{
  "id": 20546,
  "label": "polyp of large intestine",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021392",
  "properties": {
    "xrefs": [
      "MEDGEN:182694",
      "NCIT:C5679",
      "SCTID:399505005",
      "UMLS:C0949059",
      "icd11.foundation:537826614"
    ],
    "synonyms": [
      "colorectal polyp",
      "large bowel polyp",
      "large intestine polyp",
      "polyp of large bowel",
      "polyp of the large bowel",
      "polyp of the large intestine"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A polyp that involves the large intestine."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 6807,
      "label": "polyp",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23519
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000662",
          "ICD10CM:N84",
          "MEDGEN:19397",
          "MESH:D011127",
          "NCIT:C3340",
          "SCTID:441456002",
          "UMLS:C0032584"
        ],
        "synonyms": [
          "polyp"
        ],
        "definition": "A usually exophytic mass attached to the underlying tissue by a broad base or a thin stalk. Polyps can be neoplastic or non-neoplastic. Neoplastic polyps usually represent proliferations of the epithelium, and are commonly seen in the gastrointestinal tract. Polyps of the gastrointestinal tract are often called adenomas, are associated with dysplasia, and may eventually transform into carcinomas. Non-neoplastic polyps may be inflammatory, degenerative, or the result of malformations."
      },
      "child_count": 21,
      "reference_id": "MONDO:0005079"
    },
    {
      "id": 21545,
      "label": "large intestine disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6756
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:574315",
          "SCTID:119523007",
          "UMLS:C0341321"
        ],
        "synonyms": [
          "disease of large intestine",
          "disease or disorder of large intestine",
          "disorder of large intestine",
          "large intestine disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A disease that involves the large intestine."
      },
      "child_count": 11,
      "reference_id": "MONDO:0024634"
    }
  ],
  "children": [
    {
      "id": 7664,
      "label": "appendix hyperplastic polyp",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7799,
        20546,
        23661
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:474394",
          "NCIT:C96416",
          "UMLS:C3272761"
        ],
        "synonyms": [
          "appendix metaplastic polyp",
          "vermiform appendix hyperplastic polyp"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A non-neoplastic polyp that arises from the appendix. It is characterized by the presence of elongated serrated crypts and the absence of atypia or dysplasia."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006090"
    },
    {
      "id": 7721,
      "label": "colorectal hamartoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7022,
        7784,
        20546
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000193",
          "MEDGEN:474434",
          "NCIT:C96474",
          "UMLS:C3272801"
        ],
        "synonyms": [
          "colorectal hamartoma",
          "colorectum hamartoma (disease)",
          "large intestinal hamartoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A non-neoplastic, hamartomatous polyp that arises from the colon and rectum. This group includes the juvenile polyp, Peutz-Jeghers polyp, and Cowden-associated polyp."
      },
      "child_count": 3,
      "reference_id": "MONDO:0006160"
    },
    {
      "id": 20549,
      "label": "polyp of rectum",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3792,
        20546
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:K62.1",
          "MEDGEN:11150",
          "NCIT:C3351",
          "SCTID:39772007",
          "UMLS:C0034887",
          "icd11.foundation:2101432719"
        ],
        "synonyms": [
          "polyp of the rectum",
          "rectal polyp",
          "rectum polyp"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A polyp that involves the rectum."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021398"
    },
    {
      "id": 20550,
      "label": "polyp of colon",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5340,
        20546
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:K63.5",
          "MEDGEN:3166",
          "MESH:D003111",
          "NCIT:C2954",
          "SCTID:68496003",
          "UMLS:C0009376",
          "icd11.foundation:1408488915"
        ],
        "synonyms": [
          "colon polyp",
          "colonic polyp",
          "polyp of the colon"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A polyp that involves the colon."
      },
      "child_count": 10,
      "reference_id": "MONDO:0021400"
    },
    {
      "id": 24024,
      "label": "POLE-related polyposis and colorectal cancer syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2742,
        18645,
        20546,
        21140
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026124"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An autosomal dominant hereditary syndrome caused by germline pathogenic POLE variants. It is characterized by the presence of colorectal polyps and colorectal cancer."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100287"
    },
    {
      "id": 24079,
      "label": "POLD1-related polyposis and colorectal cancer syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2742,
        18645,
        20546,
        21140
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026151"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An autosomal dominant hereditary syndrome caused by germline pathogenic POLD1 variants. It is characterized by the presence of colorectal polyps and colorectal cancer."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100351"
    }
  ],
  "roots": [
    {
      "id": 6807,
      "label": "polyp"
    },
    {
      "id": 21545,
      "label": "large intestine disorder"
    }
  ]
}