{
  "id": 20770,
  "label": "temporomandibular joint dysfunction syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0021895",
  "properties": {
    "xrefs": [
      "MEDGEN:21093",
      "MESH:D013706",
      "NCIT:C35066",
      "UMLS:C0039496"
    ],
    "synonyms": [
      "temporomandibular joint dysfunction syndrome",
      "Costen Syndrome",
      "Costen's Syndrome",
      "Costen's complex",
      "Costen's syndrome",
      "Costens Syndrome",
      "Joint Syndrome, Temporomandibular",
      "Mandibular dysfunction",
      "Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint",
      "Myofascial pain - dysfunction syndrome of TMJ",
      "Snapping jaw",
      "Syndrome, Costen's",
      "Syndrome, TMJ",
      "Syndrome, Temporomandibular Joint",
      "TMJ Syndrome",
      "TMJ syndrome",
      "TMJPDS - Temporomandibular joint pain dysfunction syndrome",
      "Temporomandibular Joint Dysfunction Syndrome",
      "Temporomandibular Joint Syndrome",
      "Temporomandibular joint pain dysfunction syndrome",
      "Temporomandibular joint syndrome",
      "Temporomandibular joint-pain-dysfunction syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      }
    ],
    "definition": "A common disorder noted with jaw movement. It may be caused by malocclusion, repetitive use injury, trauma or arthritis. It is more prevalent among females between their second and fourth decades. Clinical signs include preauricular pain, temporomandibular joint clicking (as the mandibular condyle slips from the articulation made with the capsular disk and temporal bone) and restriction of jaw motion. Clinical course is typically benign but may progress to associated headaches, ear and neck pain, tinnitus and dislocation of temporomandibular joint. Prognosis is favorable as a majority of cases will respond to conservative management."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    },
    {
      "id": 7131,
      "label": "temporomandibular joint disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8264
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0005279",
          "ICD9:524.60",
          "ICD9:524.69",
          "MEDGEN:21092",
          "MESH:D013705",
          "NCIT:C63709",
          "SCTID:41888000",
          "UMLS:C0039494"
        ],
        "synonyms": [
          "TMD"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Any condition affecting the anatomic and functional characteristics of the temporomandibular joint."
      },
      "child_count": 3,
      "reference_id": "MONDO:0005473"
    },
    {
      "id": 8304,
      "label": "myofascial pain syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7023
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:431",
          "EFO:1001054",
          "GARD:0024491",
          "ICD9:729.1",
          "MEDGEN:6496",
          "MESH:D009209",
          "MedDRA:10048780",
          "SCTID:24693007",
          "UMLS:C0027073"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Muscular pain in numerous body regions that can be reproduced by pressure on trigger points, localized hardenings in skeletal muscle tissue. Pain is referred to a location distant from the trigger points. A prime example is the temporomandibular joint dysfunction syndrome."
      },
      "child_count": 1,
      "reference_id": "MONDO:0006862"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4370,
      "label": "syndromic disease"
    },
    {
      "id": 7131,
      "label": "temporomandibular joint disorder"
    },
    {
      "id": 8304,
      "label": "myofascial pain syndrome"
    }
  ]
}