{
  "id": 20541,
  "label": "extrahepatic bile duct neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021385",
  "properties": {
    "xrefs": [
      "MEDGEN:91056",
      "NCIT:C4441",
      "SCTID:126855001",
      "UMLS:C0345913"
    ],
    "synonyms": [
      "extrahepatic bile duct neoplasm",
      "extrahepatic bile duct neoplasm (disease)",
      "extrahepatic bile duct tumor",
      "extrahepatic bile duct tumour",
      "neoplasm of extrahepatic bile duct",
      "neoplasm of the extrahepatic bile duct",
      "tumor of extrahepatic bile duct",
      "tumor of the extrahepatic bile duct",
      "tumour of extrahepatic bile duct",
      "tumour of the extrahepatic bile duct"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A benign or malignant neoplasm that affects the extrahepatic bile ducts. Representative examples include adenoma and adenocarcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 20714,
      "label": "bile duct neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4900,
        6998
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:14114",
          "MESH:D001650",
          "NCIT:C2898",
          "UMLS:C0005396"
        ],
        "synonyms": [
          "bile duct neoplasm",
          "bile duct neoplasm (disease)",
          "bile duct tumor",
          "bile duct tumour",
          "intrahepatic and extrahepatic bile duct neoplasm",
          "intrahepatic and extrahepatic bile duct tumor",
          "intrahepatic and extrahepatic bile duct tumour",
          "neoplasm of bile duct",
          "tumor of bile duct",
          "tumour of bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the intrahepatic or extrahepatic bile ducts. Representative examples of benign neoplasms include bile duct adenoma and extrahepatic bile duct lipoma. Representative examples of malignant neoplasms include intrahepatic and extrahepatic cholangiocarcinoma."
      },
      "child_count": 8,
      "reference_id": "MONDO:0021662"
    }
  ],
  "children": [
    {
      "id": 3247,
      "label": "extrahepatic bile duct lipoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3234,
        20541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10209",
          "MEDGEN:232482",
          "NCIT:C5854",
          "UMLS:C1333509"
        ],
        "synonyms": [
          "extrahepatic bile duct lipoma",
          "lipoma of extrahepatic bile duct",
          "lipoma of the extrahepatic bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare benign adipose tissue neoplasm of the extrahepatic bile duct."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000978"
    },
    {
      "id": 5227,
      "label": "extrahepatic bile duct leiomyoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6499,
        20541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5125",
          "MEDGEN:232169",
          "NCIT:C5855",
          "UMLS:C1333507"
        ],
        "synonyms": [
          "extrahepatic bile duct leiomyoma",
          "leiomyoma of extrahepatic bile duct",
          "leiomyoma of the extrahepatic bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign smooth muscle neoplasm arising from an extrahepatic bile duct. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003286"
    },
    {
      "id": 5371,
      "label": "extrahepatic bile duct adenoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7679,
        20541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5438",
          "MEDGEN:233098",
          "NCIT:C5857",
          "UMLS:C1331534",
          "icd11.foundation:1322471141"
        ],
        "synonyms": [
          "adenoma of extrahepatic bile duct",
          "adenoma of the extrahepatic bile duct",
          "extrahepatic bile duct adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An adenoma that arises from the extrahepatic bile ducts. It is classified as papillary, tubular, or tubulopapillary."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003445"
    },
    {
      "id": 8170,
      "label": "common bile duct neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4899,
        20541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4608",
          "MEDGEN:3178",
          "MESH:D003138",
          "SCTID:126857009",
          "UMLS:C0009442"
        ],
        "synonyms": [
          "common bile duct neoplasm (disease)",
          "common bile duct tumor",
          "common bile duct tumour",
          "neoplasm of common bile duct",
          "tumor of common bile duct",
          "tumour of common bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Tumor or cancer of the common bile duct including the ampulla of vater and the sphincter of oddi."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006709"
    },
    {
      "id": 16047,
      "label": "gallbladder neuroendocrine tumor, grade 1/2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2885,
        20541,
        21455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019761",
          "MEDGEN:474749",
          "NCIT:C96918",
          "Orphanet:100086",
          "UMLS:C3273116"
        ],
        "synonyms": [
          "gallbladder NET",
          "gallbladder neuroendocrine tumor",
          "gallbladder neuroendocrine tumour",
          "gallbladder well differentiated endocrine tumor",
          "gallbladder well differentiated endocrine tumor/carcinoma",
          "gallbladder well differentiated endocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A well differentiated, low or intermediate grade tumor with neuroendocrine differentiation that arises from the gallbladder."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015073"
    },
    {
      "id": 18842,
      "label": "carcinoma of gallbladder and extrahepatic biliary tract",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018850",
          "MEDGEN:1797980",
          "MedDRA:10007426",
          "Orphanet:56044",
          "UMLS:C5566557"
        ],
        "synonyms": [
          "carcinoma of gallbladder and EBT"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Carcinoma of the gallbladder (GBC) is the most common and aggressive form of biliary tract cancer (BTC) usually arising in the fundus of the gallbladder, rapidly metastasizing to lymph nodes and distant sites."
      },
      "child_count": 2,
      "reference_id": "MONDO:0018918"
    },
    {
      "id": 20500,
      "label": "malignant tumor of extrahepatic bile duct",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5049,
        20541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025312",
          "ICD10CM:C24.0",
          "ICD9:156.1",
          "ICD9:156.8",
          "MEDGEN:56304",
          "NCIT:C7483",
          "SCTID:363416002",
          "UMLS:C0153453"
        ],
        "synonyms": [
          "extrahepatic bile duct cancer",
          "cancer of extrahepatic bile duct",
          "malignant extrahepatic bile duct neoplasm",
          "malignant extrahepatic bile duct tumor",
          "malignant extrahepatic bile duct tumour",
          "malignant neoplasm of extrahepatic bile duct",
          "malignant neoplasm of the extrahepatic bile duct",
          "malignant tumor of the extrahepatic bile duct",
          "malignant tumour of the extrahepatic bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A cancer that involves the extrahepatic bile duct."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021321"
    }
  ],
  "roots": [
    {
      "id": 20714,
      "label": "bile duct neoplasm"
    }
  ]
}