{
  "id": 21330,
  "label": "vascular neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024296",
  "properties": {
    "xrefs": [
      "MEDGEN:129202",
      "NCIT:C7388",
      "UMLS:C0282607"
    ],
    "synonyms": [
      "neoplasm of vascular system",
      "neoplasm of vascular tissue",
      "neoplasms, vascular",
      "tumor of vascular system",
      "tumor of vascular tissue",
      "tumors, vascular",
      "tumour of vascular system",
      "tumour of vascular tissue",
      "vascular neoplasm",
      "vascular neoplasms",
      "vascular system neoplasm",
      "vascular system neoplasm (disease)",
      "vascular system tumor",
      "vascular system tumour",
      "vascular tissue neoplasm",
      "vascular tissue tumor",
      "vascular tissue tumour",
      "vascular tumor",
      "vascular tumors",
      "vascular tumour",
      "vascular tumours"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A benign, intermediate, or malignant neoplasm arising from vascular tissue including arteries, veins, venous sinuses, lymphatic vessels, arterioles and capillaries. It may occur in essentially any body location and is characterized by the presence of vascular channel formation and endothelial cells."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 16,
  "parents": [
    {
      "id": 21585,
      "label": "cardiovascular neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736,
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:105422",
          "NCIT:C4784",
          "SCTID:721573003",
          "UMLS:C0497243"
        ],
        "synonyms": [
          "cardiovascular neoplasm",
          "cardiovascular system neoplasm",
          "cardiovascular system tumor",
          "cardiovascular system tumour",
          "cardiovascular tumor",
          "cardiovascular tumour",
          "neoplasm of cardiovascular system",
          "tumor of cardiovascular system",
          "tumour of cardiovascular system"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the heart and/or vessels. Representative examples of benign neoplasms include atrial myxoma, hemangioma, and lymphangioma. Representative examples of malignant neoplasms include pericardial malignant mesothelioma and angiosarcoma."
      },
      "child_count": 10,
      "reference_id": "MONDO:0024757"
    }
  ],
  "children": [
    {
      "id": 4939,
      "label": "intravascular angioleiomyoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3034,
        8118,
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4266",
          "MEDGEN:233577",
          "NCIT:C5355",
          "UMLS:C1334267"
        ],
        "synonyms": [
          "intravascular angioleiomyoma",
          "intravascular angiomyoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A morphologic variant of angioleiomyoma characterized by the adherence of neoplastic smooth muscle cells to the walls of vascular channels."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002934"
    },
    {
      "id": 8529,
      "label": "hereditary neurocutaneous angioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19507,
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000676",
          "MEDGEN:226898",
          "OMIM:106070",
          "Orphanet:1062",
          "UMLS:C1275084",
          "icd11.foundation:182579434"
        ],
        "synonyms": [
          "hereditary neurocutaneous angioma",
          "angioma hereditary neurocutaneous",
          "angioma, hereditary neurocutaneous",
          "hemangiomatosis, disseminated",
          "hereditary neurocutaneous malformation",
          "spinal arterial Venous malformations with cutaneous hemangiomas"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Hereditary neurocutaneous angioma is characterized by the association of cerebral and cutaneous angiomatous lesions. It has been described in less than 10 families. Clinical manifestations of the cerebral lesions include epilepsy, cerebral hemorrhage, and focal neurological deficit. Transmission is autosomal dominant."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007116"
    },
    {
      "id": 16811,
      "label": "diffuse neonatal hemangiomatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0001861",
          "MEDGEN:96888",
          "Orphanet:2123",
          "SCTID:254782003",
          "UMLS:C0474965"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Diffuse neonatal hemangiomatosis is a rare vascular tumor from unknown origin characterized by multiple, progressive, rapidly growing cutaneous hemangiomas (e.g. in the scalp, face, trunk and extremities) associated with widespread visceral hemangiomas in the liver, lungs, gastrointestinal tract, brain, and meninges."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016237"
    },
    {
      "id": 18176,
      "label": "inverse Klippel-Trenaunay syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021488",
          "Orphanet:329324"
        ],
        "synonyms": [
          "cutaneous hemangioma with muscle or bone atrophy",
          "inverse Klippel-Trénaunay syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018001"
    },
    {
      "id": 18293,
      "label": "vasoproliferative tumor of retina",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3034,
        4419,
        20575,
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021533",
          "MEDGEN:1652844",
          "Orphanet:353356",
          "UMLS:C4749792"
        ],
        "synonyms": [
          "VPTR",
          "retinal vasoproliferative tumor",
          "retinal vasoproliferative tumour",
          "vasoproliferative tumor of ocular fundus",
          "vasoproliferative tumor of the ocular fundus",
          "vasoproliferative tumour of ocular fundus",
          "vasoproliferative tumour of the ocular fundus",
          "vasoproliferative tumor of the retina",
          "vasoproliferative tumour of the retina"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Vasoproliferative tumor of the retina is a rare, benign, retinal vascular disease characterized by solitary or multiple, unilateral or bilateral, intra-retinal tumor(s), usually located in the peripheral infero-temporal quadrant, and often associated with sub- and intraretinal exudates, epiretinal membranes, exudative retinal detachment and cystoid macular edema, as well as, occasionally, retinal and vitreous hemorrhage. Patients may present with visual loss, floaters, and/or photopsia. Association with various conditions, such as retinitis pigmentosa, congenital retinal toxoplasmosis, retinopathy of prematurity, or coloboma, has been reported."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018148"
    },
    {
      "id": 18706,
      "label": "kaposiform lymphangiomatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0013451",
          "MEDGEN:1807991",
          "Orphanet:464329",
          "UMLS:C5681097",
          "icd11.foundation:1139222402"
        ],
        "synonyms": [
          "KLA"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A generalized lymphatic anomaly characterized by kaposiform spindled lymphatic endothelial cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018736"
    },
    {
      "id": 18987,
      "label": "retinal capillary malformation",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19767,
        20441,
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018908",
          "Orphanet:71213"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Retinal cavernous hemangioma is a rare, benign, usually unilateral retinal vascular hamartoma that in most cases is asymptomatic but in some patients may present with blurred vision or floaters and that is characterized by the presence of grape-like vacuoles."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019101"
    },
    {
      "id": 19219,
      "label": "pelvis syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        16089,
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019045",
          "MEDGEN:1374037",
          "Orphanet:83628",
          "SCTID:725138002",
          "UMLS:C4510867",
          "icd11.foundation:1311821224"
        ],
        "synonyms": [
          "LUMBAR syndrome",
          "Lower body hemangioma-urogenital anomalies-myelopathy-bony deformities-anorectal and arterial malformations-renal anomalies syndrome",
          "SACRAL syndrome",
          "perineal hemangioma-external genitalia malformations-lipomyelomeningocele-vesicorenal abnormalities-imperforate anus syndrome",
          "urorectal septum malformation sequence"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "PELVIS is an acronym defining the association of Perineal hemangioma, External genitalia malformations, Lipomyelomeningocele, Vesicorenal abnormalities, Imperforate anus, and Skin tag. Eleven cases have been reported."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019388"
    },
    {
      "id": 20321,
      "label": "blood vessel neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7065,
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1651181",
          "NCIT:C7387",
          "SCTID:126736007",
          "UMLS:C4722524"
        ],
        "synonyms": [
          "blood vessel neoplasm",
          "blood vessel neoplasm (disease)",
          "blood vessel tumor",
          "blood vessel tumour",
          "neoplasm of blood vessel",
          "tumor of blood vessel",
          "tumour of blood vessel"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A neoplasm arising from arteries or veins."
      },
      "child_count": 10,
      "reference_id": "MONDO:0021080"
    },
    {
      "id": 20462,
      "label": "choroid neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4072,
        20436,
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:3059",
          "NCIT:C2949",
          "UMLS:C0008523"
        ],
        "synonyms": [
          "choroid tumor",
          "choroid tumour",
          "choroidal neoplasm",
          "choroidal tumor",
          "choroidal tumour",
          "neoplasm of choroid",
          "neoplasm of optic choroid",
          "neoplasm of the choroid",
          "optic choroid neoplasm",
          "optic choroid neoplasm (disease)",
          "optic choroid tumor",
          "optic choroid tumour",
          "tumor of choroid",
          "tumor of optic choroid",
          "tumor of the choroid",
          "tumour of choroid",
          "tumour of optic choroid",
          "tumour of the choroid"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A neoplasm (disease) that involves the optic choroid."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021258"
    },
    {
      "id": 21452,
      "label": "vascular bone neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18958,
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025402",
          "MEDGEN:234986",
          "NCIT:C6478",
          "UMLS:C1336946"
        ],
        "synonyms": [
          "bone vascular neoplasm",
          "bone vascular tumor",
          "bone vascular tumour",
          "osseous vascular neoplasm",
          "osseous vascular tumor",
          "osseous vascular tumour",
          "vascular bone neoplasm",
          "vascular neoplasm of bone",
          "vascular neoplasm of the bone",
          "vascular tumor of bone",
          "vascular tumor of the bone",
          "vascular tumour of bone",
          "vascular tumour of the bone"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A benign, intermediate, or malignant vascular neoplasm that arises from the bone."
      },
      "child_count": 8,
      "reference_id": "MONDO:0024499"
    },
    {
      "id": 22949,
      "label": "lymphatic vessel neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7065,
        7447,
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1857625",
          "NCIT:C3723",
          "UMLS:C2103272"
        ],
        "synonyms": [
          "lymph vessel neoplasm",
          "lymph vessel tumor",
          "lymph vessel tumour",
          "lymphatic vessel neoplasm",
          "lymphatic vessel tumor",
          "lymphatic vessel tumour",
          "neoplasm of lymph vessel",
          "neoplasm of lymphatic vessel",
          "neoplasm of the lymph vessel",
          "neoplasm of the lymphatic vessel",
          "tumor of lymph vessel",
          "tumor of lymphatic vessel",
          "tumor of the lymph vessel",
          "tumor of the lymphatic vessel",
          "tumour of lymph vessel",
          "tumour of lymphatic vessel",
          "tumour of the lymph vessel",
          "tumour of the lymphatic vessel"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm arising from the lymphatic vessels."
      },
      "child_count": 3,
      "reference_id": "MONDO:0036870"
    },
    {
      "id": 23428,
      "label": "benign choroid plexus neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3034,
        17175,
        20573,
        21330,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025906",
          "MEDGEN:87549",
          "NCIT:C8405",
          "SCTID:254943007",
          "UMLS:C0346290",
          "icd11.foundation:1168753028"
        ],
        "synonyms": [
          "benign choroid plexus neoplasm",
          "benign choroid plexus neoplasms",
          "benign choroid plexus tumor",
          "benign choroid plexus tumors",
          "benign choroid plexus tumour",
          "benign choroid plexus tumours",
          "benign neoplasm of choroid plexus",
          "benign neoplasm of the choroid plexus",
          "benign tumor of choroid plexus",
          "benign tumor of the choroid plexus",
          "benign tumour of choroid plexus",
          "benign tumour of the choroid plexus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0044764"
    },
    {
      "id": 26051,
      "label": "benign vascular tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:235124",
          "Orphanet:673470",
          "UMLS:C1377916"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 6,
      "reference_id": "MONDO:0971115"
    },
    {
      "id": 26052,
      "label": "borderline vascular tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:232657",
          "Orphanet:673473",
          "UMLS:C1334225"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 1,
      "reference_id": "MONDO:0971116"
    },
    {
      "id": 26095,
      "label": "littoral cell hemangioma of the spleen",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        21330
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027214",
          "Orphanet:673538"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0975752"
    }
  ],
  "roots": [
    {
      "id": 21585,
      "label": "cardiovascular neoplasm"
    }
  ]
}