{
  "id": 20808,
  "label": "large-cell immunoblastic lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0022037",
  "properties": {
    "xrefs": [
      "GARD:0008219",
      "MEDGEN:86955",
      "MESH:D016400",
      "UMLS:C0079746"
    ],
    "synonyms": [
      "Diffuse Immunoblastic Lymphosarcoma",
      "Diffuse Immunoblastic Lymphosarcomas",
      "Diffuse non-Hodgkin lymphoma, immunoblastic",
      "Diffuse non-Hodgkin's immunoblastic (diffuse) lymphoma",
      "Diffuse non-Hodgkin's lymphoma, immunoblastic",
      "Diffuse non-Hodgkin's lymphoma, immunoblastic (clinical)",
      "IMMUNOBLASTIC LARGE LYMPHOMA",
      "Immunoblastic Large Cell Lymphoma",
      "Immunoblastic Large-Cell Lymphoma",
      "Immunoblastic Large-Cell Lymphomas",
      "Immunoblastic Lymphoma",
      "Immunoblastic Lymphoma, Large-Cell",
      "Immunoblastic Lymphomas, Large-Cell",
      "Immunoblastic Lymphosarcoma, Diffuse",
      "Immunoblastic Lymphosarcomas, Diffuse",
      "Immunoblastic Sarcoma",
      "Immunoblastic Sarcomas",
      "Immunoblastic malignant lymphoma - large cell",
      "Immunoblastoma",
      "Immunoblastomas",
      "LARGE IMMUNOBLASTIC LYMPHOMA",
      "LYMPHOMA IMMUNOBLASTIC LARGE",
      "LYMPHOMA LARGE IMMUNOBLASTIC",
      "Large Cell Immunoblastic Lymphoma",
      "Large cell immunoblastic lymphoma",
      "Large-Cell Immunoblastic Lymphoma",
      "Large-Cell Immunoblastic Lymphomas",
      "Large-Cell Lymphoma, Immunoblastic",
      "Large-Cell Lymphomas, Immunoblastic",
      "Lymphoma, Immunoblastic Large-Cell",
      "Lymphoma, Immunoblastic, Large Cell",
      "Lymphoma, Immunoblastic, Large-Cell",
      "Lymphoma, Large Cell, Immunoblastic",
      "Lymphoma, Large-Cell Immunoblastic",
      "Lymphoma, Large-Cell, Immunoblastic",
      "Lymphoma, immunoblastic, high grade",
      "Lymphomas, Immunoblastic Large-Cell",
      "Lymphomas, Large-Cell Immunoblastic",
      "Lymphosarcoma, Diffuse Immunoblastic",
      "Lymphosarcomas, Diffuse Immunoblastic",
      "Malignant lymphoma - immunoblastic",
      "Sarcoma, Immunoblastic",
      "Sarcomas, Immunoblastic"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Malignant lymphoma characterized by the presence of immunoblasts with uniformly round-to-oval nuclei, one or more prominent nucleoli, and abundant cytoplasm. This class may be subdivided into plasmacytoid and clear-cell types based on cytoplasmic characteristics. A third category, pleomorphous, may be analogous to some of the peripheral T-cell lymphomas (LYMPHOMA, T-CELL, PERIPHERAL) recorded in both the United States and Japan."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18836,
      "label": "non-Hodgkin lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060060",
          "EFO:0005952",
          "ICDO:9591/3",
          "MEDGEN:6160",
          "MESH:D008228",
          "MedDRA:10029547",
          "NCIT:C3211",
          "ONCOTREE:NHL",
          "Orphanet:547",
          "UMLS:C0024305"
        ],
        "synonyms": [
          "NHL",
          "non-Hodgkin lymphoma",
          "non-Hodgkin's lymphoma",
          "non-Hodgkin's lymphoma (NHL)",
          "non-Hodgkins lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage."
      },
      "child_count": 10,
      "reference_id": "MONDO:0018908"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18836,
      "label": "non-Hodgkin lymphoma"
    }
  ]
}