{
  "id": 21333,
  "label": "hypophosphatemic rickets",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024300",
  "properties": {
    "xrefs": [
      "GARD:0025385",
      "MEDGEN:309957",
      "MESH:D063730",
      "NANDO:1200778",
      "NANDO:1200780",
      "NANDO:2200402",
      "NANDO:2200403",
      "NCIT:C131449",
      "UMLS:C1704375"
    ],
    "synonyms": [
      "Phosphopenic rickets",
      "hypophosphatemic rickets",
      "acquired vitamin D resistant rickets",
      "acquired vitamin D-resistant rickets",
      "Ricket, hypophosphatemic",
      "hypophosphatemia, vitamin D-resistant rickets",
      "hypophosphatemic Ricket",
      "hypophosphatemic vitamin D resistant rickets",
      "hypophosphatemic vitamin D-resistant rickets",
      "rickets, vitamin D resistant",
      "rickets, vitamin D-resistant",
      "vitamin D-resistant rickets"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Rickets due to low serum phosphate concentrations, the cause of which can be nutritional or genetic. This condition is characterized by normal parathyroid hormone concentrations, usually caused by renal phosphate wasting occurring in isolation or as part of a renal tubular disorder, and characterized by resistance to treatment with ultraviolet radiation or vitamin D."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 7175,
      "label": "rickets",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3151
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10609",
          "EFO:0005583",
          "GARD:0005700",
          "HP:0002748",
          "ICD9:268.0",
          "MEDGEN:48470",
          "MESH:D012279",
          "NCIT:C26878",
          "SCTID:41345002",
          "UMLS:C0035579"
        ],
        "synonyms": [
          "rachitis",
          "rickets",
          "rickets (disease)",
          "vitamin D hydroxylation-deficient rickets",
          "active rickets",
          "hypovitaminosis D",
          "nutritional rickets",
          "vitamin D deficiency disease",
          "vitamin-D deficiency rickets"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Bone softening and weakening usually caused by deficiency or impaired metabolism of vitamin D. Deficiency of calcium, magnesium, or phosphorus may also cause rickets. It predominantly affects children who suffer from severe malnutrition. It manifests with bone pain, fractures, muscle weakness, and skeletal deformities."
      },
      "child_count": 4,
      "reference_id": "MONDO:0005520"
    }
  ],
  "children": [
    {
      "id": 2709,
      "label": "hereditary hypophosphatemic rickets",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        21333
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0006735",
          "MedDRA:10060873",
          "OMIMPS:193100",
          "Orphanet:437",
          "icd11.foundation:1010293846"
        ],
        "synonyms": [
          "hereditary hypophosphatemic rickets"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Hypophosphatemic rickets is a group of genetic diseases characterized by hypophosphatemia, rickets, and normal serum levels of calcium."
      },
      "child_count": 8,
      "reference_id": "MONDO:0000044"
    }
  ],
  "roots": [
    {
      "id": 7175,
      "label": "rickets"
    }
  ]
}