{
  "id": 20751,
  "label": "acute rheumatic heart disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021777",
  "properties": {
    "xrefs": [
      "ICD9:391.8",
      "ICD9:391.9",
      "MEDGEN:19779",
      "NCIT:C34985",
      "SCTID:312591002",
      "UMLS:C0035440",
      "icd11.foundation:535094176"
    ],
    "synonyms": [
      "acute rheumatic heart disease",
      "Active rheumatic fever with heart involvement",
      "active rheumatic fever with heart involvement",
      "acute Rheumatic Heart Disease",
      "acute rheumatic carditis",
      "acute rheumatic fever with heart involvement"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Pancarditis, involving inflammation of the endocardium, myocardium, and epicardium. It results from an autoimmune reaction following an infection with Streptococcus pyogenes (Group A Streptococci)."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 8383,
      "label": "rheumatic heart disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6967,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050827",
          "EFO:1001161",
          "ICD9:398.90",
          "ICD9:398.99",
          "MEDGEN:20565",
          "MESH:D012214",
          "MedDRA:10062110",
          "NCIT:C34882",
          "SCTID:23685000",
          "UMLS:C0035439",
          "icd11.foundation:291726710"
        ],
        "synonyms": [
          "RHD",
          "disease, rheumatic heart",
          "heart disease, rheumatic",
          "rheumatic carditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "An autoinflammatory condition following an infection with Group A Beta Hemolytic Streptococcus (GABHS), in which the heart is attacked by antibodies formed in reaction to a recent GABHS infection. Chief anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords, all of which can result in valvular dysfunction."
      },
      "child_count": 8,
      "reference_id": "MONDO:0006955"
    },
    {
      "id": 20092,
      "label": "acute disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24492
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:1738",
          "MESH:D000208",
          "SCTID:2704003",
          "UMLS:C0001314"
        ],
        "synonyms": [
          "acute disease",
          "acute diseases",
          "disease, acute"
        ],
        "definition": "Disease having a short and relatively severe course."
      },
      "child_count": 119,
      "reference_id": "MONDO:0020683"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 8383,
      "label": "rheumatic heart disease"
    },
    {
      "id": 20092,
      "label": "acute disease"
    }
  ]
}