{
  "id": 21294,
  "label": "congenital anomaly of cardiovascular system",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024239",
  "properties": {
    "xrefs": [
      "ICD9:747.89",
      "ICD9:747.9",
      "MEDGEN:777113",
      "NCIT:C35729",
      "SCTID:9904008",
      "UMLS:C3665496"
    ],
    "synonyms": [
      "cardiovascular system development disease",
      "congenital Abnormality of the circulatory system",
      "congenital anomaly of cardiovascular system",
      "congenital cardiovascular Abnormality",
      "congenital cardiovascular anomaly",
      "disorder of cardiovascular system development",
      "congenital cardiovascular disorder"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A disease that has its basis in the disruption of cardiovascular system development."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 6736,
      "label": "cardiovascular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1287",
          "EFO:0000319",
          "ICD10CM:I00-I99",
          "ICD9:390-459",
          "ICD9:420-429",
          "ICD9:423",
          "ICD9:423.8",
          "ICD9:424",
          "ICD9:429",
          "ICD9:429.2",
          "ICD9:429.7",
          "ICD9:429.8",
          "ICD9:429.81",
          "ICD9:429.89",
          "ICD9:459.89",
          "ICD9:459.9",
          "MEDGEN:2848",
          "MESH:D002318",
          "NANDO:1100005",
          "NCIT:C2931",
          "SCTID:49601007",
          "UMLS:C0007222",
          "icd11.foundation:424293435",
          "icd11.foundation:426429380"
        ],
        "synonyms": [
          "cardiovascular disease",
          "cardiovascular disease (CVD)",
          "cardiovascular disorder",
          "cardiovascular system disease",
          "cardiovascular system disease or disorder",
          "disease of cardiovascular system",
          "disease or disorder of cardiovascular system",
          "disorder of cardiovascular system",
          "circulatory system disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease involving the cardiovascular system."
      },
      "child_count": 6,
      "reference_id": "MONDO:0004995"
    },
    {
      "id": 20383,
      "label": "disorder of development or morphogenesis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:Q00-Q99",
          "MEDGEN:1843482",
          "UMLS:C0694457"
        ],
        "definition": "Any disease or disorder that disrupts the process development of an anatomical structure. Can be due to genetic or environmental causes. Typically happens during embryogenesis, but also includes post-embryonic development."
      },
      "child_count": 190,
      "reference_id": "MONDO:0021147"
    }
  ],
  "children": [
    {
      "id": 5069,
      "label": "venous hemangioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7994,
        21294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:467",
          "ICD9:228.09",
          "ICDO:9122/0",
          "MEDGEN:90801",
          "NCIT:C4296",
          "SCTID:403968005",
          "UMLS:C0334532"
        ],
        "synonyms": [
          "Venous angioma",
          "Venous malformation"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A rare slow growing benign tumor of aberrant and ectatic venous connections."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003083"
    },
    {
      "id": 7116,
      "label": "congenital heart disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6967,
        21294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1682",
          "EFO:0005207",
          "ICD9:746.84",
          "ICD9:746.89",
          "ICD9:746.9",
          "MEDGEN:57501",
          "MESH:D006330",
          "NCIT:C95834",
          "SCTID:13213009",
          "UMLS:C0152021",
          "icd11.foundation:2004408087"
        ],
        "synonyms": [
          "heart malformation",
          "congenital anomaly of heart",
          "congenital heart defect",
          "congenital heart defects",
          "Abnormality, heart",
          "abnormalities, heart",
          "defect, congenital heart",
          "defects, congenital heart",
          "heart abnormalities",
          "heart abnormality",
          "heart defect, congenital",
          "heart, malformation Of"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A heart disease that is present at birth. Representative examples include atrial septal defect, ventricular septal defect, tetralogy of Fallot, and patent foramen ovale."
      },
      "child_count": 46,
      "reference_id": "MONDO:0005453"
    },
    {
      "id": 19327,
      "label": "congenital heart malformation",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0005269",
          "MEDGEN:1680993",
          "Orphanet:88991",
          "UMLS:C3649636"
        ],
        "synonyms": [
          "congenital heart malformation",
          "disorder of heart development",
          "heart development disease",
          "congenital non-syndromic heart malformation",
          "rare congenital non-syndromic heart malformation"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease that has its basis in the disruption of heart development."
      },
      "child_count": 26,
      "reference_id": "MONDO:0019512"
    },
    {
      "id": 19779,
      "label": "congenital arteriovenous fistula",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019560",
          "MEDGEN:137676",
          "MESH:D001164",
          "MedDRA:10003226",
          "NCIT:C35377",
          "Orphanet:98731",
          "SCTID:234148007",
          "UMLS:C0332965"
        ],
        "synonyms": [
          "congenital arteriovenous shunt"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A congenital vascular disorder characterized byan abnormal connection between an artery and a vein, appearing as varicose veins with port wine discoloration, leading to a bypass of the capillary bed. Signs and symptoms include palpable continuous thrill in the dilated vessels, continuous machinery murmur with systolic accentuation, collapsing arterial pulse, Nicoladoni Branham sign, as well as local gigantism and hot ulcers due to hypoxia, among others."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020296"
    },
    {
      "id": 20856,
      "label": "persistent fetal circulation syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        21294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001103",
          "GARD:0027905",
          "ICD10CM:P29.3",
          "MEDGEN:45824",
          "MESH:D010547",
          "NCIT:C85006",
          "SCTID:206597007",
          "SCTID:233815004",
          "SCTID:35604006",
          "UMLS:C0031190",
          "icd11.foundation:346808536"
        ],
        "synonyms": [
          "PPHN",
          "persistent fetal circulation",
          "persistent foetal circulation",
          "persistent pulmonary hypertension of the newborn"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A cardiopulmonary disorder characterized by systemic arterial hypoxemia secondary to pulmonary hypertension and extrapulmonary right to left shunting across the foramen ovale and ductus arteriosus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0022430"
    }
  ],
  "roots": [
    {
      "id": 6736,
      "label": "cardiovascular disorder"
    },
    {
      "id": 20383,
      "label": "disorder of development or morphogenesis"
    }
  ]
}