{
  "id": 21351,
  "label": "viral infection of central nervous system",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024318",
  "properties": {
    "xrefs": [
      "GARD:0025391",
      "ICD10CM:A80-A89",
      "ICD10WHO:A80-A89",
      "MEDGEN:91141",
      "MESH:D020805",
      "SCTID:302810003",
      "UMLS:C0348165"
    ],
    "synonyms": [
      "viral infection of central nervous system",
      "central nervous system viral infection",
      "viral disease of central nervous system"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 6834,
      "label": "viral infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:934",
          "EFO:0000763",
          "ICD9:060-066",
          "ICD9:066.9",
          "ICD9:078.89",
          "ICD9:079.99",
          "MESH:D014777",
          "NCIT:C3439",
          "SCTID:34014006"
        ],
        "synonyms": [
          "Viruses caused disease or disorder",
          "Viruses disease or disorder",
          "Viruses infection",
          "Viruses infectious disease",
          "infection, viral",
          "viral disease",
          "viral disorder",
          "viral infection",
          "infections, Viruses"
        ],
        "definition": "Any disease caused by a virus."
      },
      "child_count": 42,
      "reference_id": "MONDO:0005108"
    },
    {
      "id": 21534,
      "label": "central nervous system infectious disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657,
        19708
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001456",
          "GARD:0025438",
          "ICD9:349.89",
          "MEDGEN:1684837",
          "MESH:D002494",
          "NCIT:C27582",
          "SCTID:128117002",
          "UMLS:C4759823"
        ],
        "synonyms": [
          "central nervous system infectious disease",
          "central nervous system infectious disorder",
          "infectious disease of central nervous system",
          "central nervous system infection",
          "infections, central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An infectious process that affects the brain and/or spinal cord. Representative examples include encephalitis, poliomyelitis, arachnoiditis, and meningitis."
      },
      "child_count": 24,
      "reference_id": "MONDO:0024619"
    }
  ],
  "children": [
    {
      "id": 3665,
      "label": "lymphocytic choriomeningitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7286,
        8436,
        21351,
        23869
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12155",
          "GARD:0022945",
          "ICD10CM:A87.2",
          "ICD9:049.0",
          "MEDGEN:44220",
          "MESH:D008216",
          "UMLS:C0024266",
          "icd11.foundation:307264938"
        ],
        "synonyms": [
          "lymphocytic meningitis",
          "lymphocytic choriomeningitis mammarenavirus caused infectious meningitis",
          "lymphocytic choriomeningitis mammarenavirus infectious meningitis",
          "lymphocytic meningoencephalitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A form of meningitis caused by lymphocytic choriomeningitis virus. mice and other rodents serve as the natural hosts, and infection in humans usually occurs through inhalation or ingestion of infectious particles. Clinical manifestations include an influenza-like syndrome followed by stiff neck, alterations of mentation, ataxia, and incontinence. Maternal infections may result in fetal malformations and injury, including neonatal hydrocephalus, aqueductal stenosis, chorioretinitis, and microcephaly. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0001449"
    },
    {
      "id": 7326,
      "label": "central nervous system AIDS arteritis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5281,
        6835,
        21351
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024219",
          "MEDGEN:156263",
          "MESH:D020943",
          "UMLS:C0752330"
        ],
        "synonyms": [
          "AIDS associated cerebral aneurysmal arteriopathy",
          "AIDS-associated cerebral aneurysmal arteriopathy",
          "CNS Vasculitides, HIV-1-associated",
          "CNS Vasculitides, HIV-associated",
          "CNS vasculitis, HIV associated",
          "CNS vasculitis, HIV-1-associated",
          "CNS vasculitis, HIV-associated",
          "HIV 1 associated CNS vasculitis",
          "HIV associated vasculitis of the central nervous system",
          "HIV-1-associated CNS Vasculitides",
          "HIV-1-associated CNS vasculitis",
          "HIV-associated CNS Vasculitides",
          "HIV-associated CNS vasculitis",
          "HIV-associated vasculitis of the central nervous system",
          "Vasculitides, HIV-1-associated CNS",
          "Vasculitides, HIV-associated CNS",
          "central nervous system AIDS arteritis",
          "cerebral aneurysmal arteriopathy, AIDS associated",
          "cerebral aneurysmal arteriopathy, AIDS-associated",
          "vasculitis of the central nervous system, HIV associated",
          "vasculitis of the central nervous system, HIV-associated",
          "vasculitis, HIV-1-associated CNS",
          "vasculitis, HIV-associated CNS"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Inflammation of arteries in the central nervous system that occurs in patients with acquired immunodeficiency syndrome or aids-related opportunistic infections."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005695"
    },
    {
      "id": 7389,
      "label": "geniculate herpes zoster",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7250,
        7300,
        20716,
        21351
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9210",
          "EFO:0007281",
          "GARD:0007525",
          "ICD9:053.11",
          "ICD9:351.8",
          "MEDGEN:6581",
          "NCIT:C84763",
          "NORD:1647",
          "Orphanet:3020",
          "SCTID:95670000",
          "UMLS:C0017409"
        ],
        "synonyms": [
          "Herpes Zoster Oticus",
          "Ramsay Hunt Syndrome",
          "Ramsay Hunt syndrome",
          "facial nerve palsy due to VZV",
          "facial nerve palsy due to herpes zoster infection",
          "facial nerve paralysis due to VZV",
          "Hunt syndrome (formerly)",
          "Hunt's syndrome (formerly)",
          "Ramsay Hunt syndrome type 2",
          "Ramsay Hunt syndrome type 2 (formerly)",
          "Ramsay Hunt syndrome type II"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A viral ear infection caused by the spread of varicella-zoster virus to the facial nerves. It is characterized by intense otalgia and a cutaneous vesicular eruption."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005769"
    },
    {
      "id": 7596,
      "label": "Venezuelan equine encephalitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6880,
        7280,
        18247,
        21351,
        23869
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9584",
          "EFO:0007534",
          "GARD:0006355",
          "ICD10CM:A92.2",
          "ICD9:066.2",
          "MEDGEN:4036",
          "MESH:D004685",
          "NCIT:C35121",
          "SCTID:417067005",
          "UMLS:C0014078",
          "icd11.foundation:608978790"
        ],
        "synonyms": [
          "Venezuelan equine encephalitis virus caused disease or disorder",
          "Venezuelan equine encephalitis virus disease or disorder",
          "Venezuelan equine encephalitis virus infectious disease",
          "Venezuelan equine fever"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A condition caused by infection by the Venezuelan equine encephalitis virus, which is characterized by headache, fever, myalgia, nausea, and vomiting."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006005"
    },
    {
      "id": 7600,
      "label": "viral encephalitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19721,
        21351,
        24062
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:646",
          "EFO:0007538",
          "GARD:0019433",
          "MEDGEN:116719",
          "MedDRA:10058805",
          "NCIT:C35302",
          "Orphanet:98252",
          "SCTID:34476008",
          "UMLS:C0243010"
        ],
        "synonyms": [
          "Viruses caused encephalitis",
          "Viruses encephalitis",
          "viral encephalitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Encephalitis resulting from viral infection."
      },
      "child_count": 36,
      "reference_id": "MONDO:0006009"
    },
    {
      "id": 17684,
      "label": "poliomyelitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4629,
        5143,
        19750,
        20092,
        21351,
        21533
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4953",
          "EFO:0007450",
          "GARD:0007413",
          "ICD9:045",
          "ICD9:045.9",
          "ICD9:045.90",
          "ICD9:045.92",
          "MEDGEN:18545",
          "MESH:D011051",
          "MedDRA:10036012",
          "NCIT:C35550",
          "Orphanet:2912",
          "SCTID:398102009",
          "UMLS:C0032371",
          "icd11.foundation:588527933"
        ],
        "synonyms": [
          "Polia",
          "acute poliomyelitis",
          "polio",
          "poliomyelitis",
          "infantile paralysis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An acute infectious disorder that affects the nervous system. It is caused by the poliovirus. The virus spreads by direct contact, and can be prevented by prophylaxis with the polio vaccine."
      },
      "child_count": 18,
      "reference_id": "MONDO:0017373"
    },
    {
      "id": 21535,
      "label": "meningitis caused by poliovirus",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6561,
        21351,
        21533
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025439",
          "MEDGEN:928803",
          "SCTID:721765009",
          "UMLS:C4303134"
        ],
        "synonyms": [
          "meningitis caused by human poliovirus",
          "polio virus meningitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0024620"
    }
  ],
  "roots": [
    {
      "id": 6834,
      "label": "viral infectious disease"
    },
    {
      "id": 21534,
      "label": "central nervous system infectious disorder"
    }
  ]
}