{
  "id": 20561,
  "label": "squamous cell carcinoma of buccal mucosa",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021431",
  "properties": {
    "xrefs": [
      "GARD:0025318",
      "MEDGEN:83627",
      "NCIT:C4040",
      "SCTID:254437001",
      "UMLS:C0280299"
    ],
    "synonyms": [
      "buccal mucosa squamous cell carcinoma",
      "scc of buccal mucosa",
      "scc of the buccal mucosa",
      "squamous cell carcinoma of the buccal mucosa"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0006858",
        "name": "mouth disorder"
      },
      {
        "ref": "MONDO:0024623",
        "name": "otorhinolaryngologic disease"
      }
    ],
    "definition": "A squamous cell carcinoma that involves the buccal mucosa."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6431,
      "label": "cheek mucosa cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7170,
        7266,
        20450
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8702",
          "ICD9:145.0",
          "MEDGEN:57550",
          "NCIT:C9320",
          "SCTID:363386008",
          "UMLS:C0153373"
        ],
        "synonyms": [
          "buccal mucosa cancer",
          "cancer of buccal mucosa",
          "malignant buccal mucosa neoplasm",
          "malignant buccal mucosa tumor",
          "malignant buccal mucosa tumour",
          "malignant neoplasm of buccal mucosa",
          "malignant neoplasm of the buccal mucosa",
          "malignant tumor of buccal mucosa",
          "malignant tumor of the buccal mucosa",
          "malignant tumour of buccal mucosa",
          "malignant tumour of the buccal mucosa"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the buccal mucosa."
      },
      "child_count": 3,
      "reference_id": "MONDO:0004645"
    },
    {
      "id": 6701,
      "label": "oral cavity squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23401,
        23483
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050866",
          "EFO:0000199",
          "GARD:0017932",
          "MEDGEN:108436",
          "NCIT:C4833",
          "ONCOTREE:OCSC",
          "Orphanet:502363",
          "SCTID:307502000",
          "UMLS:C0585362"
        ],
        "synonyms": [
          "mouth scc",
          "mouth squamous cell carcinoma",
          "oral cavity scc",
          "oral cavity squamous cell cancer",
          "oral cavity squamous cell carcinoma",
          "scc of mouth",
          "scc of oral cavity",
          "scc of the mouth",
          "scc of the oral cavity",
          "squamous cell carcinoma of mouth",
          "squamous cell carcinoma of oral cavity",
          "squamous cell carcinoma of the mouth",
          "squamous cell carcinoma of the oral cavity",
          "OCSC",
          "oral squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A squamous cell carcinoma arising from the oral cavity. It affects predominantly adults in their fifth and sixth decades of life and is associated with alcohol and tobacco use. Human papillomavirus is present in approximately half of the cases. It is characterized by a tendency to metastasize early to the lymph nodes. When the tumor is small, patients are often asymptomatic. Physical examination may reveal erythematous or white lesions or plaques. The majority of patients present with signs and symptoms of locally advanced disease including mucosal ulceration, pain, difficulty with speaking, chewing, and swallowing, bleeding, weight loss, and neck swelling. Patients may also present with swollen neck lymph nodes without any symptoms from the oropharyngeal tumor. The most significant prognostic factors are the size of the tumor and the lymph nodes status."
      },
      "child_count": 14,
      "reference_id": "MONDO:0004958"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6431,
      "label": "cheek mucosa cancer"
    },
    {
      "id": 6701,
      "label": "oral cavity squamous cell carcinoma"
    }
  ]
}