{
  "id": 21125,
  "label": "eosinophilic pustular folliculitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0023076",
  "properties": {
    "xrefs": [
      "GARD:0008534",
      "ICD9:704.8",
      "MEDGEN:140800",
      "MESH:C535953",
      "SCTID:95333004",
      "UMLS:C0406305",
      "icd11.foundation:1653155576"
    ],
    "synonyms": [
      "EPF",
      "Ofuji disease",
      "Ofuji's disease",
      "eosinophilic folliculitis",
      "eosinophilic folliculitis, pustular"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "Eosinophilic pustular folliculitis (EPF) is a skin disorder characterized by recurring itchy, red or skin-colored bumps and pustules (bumps containing pus). The condition is named after the fact that skin biopsies of this disorder find eosinophils (a type of immune cell) around hair follicles. The papules mostly appear on the face, scalp, neck and trunk and may persist for weeks or months. EPF affects males more than females.There are several variants of EPF includingclassic eosinophilic pustular folliculitis (mainly occurring in adults in Japan); HIV-associated EPF, also referred to as immunosuppression-associated EPF; and infantile EPF (with onset from birth or within the first year of life). Whether these are distinct disorders rather than variants of one disorder is controversial, partly because the underlying cause of EFP is not known.Several treatments have been described with variable results, including various oral or topical medications and phototherapy. In patients with HIV-associated disease, antiretroviral therapy tends to greatly diminish symptoms or even eliminate the condition."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 8035,
      "label": "folliculitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4496,
        4924
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4409",
          "EFO:1000702",
          "ICD9:704.8",
          "MEDGEN:4752",
          "MESH:D005499",
          "NCIT:C94408",
          "SCTID:13600006",
          "UMLS:C0016436",
          "Wikipedia:Folliculitis"
        ],
        "synonyms": [
          "dermatitis of hair follicle",
          "hair follicle dermatitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Inflammation of the hair follicles. Causes include excessive perspiration, skin infections, and skin wounds."
      },
      "child_count": 8,
      "reference_id": "MONDO:0006552"
    },
    {
      "id": 8092,
      "label": "vesiculobullous skin disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6820
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2731",
          "EFO:1000774",
          "MEDGEN:20778",
          "MESH:D012872",
          "UMLS:C0037275"
        ],
        "synonyms": [
          "vesiculobullous skin disease",
          "Sneddon Wilkinson disease",
          "Sneddon-Wilkinson disease",
          "skin diseases, vesicular",
          "subcorneal pustular dermatoses",
          "subcorneal pustular dermatosis",
          "bullous dermatoses",
          "bullous skin disease",
          "bullous skin diseases",
          "dermatoses, bullous",
          "dermatoses, subcorneal pustular",
          "dermatoses, vesiculobullous",
          "dermatosis, subcorneal pustular",
          "pustular dermatoses, subcorneal",
          "pustular dermatosis, subcorneal",
          "skin disease, bullous",
          "skin disease, vesicular",
          "skin disease, vesiculobullous",
          "skin diseases, bullous",
          "vesicular skin disease",
          "vesicular skin diseases",
          "vesiculobullous dermatoses",
          "vesiculobullous skin diseases"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Skin diseases characterized by local or general distributions of blisters. They are classified according to the site and mode of blister formation. Lesions can appear spontaneously or be precipitated by infection, trauma, or sunlight. Etiologies include immunologic and genetic factors. (From Scientific American Medicine, 1990)"
      },
      "child_count": 8,
      "reference_id": "MONDO:0006617"
    }
  ],
  "children": [
    {
      "id": 25100,
      "label": "classic eosinophilic pustular folliculitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        21125
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022452",
          "Orphanet:617408"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0850048"
    }
  ],
  "roots": [
    {
      "id": 8035,
      "label": "folliculitis"
    },
    {
      "id": 8092,
      "label": "vesiculobullous skin disease"
    }
  ]
}