{
  "id": 21328,
  "label": "skin disorder caused by infection",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024294",
  "properties": {
    "xrefs": [
      "MESH:D012874"
    ],
    "synonyms": [
      "disease, infectious skin",
      "diseases, infectious skin",
      "infectious skin disease",
      "infectious skin diseases",
      "skin disease, infectious"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "Skin diseases caused by bacteria, fungi, parasites, or viruses."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 15,
  "parents": [
    {
      "id": 6820,
      "label": "skin disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4198
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:37",
          "EFO:0000701",
          "ICD9:702",
          "ICD9:702.8",
          "ICD9:709.8",
          "MEDGEN:20777",
          "MESH:D012871",
          "NANDO:2100281",
          "NCIT:C3371",
          "SCTID:95320005",
          "UMLS:C0037274"
        ],
        "synonyms": [
          "cutaneous disorder",
          "disease of zone of skin",
          "disease or disorder of zone of skin",
          "disorder of skin",
          "disorder of zone of skin",
          "skin diseases and manifestations",
          "skin disorder",
          "zone of skin disease",
          "zone of skin disease or disorder",
          "dermatosis",
          "genodermatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs."
      },
      "child_count": 72,
      "reference_id": "MONDO:0005093"
    },
    {
      "id": 7200,
      "label": "infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050117",
          "EFO:0005741",
          "ICD10CM:A00-B99",
          "ICD9:079.0",
          "ICD9:136.8",
          "ICD9:136.9",
          "IDO:0000436",
          "MEDGEN:1057",
          "MESH:D003141",
          "NCIT:C26726",
          "SCTID:40733004",
          "UMLS:C0009450"
        ],
        "synonyms": [
          "communicable disease",
          "infection",
          "infectious",
          "infectious disease",
          "infectious diseases and manifestations",
          "infectious disorder",
          "transmissible disease",
          "clinical infection",
          "disease by infectious agent"
        ],
        "definition": "A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact."
      },
      "child_count": 35,
      "reference_id": "MONDO:0005550"
    }
  ],
  "children": [
    {
      "id": 2816,
      "label": "Epstein-Barr virus hepatitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6837,
        7602,
        21328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050204",
          "MEDGEN:640194",
          "SCTID:302919001",
          "UMLS:C0554114"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A viral hepatitis that results in inflammation, located in liver, has material basis in Human herpesvirus 4 and has symptom headache, has symptom fatigue, has symptom fever, has symptom abdominal pain, has symptom nausea, and has symptom jaundice."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000286"
    },
    {
      "id": 2851,
      "label": "exanthema subitum",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6834,
        8030,
        21328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050495",
          "EFO:1001320",
          "ICD10CM:B08.2",
          "ICD9:057.8",
          "ICD9:058.1",
          "ICD9:058.10",
          "MEDGEN:41909",
          "MESH:D005077",
          "NCIT:C128420",
          "SCTID:54385001",
          "UMLS:C0015231",
          "icd11.foundation:1883970802"
        ],
        "synonyms": [
          "exanthem subitum",
          "roseola",
          "roseola Infantum",
          "sixth disease",
          "pseudorubella"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An infection that is due to human herpesvirus (HHV) types 6 or 7; it is characterized by 3-5 days of high fever followed by the acute onset of a rosy, pink, non-pruritic, macular rash that is predominantly on the neck and trunk."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000337"
    },
    {
      "id": 2852,
      "label": "variola major infectious disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6437,
        8030,
        21328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050508",
          "ICD9:050.0",
          "MEDGEN:740750",
          "SCTID:47452006",
          "UMLS:C1812609"
        ],
        "synonyms": [
          "variola major"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0000338"
    },
    {
      "id": 3449,
      "label": "common wart",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6834,
        21328,
        21573
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11165",
          "EFO:0009662",
          "ICD10CM:B07",
          "ICD9:078.1",
          "ICD9:078.10",
          "ICD9:078.19",
          "MEDGEN:777120",
          "MESH:D014860",
          "NCIT:C27087",
          "SCTID:57019003",
          "UMLS:C3665596",
          "icd11.foundation:1074706780"
        ],
        "synonyms": [
          "common wart",
          "verruca vulgaris",
          "viral Warts",
          "viral Warts due to papilloma virus",
          "viral wart",
          "wart"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A wart caused by human papillomavirus. It can appear anywhere on the skin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001209"
    },
    {
      "id": 3979,
      "label": "plantar wart",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        21328,
        21573,
        24062
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13775",
          "EFO:1002023",
          "ICD10CM:B07.0",
          "ICD9:078.12",
          "MEDGEN:53003",
          "NCIT:C26913",
          "SCTID:63440008",
          "UMLS:C0042548"
        ],
        "synonyms": [
          "plantar wart",
          "verruca plantaris"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A wart in the plantar surface of the foot. It is caused by human papillomavirus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001795"
    },
    {
      "id": 6405,
      "label": "herpetic whitlow",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6399,
        7501,
        21328,
        21440
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8607",
          "ICD9:054.6",
          "MEDGEN:509122",
          "NCIT:C128402",
          "SCTID:43891009",
          "UMLS:C0153042"
        ],
        "synonyms": [
          "Simplexvirus caused paronychia (disease)",
          "Simplexvirus paronychia (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A painful blister of the periungual skin that is caused by herpes simplex virus type 1 or 2."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004616"
    },
    {
      "id": 7250,
      "label": "herpes zoster",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7249,
        8092,
        20721,
        21328,
        24063
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8536",
          "EFO:0006510",
          "ICD10CM:B02",
          "ICD9:053",
          "MEDGEN:42437",
          "MESH:D006562",
          "NCIT:C71079",
          "SCTID:4740000",
          "UMLS:C0019360"
        ],
        "synonyms": [
          "Zoster",
          "herpes Zoster",
          "shingles",
          "postherpetic neuralgia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A common dermal and neurologic disorder caused by reactivation of the varicella-zoster virus that has remained dormant within dorsal root ganglia, often for decades, after the patient's initial exposure to the virus in the form of varicella (chickenpox). It is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area."
      },
      "child_count": 15,
      "reference_id": "MONDO:0005609"
    },
    {
      "id": 7331,
      "label": "chickenpox",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7249,
        8092,
        21328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8659",
          "EFO:0007204",
          "ICD10CM:B01",
          "ICD9:052",
          "ICD9:052.9",
          "MEDGEN:2995",
          "MESH:D002644",
          "NCIT:C97132",
          "SCTID:38907003",
          "UMLS:C0008049"
        ],
        "synonyms": [
          "Varicella",
          "chicken pox",
          "chicken pox infection",
          "chickenpox",
          "varicella"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rash, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005700"
    },
    {
      "id": 7399,
      "label": "hand, foot and mouth disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7349,
        21328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10881",
          "EFO:0007294",
          "ICD10CM:B08.4",
          "ICD9:074.3",
          "MEDGEN:42330",
          "MESH:D006232",
          "NCIT:C128439",
          "SCTID:266108008",
          "UMLS:C0018572"
        ],
        "synonyms": [
          "HFMD",
          "hand foot and mouth disease",
          "hand, foot, and mouth disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A clinical syndrome that is usually caused by enterovirus infection, and that is characterized by fever, anorexia, and painful sores in the mouth, distal extremities, and/or other sites, including the buttocks."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005779"
    },
    {
      "id": 8094,
      "label": "viral exanthem",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8030,
        21328,
        24062
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8672",
          "EFO:1000776",
          "ICD9:057.8",
          "ICD9:057.9",
          "MEDGEN:509133",
          "SCTID:49882001",
          "UMLS:C0153062"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A virus-induced exanthem"
      },
      "child_count": 3,
      "reference_id": "MONDO:0006619"
    },
    {
      "id": 16966,
      "label": "virus-associated trichodysplasia spinulosa",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6834,
        21328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020592",
          "MEDGEN:1432798",
          "Orphanet:228379",
          "UMLS:C3267126"
        ],
        "synonyms": [
          "Cyclosporine-induced folliculodystrophy",
          "TS",
          "VATS",
          "pilomatrix dysplasia",
          "trichodysplasia spinulosa"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Virus-associated trichodysplasia spinulosa is a rare infectious skin disease characterized by the development of follicular papules with keratin spicules in various parts of the body, predominantly in the face (e.g. nose, eyebrows, auricles), that is due to polyomavirus infection in immunocompromized patients."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016455"
    },
    {
      "id": 17645,
      "label": "infective dermatitis associated with HTLV-1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6834,
        21328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021135",
          "MEDGEN:895843",
          "NCIT:C129260",
          "Orphanet:289347",
          "UMLS:C4274291"
        ],
        "synonyms": [
          "IDH",
          "IDH Gene family",
          "infective dermatitis associated with human T-lymphotropic virus type 1",
          "infective dermatitis associated with human T-lymphotropic virus type I",
          "isocitrate dehydrogenase Gene family"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A rare and severe chronic disease characterized by recurrent chronic eczema (with erythematous, scaly and crusted lesions) mainly affecting seborrheic areas (e.g. scalp, forehead, eyelids, paranasal and periauricular skin, neck, axillae, and groin), a generalized fine papular rash, chronic nasal discharge with crusting of the anterior nares, and non-virulent Staphylococcus aureus or beta-hemolytic Streptococcus infections, thought to be a result of HTLV-1-induced immunosuppression. Lymphadenopathy, anemia, mild to moderate pruritus and increased incidence of other infections (e.g. crusted scabies) have also been reported in some patients. Patients may subsequently develop other HTLV-1 associated conditions such as adult T-cell leukemia/lymphoma and tropical spastic paraparesis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017326"
    },
    {
      "id": 20419,
      "label": "skin infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4496,
        21328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:52365",
          "NCIT:C35025",
          "SCTID:19824006",
          "UMLS:C0037278"
        ],
        "synonyms": [
          "skin infection"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An inflammatory process affecting the skin, caused by bacteria, viruses, parasites, or fungi. Examples of bacterial infection include carbuncles, furuncles, impetigo, erysipelas, and abscesses. Examples of viral infection include shingles, warts, molluscum contagiosum, and pityriasis rosea. Examples of parasitic infection include scabies and lice. Examples of fungal infection include athlete's foot, yeast infection, and ringworm."
      },
      "child_count": 28,
      "reference_id": "MONDO:0021201"
    },
    {
      "id": 21329,
      "label": "skin disease caused by bacterial infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839,
        21328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MESH:D017192"
        ],
        "synonyms": [
          "Bacteria caused skin disease caused by infection",
          "Bacteria skin disease caused by infection",
          "bacterial skin disease",
          "bacterial skin diseases",
          "disease, bacterial skin",
          "diseases, bacterial skin",
          "skin disease, bacterial"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Skin diseases caused by bacteria."
      },
      "child_count": 34,
      "reference_id": "MONDO:0024295"
    },
    {
      "id": 21525,
      "label": "parasitic skin disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6859,
        21328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:20780",
          "MESH:D012876",
          "UMLS:C0037280"
        ],
        "synonyms": [
          "parasitic skin disease",
          "disease, parasitic skin",
          "diseases, parasitic skin",
          "parasitic skin diseases",
          "skin disease, parasitic"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Skin diseases caused by ARTHROPODS; HELMINTHS; or other parasites."
      },
      "child_count": 12,
      "reference_id": "MONDO:0024610"
    }
  ],
  "roots": [
    {
      "id": 6820,
      "label": "skin disorder"
    },
    {
      "id": 7200,
      "label": "infectious disease"
    }
  ]
}