{
  "id": 21378,
  "label": "respiratory tract infectious disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024355",
  "properties": {
    "xrefs": [
      "ICD9:519.8",
      "MESH:D012141",
      "SCTID:275498002"
    ],
    "synonyms": [
      "respiratory infection, upper",
      "upper respiratory infections",
      "upper respiratory tract infections",
      "infection, respiratory tract",
      "infections, respiratory",
      "infections, respiratory tract",
      "infections, upper respiratory",
      "infections, upper respiratory tract",
      "respiratory infections",
      "respiratory tract infection"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 14,
  "parents": [
    {
      "id": 6815,
      "label": "respiratory system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1579",
          "EFO:0000684",
          "ICD10CM:J00-J99",
          "ICD9:460-519",
          "ICD9:500-508",
          "ICD9:503",
          "ICD9:508",
          "ICD9:508.1",
          "ICD9:508.8",
          "ICD9:508.9",
          "ICD9:510-519",
          "ICD9:516",
          "ICD9:516.8",
          "ICD9:516.9",
          "ICD9:517",
          "ICD9:517.8",
          "ICD9:519",
          "ICD9:519.1",
          "ICD9:519.3",
          "ICD9:519.8",
          "ICD9:519.9",
          "ICD9:V12.60",
          "ICD9:V47.2",
          "MEDGEN:48421",
          "MESH:D012140",
          "NANDO:1100010",
          "NCIT:C26871",
          "SCTID:50043002",
          "UMLS:C0035204"
        ],
        "synonyms": [
          "disease of respiratory system",
          "disease or disorder of respiratory system",
          "disorder of respiratory system",
          "respiratory disease",
          "respiratory disorder",
          "respiratory system disease",
          "respiratory system disease or disorder",
          "respiratory system disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma."
      },
      "child_count": 59,
      "reference_id": "MONDO:0005087"
    },
    {
      "id": 7200,
      "label": "infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050117",
          "EFO:0005741",
          "ICD10CM:A00-B99",
          "ICD9:079.0",
          "ICD9:136.8",
          "ICD9:136.9",
          "IDO:0000436",
          "MEDGEN:1057",
          "MESH:D003141",
          "NCIT:C26726",
          "SCTID:40733004",
          "UMLS:C0009450"
        ],
        "synonyms": [
          "communicable disease",
          "infection",
          "infectious",
          "infectious disease",
          "infectious diseases and manifestations",
          "infectious disorder",
          "transmissible disease",
          "clinical infection",
          "disease by infectious agent"
        ],
        "definition": "A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact."
      },
      "child_count": 35,
      "reference_id": "MONDO:0005550"
    }
  ],
  "children": [
    {
      "id": 3117,
      "label": "lung abscess",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6939,
        6971,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060317",
          "EFO:1001362",
          "HP:0025044",
          "ICD9:513.0",
          "MEDGEN:7397",
          "MESH:D008169",
          "NCIT:C99090",
          "SCTID:73452002",
          "UMLS:C0024110"
        ],
        "synonyms": [
          "lung abscess",
          "lung abscess (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A bacterial, fungal or parasitic abscess that develops in the lung parenchyma. Causes include aspiration pneumonia, necrotizing pneumonia, necrotizing malignant tumors, and Wegener's granulomatosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000744"
    },
    {
      "id": 3283,
      "label": "pneumonic plague",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971,
        18984,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10398",
          "GARD:0022865",
          "ICD10CM:A20.2",
          "ICD9:020.3",
          "ICD9:020.4",
          "ICD9:020.5",
          "MEDGEN:105580",
          "SCTID:35339003",
          "UMLS:C0524688",
          "icd11.foundation:1983098110"
        ],
        "synonyms": [
          "primary pneumonic plague",
          "secondary pneumonic plague"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A plague in which the bacteria have infected the lungs."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001024"
    },
    {
      "id": 6953,
      "label": "pneumonia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21378,
        23261
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:552",
          "EFO:0003106",
          "ICD10CM:J15",
          "ICD10CM:J18.9",
          "ICD9:483",
          "ICD9:483.8",
          "ICD9:484.8",
          "ICD9:486",
          "MEDGEN:10813",
          "MESH:D011014",
          "NCIT:C3333",
          "SCTID:233604007",
          "UMLS:C0032285",
          "icd11.foundation:142052508"
        ],
        "synonyms": [
          "acute pneumonia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005249"
    },
    {
      "id": 7386,
      "label": "fungal lung infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4188,
        6971,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007278",
          "MEDGEN:6144",
          "MESH:D008172",
          "UMLS:C0024116"
        ],
        "synonyms": [
          "Fungi caused lung disease",
          "Fungi lung disease",
          "fungal disease, pulmonary",
          "fungal diseases, pulmonary",
          "fungal infection, pulmonary",
          "fungal infections, pulmonary",
          "fungal lung disease",
          "fungal lung diseases",
          "lung disease, fungal",
          "pulmonary fungal disease",
          "pulmonary fungal diseases",
          "pulmonary fungal infection",
          "pulmonary fungal infections"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Pulmonary diseases caused by fungal infections, usually through hematogenous spread."
      },
      "child_count": 15,
      "reference_id": "MONDO:0005766"
    },
    {
      "id": 7433,
      "label": "laryngeal tuberculosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2868,
        4698,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1583",
          "EFO:0007337",
          "GARD:0024235",
          "ICD9:012.3",
          "ICD9:012.30",
          "ICD9:012.31",
          "ICD9:012.32",
          "MEDGEN:11945",
          "MESH:D014387",
          "NCIT:C26895",
          "SCTID:70341005",
          "UMLS:C0041315"
        ],
        "synonyms": [
          "larynx tuberculosis",
          "tuberculous laryngitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Extrapulmonary tuberculosis involving the larynx. Signs and symptoms include hoarseness, cough, and odynophagia. The condition is rare."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005819"
    },
    {
      "id": 7524,
      "label": "pleural tuberculosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2868,
        3253,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:106",
          "EFO:0007446",
          "GARD:0024256",
          "ICD10CM:A15.6",
          "ICD9:010.1",
          "ICD9:010.10",
          "ICD9:010.12",
          "ICD9:010.16",
          "ICD9:012.0",
          "ICD9:012.00",
          "MEDGEN:22517",
          "MESH:D014396",
          "NCIT:C26898",
          "SCTID:186172004",
          "UMLS:C0041326"
        ],
        "synonyms": [
          "pleura tuberculosis",
          "tuberculosis of pleura",
          "tuberculous pleurisy",
          "tuberculous pleuritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Inflammation of the pleura secondary to an infection with Mycobacterium tuberculosis."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005922"
    },
    {
      "id": 7582,
      "label": "tracheitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4630,
        6839,
        20016,
        20781,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9392",
          "EFO:0007518",
          "ICD10CM:J04.1",
          "ICD9:464.1",
          "MEDGEN:11870",
          "MESH:D014136",
          "NCIT:C78643",
          "SCTID:62994001",
          "UMLS:C0040584"
        ],
        "synonyms": [
          "acute tracheitis",
          "inflammation of tracheal mucosa",
          "tracheal Inflammation",
          "tracheal mucosa inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A tracheal disease which involves bacterial infection of the trachea often caused by Staphylococcus aureus and streptococci that follows a recent viral upper respiratory infection. The symptoms include barking croup cough, loud squeaking noise while breathing, scratchy feeling in the throat, high fever, and production of large amounts of pus-filled secretions."
      },
      "child_count": 5,
      "reference_id": "MONDO:0005990"
    },
    {
      "id": 18509,
      "label": "pulmonary non-tuberculous mycobacterial infection",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6971,
        20027,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0012829",
          "MEDGEN:758704",
          "NORD:1887",
          "Orphanet:411703",
          "UMLS:C3472679",
          "icd11.foundation:1798822437"
        ],
        "synonyms": [
          "Nontuberculous Mycobacterial Lung Disease",
          "non-tuberculous mycobacterial lung disease",
          "nontuberculous mycobacterial lung disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018469"
    },
    {
      "id": 20241,
      "label": "laryngeal diphtheria",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6195,
        7160,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025266",
          "ICD10CM:A36.2",
          "ICD9:032.3",
          "MEDGEN:4336",
          "NCIT:C34546",
          "SCTID:50215002",
          "UMLS:C0012557",
          "icd11.foundation:1101542926"
        ],
        "synonyms": [
          "laryngeal diphtheria",
          "Diphtheritic laryngotracheitis",
          "Laryngeal Diphtheria",
          "Laryngeal diphtheria",
          "diphtheritic laryngotracheitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Infection of the larynx by Corynebacterium diphtheriae."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020863"
    },
    {
      "id": 20242,
      "label": "nasopharyngeal diphtheria",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6581,
        7160,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025267",
          "ICD10CM:A36.1",
          "ICD9:032.1",
          "MEDGEN:4337",
          "NCIT:C34547",
          "SCTID:75589004",
          "UMLS:C0012558"
        ],
        "synonyms": [
          "nasopharyngeal diphtheria",
          "Nasopharyngeal Diphtheria",
          "Nasopharyngeal diphtheria"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "Infection of the nasopharynx by Corynebacterium diphtheriae."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020866"
    },
    {
      "id": 20752,
      "label": "streptococcal sore throat",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4374,
        20725,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:J02.0",
          "ICD9:034.0",
          "MEDGEN:508129",
          "NCIT:C116003",
          "SCTID:43878008",
          "UMLS:C0036689"
        ],
        "synonyms": [
          "strep throat",
          "streptococcal pharyngitis",
          "Septic sore throat",
          "Strep throat",
          "Strept throat",
          "Streptococcal Pharyngitis",
          "Streptococcal angina",
          "Streptococcal pharyngitis",
          "Streptococcal sore throat"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Inflammation of the throat due to Streptococcus pyogenes."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021783"
    },
    {
      "id": 20753,
      "label": "silicotuberculosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7552,
        7636,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025351",
          "ICD9:502",
          "MEDGEN:11426",
          "MESH:D012830",
          "SCTID:233763009",
          "UMLS:C0037118"
        ],
        "synonyms": [
          "silicotuberculoses",
          "silicotuberculosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Tuberculosis caused by the infection of Mycobacterium tuberculosis in patients with silicosis (that is caused by inhalation of silica dust particles). The risk of a patient with silicosis developing pulmonary tuberculosis and extra-pulmonary tuberculosis is higher than in healthy population."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021804"
    },
    {
      "id": 20792,
      "label": "tuberculous fibrosis of lung",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4804,
        7636,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025358",
          "ICD9:011.40",
          "ICD9:011.41",
          "ICD9:011.42",
          "ICD9:011.43",
          "ICD9:011.44",
          "ICD9:011.46",
          "MEDGEN:21729",
          "NCIT:C35088",
          "SCTID:90117007",
          "UMLS:C0041336"
        ],
        "synonyms": [
          "tuberculous fibrosis of lung",
          "Tuberculous Fibrosis of Lung",
          "Tuberculous fibrosis of lung"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Scarring of the lung parenchyma caused by pulmonary tuberculosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021953"
    },
    {
      "id": 21376,
      "label": "viral respiratory tract infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6834,
        21378
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:519.8",
          "MEDGEN:163755",
          "NCIT:C27219",
          "SCTID:312133006",
          "UMLS:C0877203"
        ],
        "synonyms": [
          "viral respiratory tract infection"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A respiratory tract infection caused by a virus. Viruses represent the most common causes of upper and lower respiratory tract infections and include rhinoviruses, influenza viruses, parainfluenza viruses, and respiratory syncytial virus."
      },
      "child_count": 12,
      "reference_id": "MONDO:0024352"
    }
  ],
  "roots": [
    {
      "id": 6815,
      "label": "respiratory system disorder"
    },
    {
      "id": 7200,
      "label": "infectious disease"
    }
  ]
}