{
  "id": 20711,
  "label": "combined carcinoid and adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021659",
  "properties": {
    "xrefs": [
      "GARD:0005741",
      "ICDO:8244/3",
      "ICDO:8245/3",
      "MEDGEN:83124",
      "MESH:C538230",
      "NCIT:C4139",
      "UMLS:C0334302"
    ],
    "synonyms": [
      "adenocarcinoid neoplasm",
      "adenocarcinoid tumor",
      "adenocarcinoid tumour",
      "combined carcinoid and adenocarcinoma",
      "combined carcinoid neoplasm and adenocarcinoma",
      "combined carcinoid tumor and adenocarcinoma",
      "combined carcinoid tumour and adenocarcinoma",
      "composite carcinoid",
      "composite carcinoid neoplasm",
      "composite carcinoid tumor",
      "composite carcinoid tumour",
      "mixed carcinoid neoplasm",
      "mixed carcinoid tumor",
      "mixed carcinoid tumour"
    ],
    "definition": "A malignant epithelial neoplasm composed of a mixture of neuroendocrine cells with morphologic and immunohistochemical characteristics of carcinoid tumor and malignant glandular cells."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    }
  ],
  "children": [
    {
      "id": 18191,
      "label": "goblet cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4255,
        5155,
        16040,
        20711
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010414",
          "ICDO:8243/3",
          "MEDGEN:60007",
          "NCIT:C3689",
          "NORD:1931",
          "ONCOTREE:GCCAP",
          "Orphanet:329984",
          "UMLS:C0205695"
        ],
        "synonyms": [
          "GCC",
          "Goblet Cell Adenocarcinoma",
          "appendix adenocarcinoid tumor",
          "appendix adenocarcinoid tumour",
          "appendix goblet cell carcinoid",
          "appendix goblet cell carcinoid tumor",
          "appendix goblet cell carcinoid tumour",
          "appendix mixed carcinoid-adenocarcinoma",
          "carcinoma of goblet cell",
          "goblet cell adenocarcinoid",
          "goblet cell carcinoid",
          "goblet cell carcinoid of appendix",
          "goblet cell carcinoid of the appendix",
          "goblet cell carcinoid tumor",
          "goblet cell carcinoid tumour",
          "goblet cell carcinoma",
          "goblet cell tumor",
          "goblet cell tumour",
          "mucinous carcinoid tumor",
          "mucinous carcinoid tumour",
          "mucinous carcinoid"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive type of endocrine tumor of the appendix presenting equally in males and females in the fifth decade of life and manifesting with a palpable mass and abdominal pain or acute appendicitis. Metastasis to the ovaries, peritoneum or right colon has usually already occurred in half of patients at the time of diagnosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018017"
    }
  ],
  "roots": [
    {
      "id": 6734,
      "label": "carcinoma"
    }
  ]
}