{
  "id": 21244,
  "label": "laryngeal papillomatosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0023597",
  "properties": {
    "xrefs": [
      "GARD:0006864",
      "MEDGEN:96006",
      "MESH:C537876",
      "NCIT:C157733",
      "SCTID:232457008",
      "UMLS:C0396072"
    ],
    "synonyms": [
      "laryngeal papillomatosis",
      "Warts in the throat",
      "juvenile laryngeal papillomatosis",
      "juvenile laryngeal papillomatosis (subtype)",
      "recurrent laryngeal papillomatosis",
      "recurrent laryngeal papillomatosis (subtype)"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      },
      {
        "ref": "MONDO:0024623",
        "name": "otorhinolaryngologic disease"
      }
    ],
    "definition": "Laryngeal papillomatosis is a form of recurrent respiratory papillomatosis where tumors (papillomas) grow in the larynx (voice box).Symptoms usually begin with hoarseness and/or a change in the voice.Some people mayexperience difficulty breathing (dyspnea) and/or experience other life-threatening complications if the papillomas block the airway. The tumors may vary in size and grow very quickly. They often grow back even when removed.Laryngeal papillomatosisis caused by two types of human papilloma virus (HPV), called HPV 6 and HPV 11."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4453,
      "label": "benign laryngeal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2881,
        20312
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2598",
          "ICD10CM:D14.1",
          "ICD9:212.1",
          "MEDGEN:56325",
          "NCIT:C3601",
          "SCTID:92175003",
          "UMLS:C0153952",
          "icd11.foundation:669823967"
        ],
        "synonyms": [
          "laryngeal tumor",
          "laryngeal tumour",
          "larynx neoplasm",
          "benign laryngeal neoplasm",
          "benign laryngeal tumor",
          "benign laryngeal tumour",
          "benign larynx neoplasm",
          "benign larynx tumor",
          "benign larynx tumour",
          "benign neoplasm of larynx",
          "benign neoplasm of the larynx",
          "benign tumor of larynx",
          "benign tumor of the larynx",
          "benign tumour of larynx",
          "benign tumour of the larynx",
          "laryngeal neoplasm, benign",
          "larynx benign neoplasm",
          "laryngeal benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm that arises from the larynx. Representative examples include squamous papilloma and hemangioma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0002354"
    },
    {
      "id": 4462,
      "label": "papilloma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20336,
        22952
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2615",
          "ICDO:8050/0",
          "MEDGEN:10566",
          "MESH:D010212",
          "NCIT:C7440",
          "SCTID:711329002",
          "UMLS:C0030354"
        ],
        "synonyms": [
          "papilloma",
          "papilloma (except papilloma of bladder M-81201) (morphologic abnormality)",
          "papilloma, benign",
          "papillomatosis NOS (morphologic abnormality)"
        ],
        "definition": "A benign epithelial neoplasm that projects above the surrounding epithelial surface and consists of villous or arborescent outgrowths of fibrovascular stroma."
      },
      "child_count": 28,
      "reference_id": "MONDO:0002363"
    },
    {
      "id": 18877,
      "label": "recurrent respiratory papillomatosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6815,
        7231,
        20338,
        21538
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000111",
          "ICD9:078.19",
          "MEDGEN:216998",
          "MESH:C535297",
          "MedDRA:10059314",
          "NCIT:C128637",
          "NORD:1651",
          "Orphanet:60032",
          "SCTID:472827002",
          "UMLS:C1168198",
          "icd11.foundation:151039887"
        ],
        "synonyms": [
          "RRP",
          "recurrent respiratory papillomatosis",
          "AORRP (type)",
          "JORRP (type)",
          "adult-onset recurrent respiratory papillomatosis (type)",
          "juvenile laryngeal papilloma",
          "juvenile-onset recurrent respiratory papillomatosis (type)",
          "laryngeal papilloma, recurrent",
          "respiratory papillomatosis, recurrent"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "Recurrent respiratory papillomatosis is a rare respiratory disease characterized by the development of exophytic papillomas, affecting the mucosa of the upper aero-digestive tract (with a strong predilection for the larynx), caused by an infection with human papilloma virus. Symptoms at presentation may include hoarseness, chronic cough, dyspnea, recurrent upper respiratory infections, pneumonia, dysphagia, stridor, and/or failure to thrive."
      },
      "child_count": 4,
      "reference_id": "MONDO:0018955"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4453,
      "label": "benign laryngeal neoplasm"
    },
    {
      "id": 4462,
      "label": "papilloma"
    },
    {
      "id": 18877,
      "label": "recurrent respiratory papillomatosis"
    }
  ]
}