{
  "id": 21255,
  "label": "lipodermatosclerosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0023646",
  "properties": {
    "xrefs": [
      "GARD:0009671",
      "MEDGEN:140802",
      "MESH:C537026",
      "SCTID:410016009",
      "UMLS:C0406500",
      "icd11.foundation:473315619"
    ],
    "synonyms": [
      "acute lipodermatosclerosis",
      "hypodermitis sclerodermaformis",
      "sclerosing panniculitis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "Lipodermatosclerosis refers to changes in the skin of the lower legs. It is a form of panniculitis (inflammation of the layer of fat under the skin). Signs and symptoms include pain, hardening of skin, change in skin color (redness), swelling, and a tapering of the legs above the ankles. The exact underlying cause is unknown; however, it appears to be associated with venous insufficiency and/or obesity. Treatment usually includes compression therapy."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4496,
      "label": "dermatitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6820,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2723",
          "ICD9:692.9",
          "MEDGEN:849741",
          "MESH:D003872",
          "NCIT:C2983",
          "SCTID:43116000",
          "UMLS:C3875321"
        ],
        "synonyms": [
          "inflammation of skin",
          "inflammation of the skin",
          "inflammation of zone of skin",
          "inflammatory skin disease",
          "skin inflammation",
          "zone of skin inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An inflammatory process affecting the skin. Signs include red rash, itching, and blister formation. Representative examples are contact dermatitis, atopic dermatitis, and seborrheic dermatitis."
      },
      "child_count": 66,
      "reference_id": "MONDO:0002406"
    },
    {
      "id": 8067,
      "label": "panniculitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4198,
        5762,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1526",
          "EFO:1000746",
          "ICD9:729.3",
          "ICD9:729.30",
          "ICD9:729.39",
          "MEDGEN:45301",
          "MESH:D015434",
          "NCIT:C33645",
          "SCTID:22125009",
          "UMLS:C0030326",
          "Wikipedia:Panniculitis",
          "icd11.foundation:1056888958"
        ],
        "synonyms": [
          "Subcutaneous adipose tissue",
          "Subcutaneous tissue",
          "inflammation of subcutaneous adipose tissue",
          "subcutaneous adipose tissue inflammation",
          "subcutis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Inflammation of the subcutaneous adipose tissue."
      },
      "child_count": 18,
      "reference_id": "MONDO:0006591"
    },
    {
      "id": 19369,
      "label": "localized scleroderma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19180
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8472",
          "EFO:1001361",
          "GARD:0007058",
          "ICD10CM:L94.0",
          "ICD9:701.0",
          "MEDGEN:48586",
          "MESH:D012594",
          "MedDRA:10039712",
          "NCIT:C72069",
          "Orphanet:90289",
          "SCTID:201048007",
          "UMLS:C0036420",
          "icd11.foundation:1430740369"
        ],
        "synonyms": [
          "circumscribed scleroderma",
          "localised fibrosing scleroderma",
          "localised scleroderma (disorder) [ambiguous]",
          "localized fibrosing scleroderma",
          "localized morphoea",
          "localized scleroderma",
          "localized scleroderma (disorder) [ambiguous]",
          "morphea",
          "Scleroderma, localised",
          "Scleroderma, localized"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Localized scleroderma is the skin localized form of scleroderma characterized by fibrosis of the skin causing cutaneous plaques or strips."
      },
      "child_count": 2,
      "reference_id": "MONDO:0019562"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4496,
      "label": "dermatitis"
    },
    {
      "id": 8067,
      "label": "panniculitis"
    },
    {
      "id": 19369,
      "label": "localized scleroderma"
    }
  ]
}