{
  "id": 20861,
  "label": "angiosarcoma of the scalp",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0022454",
  "properties": {
    "synonyms": [
      "angiosarcoma (disease) of scalp",
      "scalp angiosarcoma (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Angiosarcoma of the scalp is a rare cancer which most commonly affects the elderly. This condition is characterized by bruise-like lesions that escalate to elevated, nodular, or ulcerated tumors. Extensive local growth is common and metastasis to regional lymph nodes and to the lungs may occur. The cause of angiosarcoma of the scalp is unknown, although several associations have been reported, including lymphedema, prior radiation treatment, and environmental exposures. Treatment may include surgery, radiation and chemotherapy."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7266,
      "label": "head and neck cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7231
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11934",
          "EFO:0006859",
          "MEDGEN:78920",
          "NCIT:C4013",
          "UMLS:C0278996"
        ],
        "synonyms": [
          "head and neck neoplasm",
          "head and neck tumors",
          "head and neck tumours",
          "head/neck neoplasm",
          "tumour of head and neck",
          "cancer of craniocervical region",
          "cancer of head and neck",
          "cancer of the head and neck",
          "craniocervical region cancer",
          "head and neck cancer",
          "head and neck malignant neoplasia",
          "malignant craniocervical region neoplasm",
          "malignant head and neck neoplasm",
          "malignant head and neck tumor",
          "malignant head and neck tumour",
          "malignant neoplasm of craniocervical region",
          "malignant neoplasm of head and neck",
          "malignant neoplasm of the head and neck",
          "malignant tumor of head and neck",
          "malignant tumor of the head and neck",
          "malignant tumour of head and neck",
          "malignant tumour of the head and neck"
        ],
        "definition": "A primary or metastatic malignant neoplasm affecting the head and neck. Representative examples include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma."
      },
      "child_count": 32,
      "reference_id": "MONDO:0005627"
    },
    {
      "id": 17394,
      "label": "angiosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4233,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0001816",
          "EFO:0003968",
          "GARD:0020900",
          "HP:0200058",
          "ICD9:171.9",
          "ICDO:9120/3",
          "MEDGEN:42385",
          "MESH:D006394",
          "MedDRA:10002476",
          "NCIT:C3088",
          "ONCOTREE:ANGS",
          "Orphanet:263413",
          "SCTID:403977003",
          "UMLS:C0018923"
        ],
        "synonyms": [
          "angiosarcoma",
          "angiosarcoma (disease)",
          "blood vessel sarcoma",
          "hemangiosarcoma",
          "hemangiosarcoma, malignant",
          "malignant angioendothelioma",
          "malignant hemangioendothelioma",
          "sarcoma of blood vessel",
          "vascular sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A malignant tumor arising from the endothelial cells of the blood vessels. Microscopically, it is characterized by frequently open vascular anastomosing and branching channels. The malignant cells that line the vascular channels are spindle or epithelioid and often display hyperchromatic nuclei. Angiosarcomas most frequently occur in the skin and breast. Patients with long-standing lymphedema are at increased risk of developing angiosarcoma."
      },
      "child_count": 38,
      "reference_id": "MONDO:0016982"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7266,
      "label": "head and neck cancer"
    },
    {
      "id": 17394,
      "label": "angiosarcoma"
    }
  ]
}