          "tumor of male reproductive organ",
          "tumor of the Male reproductive system",
          "tumour of Male reproductive system",
          "tumour of male reproductive organ",
          "tumour of the Male reproductive system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign, borderline, or malignant neoplasm that affects the male reproductive system. Representative examples include benign prostate phyllodes tumor, benign testicular Sertoli cell tumor, prostatic intraepithelial neoplasia, prostate carcinoma, testicular seminoma, and testicular embryonal carcinoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0024582"
    }
  ],
  "children": [
    {
      "id": 4818,
      "label": "seminal vesicle tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3855",
          "ICD9:239.5",
          "MEDGEN:90967",
          "NCIT:C39908",
          "SCTID:236740006",
          "UMLS:C0341767"
        ],
        "synonyms": [
          "neoplasm of seminal vesicle",
          "seminal vesicle neoplasm",
          "seminal vesicle neoplasm (disease)",
          "seminal vesicle tumor",
          "tumor of seminal vesicle"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the seminal vesicle. Representative examples include cystadenoma and adenocarcinoma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002790"
    },
    {
      "id": 5097,
      "label": "testicular Brenner tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20517,
        21291
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4739",
          "MEDGEN:273631",
          "NCIT:C39953",
          "UMLS:C1515281"
        ],
        "synonyms": [
          "testes, rudimentary Brenner tumor",
          "testes, rudimentary Brenner tumour",
          "testis Brenner tumor",
          "testis Brenner tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An uncommon usually benign neoplasm that arises from the testis. It is characterized by the presence of cysts lined by transitional cells and solid nests of transitional cells in a spindle cell stroma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003118"
    },
    {
      "id": 5102,
      "label": "testicular sex cord-stromal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7639,
        20517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4757",
          "GARD:0021551",
          "MEDGEN:825921",
          "NCIT:C6358",
          "Orphanet:363489",
          "SCTID:702406000",
          "UMLS:C3840076"
        ],
        "synonyms": [
          "sex cord-stromal tumor of testis",
          "sex cord-stromal tumour of testis",
          "testicular sex cord-stromal neoplasm",
          "testicular sex cord-stromal tumor",
          "testicular sex cord-stromal tumour",
          "testis sex cord-stromal tumor",
          "testis sex cord-stromal tumour",
          "sex cord-stromal neoplasm",
          "sex cord-stromal neoplasm of testis",
          "sex cord-stromal neoplasm of the testis",
          "sex cord-stromal tumor of the testis",
          "sex cord-stromal tumour of the testis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant tumor that arises from the testis. It is composed of granulosa cells, Leydig cells, Sertoli cells, and fibroblasts. Each of these cell types may constitute the only cellular component that is present in the tumor or it may be mixed with other cell types in various combinations. The prognosis can not always be predicted on histologic grounds alone. Approximately, ten percent of these tumors may metastasize. Representative examples include granulosa cell tumor, Leydig cell tumor, Sertoli cell tumor, and tumors of the thecoma-fibroma group."
      },
      "child_count": 20,
      "reference_id": "MONDO:0003125"
    },
    {
      "id": 5463,
      "label": "rete testis neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5639",
          "MEDGEN:308162",
          "NCIT:C39955",
          "UMLS:C1514912"
        ],
        "synonyms": [
          "neoplasm of rete testis",
          "rete testis neoplasm",
          "rete testis neoplasm (disease)",
          "rete testis tumor",
          "rete testis tumour",
          "tumor of rete testis",
          "tumour of rete testis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the rete testis. Representative examples include adenoma and adenocarcinoma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003562"
    },
    {
      "id": 7111,
      "label": "testicular cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7450,
        20517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2998",
          "EFO:0005088",
          "ICD10CM:C62",
          "ICD9:186",
          "ICD9:186.9",
          "MEDGEN:56313",
          "MESH:D013736",
          "NCIT:C7251",
          "SCTID:363449006",
          "UMLS:C0153594"
        ],
        "synonyms": [
          "testicular tumor",
          "testicular tumour",
          "testis neoplasm",
          "cancer of testis",
          "malignant neoplasm of testis",
          "malignant neoplasm of the testis",
          "malignant testicular neoplasm",
          "malignant testicular tumor",
          "malignant testicular tumour",
          "malignant testis neoplasm",
          "malignant tumor of testis",
          "malignant tumor of the testis",
          "malignant tumour of testis",
          "malignant tumour of the testis",
          "testis cancer",
          "paediatric testicular neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm that affects the testis. Representative examples include seminoma, embryonal carcinoma, sarcoma, leukemia, and lymphoma."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005447"
    },
    {
      "id": 11294,
      "label": "testicular germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18335,
        20517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5557",
          "EFO:1000566",
          "GARD:0013047",
          "ICD9:239.5",
          "MEDGEN:277809",
          "MESH:C563236",
          "NCIT:C8591",
          "OMIM:273300",
          "Orphanet:363504",
          "SCTID:713577007",
          "UMLS:C1336708"
        ],
        "synonyms": [
          "TGCT",
          "germ cell neoplasm of testis",
          "germ cell neoplasm of the testis",
          "germ cell tumor of testis",
          "germ cell tumor of the testis",
          "germ cell tumors, somatic",
          "germ cell tumour of testis",
          "germ cell tumour of the testis",
          "male germ cell tumor, somatic",
          "spermatocytic seminoma, somatic",
          "testicular germ cell neoplasm",
          "testicular germ cell neoplasms",
          "testicular germ cell tumor",
          "testicular tumor, somatic",
          "testis germ cell tumor",
          "testis germ cell tumour",
          "Male germ cell tumor",
          "Male germ cell tumour",
          "embryonal cell carcinoma",
          "endodermal sinus tumor",
          "endodermal sinus tumour",
          "nonseminomatous germ cell tumors",
          "nonseminomatous germ cell tumours",
          "seminoma",
          "spermatocytic seminoma",
          "teratoma, testicular",
          "testicular germ cell cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A germ cell tumor arising from the testis. Representative examples include teratoma, seminoma, embryonal carcinoma, and yolk sac tumor."
      },
      "child_count": 12,
      "reference_id": "MONDO:0010108"
    },
    {
      "id": 20570,
      "label": "benign neoplasm of testis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3030,
        20517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:D29.2",
          "ICD9:222.0",
          "MEDGEN:57576",
          "NCIT:C3612",
          "SCTID:92428008",
          "UMLS:C0154007",
          "icd11.foundation:815021426"
        ],
        "synonyms": [
          "benign neoplasm of the testis",
          "benign testicular neoplasm",
          "benign testicular tumor",
          "benign testicular tumour",
          "benign tumor of testis",
          "benign tumor of the testis",
          "benign tumour of testis",
          "benign tumour of the testis",
          "testis benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the testis."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021447"
    },
    {
      "id": 22958,
      "label": "childhood testicular neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20320,
        20517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:272472",
          "NCIT:C5053",
          "UMLS:C1333010"
        ],
        "synonyms": [
          "childhood neoplasm of testis",
          "childhood neoplasm of the testis",
          "childhood testicular neoplasm",
          "neoplasm of testis of childhood",
          "paediatric neoplasm of testis",
          "paediatric neoplasm of the testis",
          "paediatric testicular neoplasm",
          "pediatric neoplasm of testis",
          "pediatric neoplasm of the testis",
          "pediatric testicular neoplasm",
          "testicular tumor, childhood"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm that arises from the testis during childhood."
      },
      "child_count": 2,
      "reference_id": "MONDO:0037250"
    }
  ],
  "roots": [
    {
      "id": 4435,
      "label": "testicular disorder"
    },
    {
      "id": 21521,
      "label": "male reproductive system neoplasm"
    }
  ]
}