{ "id": 20522, "label": "neoplasm of esophagus", "model": { "label": "Mondo Disease Ontology (MONDO)", "source": 0 }, "type_id": 0, "reference_id": "MONDO:0021355", "properties": { "xrefs": [ "MEDGEN:4547", "NCIT:C3028", "SCTID:126817006", "UMLS:C0014859" ], "synonyms": [ "esophageal neoplasm", "esophageal neoplasms, benign and malignant", "esophageal tumor", "esophageal tumors", "esophageal tumour", "esophageal tumours", "esophagus neoplasm", "esophagus neoplasm (disease)", "esophagus tumor", "neoplasm of esophagus", "neoplasm of the esophagus", "neoplasm of the oesophagus", "oesophagus neoplasm", "oesophagus neoplasm (disease)", "oesophagus tumour", "tumor of esophagus", "tumor of the esophagus", "tumour of oesophagus", "tumour of the oesophagus" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A neoplasm (disease) that involves the esophagus." }, "isLeaf": false, "isRoot": false, "child_count": 5, "parents": [ { "id": 5629, "label": "esophageal disorder", "isLeaf": false, "isRoot": false, "parents": [ 23495 ], "type_id": 0, "properties": { "xrefs": [ "DOID:6050", "EFO:0009544", "ICD9:530", "ICD9:530.2", "ICD9:530.20", "ICD9:530.9", "MEDGEN:8693", "MESH:D004935", "NCIT:C3027", "SCTID:30811009", "SCTID:37657006", "UMLS:C0014852", "icd11.foundation:1594312948" ], "synonyms": [ "disease of esophagus", "disease of oesophagus", "disease or disorder of esophagus", "disease or disorder of oesophagus", "disorder of esophagus", "disorder of oesophagus", "esophageal disorder", "esophagus disease", "esophagus disease or disorder", "oesophagus disease", "oesophagus disease or disorder", "esophageal ulcer" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas." }, "child_count": 20, "reference_id": "MONDO:0003749" }, { "id": 20434, "label": "digestive system neoplasm", "isLeaf": false, "isRoot": false, "parents": [ 6798 ], "type_id": 0, "properties": { "xrefs": [ "EFO:0008549", "MEDGEN:8398", "MESH:D005770", "NCIT:C3052", "UMLS:C0012243" ], "synonyms": [ "GI neoplasm", "GI system neoplasm", "GI system tumor", "GI system tumour", "GI tumor", "GI tumour", "digestive neoplasm", "digestive system neoplasm (disease)", "digestive system tumor", "digestive system tumour", "digestive tumor", "digestive tumour", "gastrointestinal neoplasm", "gastrointestinal system neoplasm", "gastrointestinal system tumor", "gastrointestinal system tumour", "gastrointestinal tumor", "gastrointestinal tumour", "neoplasm of GI system", "neoplasm of digestive system", "neoplasm of gastrointestinal system", "neoplasm of the GI system", "neoplasm of the digestive system", "neoplasm of the gastrointestinal system", "tumor of GI system", "tumor of digestive system", "tumor of gastrointestinal system", "tumor of the GI system", "tumor of the digestive system", "tumor of the gastrointestinal system", "tumour of GI system", "tumour of digestive system", "tumour of gastrointestinal system", "tumour of the GI system", "tumour of the digestive system", "tumour of the gastrointestinal system" ], "definition": "A neoplasm (disease) that involves the digestive system." }, "child_count": 23, "reference_id": "MONDO:0021223" } ], "children": [ { "id": 5196, "label": "esophageal granular cell tumor", "isLeaf": true, "isRoot": false, "parents": [ 7788, 20522 ], "type_id": 0, "properties": { "xrefs": [ "DOID:5040", "GARD:0023422", "MEDGEN:234228", "NCIT:C5700", "UMLS:C1333448", "icd11.foundation:1070074406" ], "synonyms": [ "esophageal granular cell myoblastoma", "esophageal granular cell neoplasm", "esophageal granular cell tumor", "esophagus granular cell tumor", "granular cell esophageal tumor", "granular cell esophageal tumour", "granular cell esophagus myoblastoma", "granular cell esophagus neoplasm", "granular cell esophagus tumor", "granular cell myoblastoma of esophagus", "granular cell myoblastoma of oesophagus", "granular cell myoblastoma of the esophagus", "granular cell myoblastoma of the oesophagus", "granular cell neoplasm of esophagus", "granular cell neoplasm of oesophagus", "granular cell neoplasm of the esophagus", "granular cell neoplasm of the oesophagus", "granular cell oesophagus myoblastoma", "granular cell oesophagus neoplasm", "granular cell oesophagus tumour", "granular cell tumor of esophagus", "granular cell tumor of the esophagus", "granular cell tumour of oesophagus", "granular cell tumour of the oesophagus", "oesophagus granular cell tumour", "malignant granular cell esophageal tumor", "malignant granular cell esophageal tumour" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" }, { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A tumor that usually presents with small nodules or small sessile polyps, predominantly in the distal esophagus. Histologically, it is composed of sheets of oval to polygonal cells with a small central nucleus and abundant granular cytoplasm. This is usually a benign tumor. (WHO, 2000) -- 2003" }, "child_count": 0, "reference_id": "MONDO:0003251" }, { "id": 5537, "label": "esophageal neuroendocrine tumor", "isLeaf": false, "isRoot": false, "parents": [ 2885, 20522 ], "type_id": 0, "properties": { "xrefs": [ "DOID:5784", "GARD:0022058", "MEDGEN:459486", "NCIT:C95616", "Orphanet:506136", "UMLS:C2987260", "icd11.foundation:1167478749", "icd11.foundation:890879256" ], "synonyms": [ "NEN of esophagus", "NEN of oesophagus", "esophageal NEN", "esophageal NET", "esophageal neuroendocrine neoplasm", "esophageal neuroendocrine tumor", "esophageal well differentiated endocrine tumor", "esophageal well differentiated endocrine tumor/carcinoma", "esophageal well differentiated endocrine tumour", "esophagus NET", "esophagus neuroendocrine neoplasm", "esophagus neuroendocrine tumor", "esophagus neuroendocrine tumor, well differentiated, low or intermediate grade", "neuroendocrine neoplasm of esophagus", "neuroendocrine neoplasm of oesophagus", "neuroendocrine tumour of oesophagus", "oesophagus NET", "oesophagus neuroendocrine neoplasm", "oesophagus neuroendocrine tumor, well differentiated, low or intermediate grade", "oesophagus neuroendocrine tumour" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" }, { "ref": "MONDO:0005151", "name": "endocrine system disorder" } ], "definition": "A well differentiated, low or intermediate grade tumor with neuroendocrine differentiation that arises from the esophagus." }, "child_count": 2, "reference_id": "MONDO:0003649" }, { "id": 6595, "label": "neurofibroma of the esophagus", "isLeaf": true, "isRoot": false, "parents": [ 17201, 20522 ], "type_id": 0, "properties": { "xrefs": [ "DOID:961", "GARD:0024117", "MEDGEN:232164", "NCIT:C5704", "UMLS:C1333463" ], "synonyms": [ "esophageal neurofibroma", "esophagus neurofibroma", "neurofibroma of esophagus", "neurofibroma of oesophagus", "neurofibroma of the esophagus", "oesophagus neurofibroma" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" }, { "ref": "MONDO:0005071", "name": "nervous system disorder" } ], "definition": "A non-metastasizing encapsulated neoplasm arising from nerves in the esophagus. Morphologically, it is characterized by the presence of fibroblasts and Schwann cells." }, "child_count": 0, "reference_id": "MONDO:0004837" }, { "id": 8953, "label": "esophageal cancer", "isLeaf": false, "isRoot": false, "parents": [ 4587, 20522 ], "type_id": 0, "properties": { "xrefs": [ "DOID:5041", "GARD:0027778", "ICD10CM:C15", "ICD9:150.3", "ICD9:150.4", "ICD9:150.5", "ICD9:150.8", "ICD9:150.9", "MEDGEN:107792", "NCIT:C7478", "OMIM:133239", "SCTID:363402007", "UMLS:C0546837", "icd11.foundation:669033105" ], "synonyms": [ "cancer of esophagus", "cancer of oesophagus", "esophageal cancer", "esophageal cancer, somatic", "esophageal carcinoma, somatic", "esophageal squamous cell carcinoma, somatic", "esophagus cancer", "malignant esophageal neoplasm", "malignant esophageal tumor", "malignant esophageal tumour", "malignant esophagus neoplasm", "malignant esophagus tumor", "malignant neoplasm of esophagus", "malignant neoplasm of oesophagus", "malignant neoplasm of the esophagus", "malignant neoplasm of the oesophagus", "malignant oesophagus neoplasm", "malignant oesophagus tumour", "malignant tumor of esophagus", "malignant tumor of the esophagus", "malignant tumour of oesophagus", "malignant tumour of the oesophagus", "oesophagus cancer", "Ca lower third esophagus", "Ca lower third oesophagus", "Ca middle third esophagus", "Ca middle third oesophagus", "malignant neoplasm of distal third of esophagus", "malignant neoplasm of distal third of oesophagus", "malignant neoplasm of lower third of esophagus", "malignant neoplasm of lower third of oesophagus", "malignant neoplasm of middle third of esophagus", "malignant neoplasm of middle third of oesophagus", "malignant neoplasm of proximal third of esophagus", "malignant neoplasm of proximal third of oesophagus", "malignant neoplasm of upper third esophagus", "malignant neoplasm of upper third oesophagus", "malignant tumor of abdominal esophagus", "malignant tumor of distal third of esophagus", "malignant tumor of proximal third of esophagus", "malignant tumor of the middle third of the esophagus", "malignant tumour of abdominal oesophagus", "malignant tumour of distal third of oesophagus", "malignant tumour of proximal third of oesophagus", "malignant tumour of the middle third of the oesophagus", "Aerodigestive tract cancer, susceptibility to", "Escc, susceptibility to", "esophageal squamous cell carcinoma, susceptibility to", "gastric cardia adenocarcinoma, susceptibility to" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A primary or metastatic malignant neoplasm involving the esophagus." }, "child_count": 14, "reference_id": "MONDO:0007576" }, { "id": 20581, "label": "benign neoplasm of esophagus", "isLeaf": false, "isRoot": false, "parents": [ 2884, 20522 ], "type_id": 0, "properties": { "xrefs": [ "ICD10CM:D13.0", "ICD9:211.0", "MEDGEN:102297", "NCIT:C3598", "SCTID:92091003", "UMLS:C0153942", "icd11.foundation:1827459816" ], "synonyms": [ "benign esophageal neoplasm", "benign esophageal tumor", "benign esophageal tumour", "benign esophagus neoplasm", "benign esophagus tumor", "benign neoplasm of the esophagus", "benign neoplasm of the oesophagus", "benign oesophagus neoplasm", "benign oesophagus tumour", "benign tumor of esophagus", "benign tumor of the esophagus", "benign tumour of oesophagus", "benign tumour of the oesophagus", "esophagus benign neoplasm", "oesophagus benign neoplasm" ], "categories": [ { "ref": "MONDO:0004335", "name": "digestive system disorder" } ], "definition": "A benign neoplasm that involves the esophagus." }, "child_count": 6, "reference_id": "MONDO:0021459" } ], "roots": [ { "id": 5629, "label": "esophageal disorder" }, { "id": 20434, "label": "digestive system neoplasm" } ] }