{
  "id": 21431,
  "label": "epithelial neoplasm of rectum",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024476",
  "properties": {
    "synonyms": [
      "rectal epithelial neoplasm",
      "rectal epithelial tumor",
      "rectal epithelial tumour",
      "rectum epithelial neoplasm"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A epithelial neoplasm that involves the rectum."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4291,
      "label": "rectal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3792,
        7022
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1984",
          "MEDGEN:11148",
          "MESH:D012004",
          "NCIT:C3350",
          "SCTID:126847008",
          "UMLS:C0034885"
        ],
        "synonyms": [
          "neoplasm of rectum",
          "neoplasm of the rectum",
          "rectal neoplasm",
          "rectal tumor",
          "rectal tumour",
          "rectum neoplasm (disease)",
          "rectum tumor",
          "rectum tumour",
          "tumor of rectum",
          "tumor of the rectum",
          "tumour of rectum",
          "tumour of the rectum"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the rectum. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Rectal adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002165"
    },
    {
      "id": 7265,
      "label": "epithelial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0006858",
          "MEDGEN:277963",
          "MESH:D009375",
          "NCIT:C3709",
          "SCTID:118285006",
          "UMLS:C1368683"
        ],
        "synonyms": [
          "epithelial neoplasm",
          "epithelioma"
        ],
        "definition": "A benign or malignant neoplasm that arises from and is composed of epithelial cells. This category include adenomas, papillomas, and carcinomas."
      },
      "child_count": 24,
      "reference_id": "MONDO:0005626"
    }
  ],
  "children": [
    {
      "id": 2976,
      "label": "rectum adenoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7140,
        21431
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050915",
          "MEDGEN:266267",
          "NCIT:C5546",
          "SCTID:399730005",
          "UMLS:C1302652"
        ],
        "synonyms": [
          "adenoma of rectum",
          "adenoma of the rectum",
          "rectal adenoma",
          "rectum adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An adenoma that arises from the rectum. The group of rectal adenomas includes tubular, villous, and tubulovillous adenomas, traditional serrated adenomas, sessile serrated adenomas/polyps, and familial adenomatous polyposis."
      },
      "child_count": 8,
      "reference_id": "MONDO:0000530"
    },
    {
      "id": 5534,
      "label": "rectum neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4896,
        21431
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5777",
          "GARD:0019756",
          "MEDGEN:277576",
          "NCIT:C5698",
          "UMLS:C1335686",
          "icd11.foundation:1619951900"
        ],
        "synonyms": [
          "neuroendocrine neoplasm of rectum",
          "neuroendocrine neoplasm of the rectum",
          "rectal neuroendocrine neoplasm",
          "rectum neuroendocrine neoplasm",
          "NET of the rectum",
          "neuroendocrine tumor of rectum",
          "neuroendocrine tumour of rectum",
          "rectal NET",
          "rectal neuroendocrine tumor",
          "rectum NET",
          "rectum neuroendocrine tumor",
          "rectum neuroendocrine tumor, well differentiated, low or intermediate grade",
          "rectum neuroendocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation that arises from the rectum. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003646"
    },
    {
      "id": 23485,
      "label": "rectal carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8006,
        21360,
        21431
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:40100",
          "NCIT:C9382",
          "UMLS:C0007113"
        ],
        "synonyms": [
          "cancer of rectum",
          "cancer of the rectum",
          "rectal cancer",
          "carcinoma of rectum",
          "carcinoma of the rectum",
          "rectal carcinoma",
          "rectum carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant epithelial neoplasm that arises from the rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas."
      },
      "child_count": 18,
      "reference_id": "MONDO:0044937"
    }
  ],
  "roots": [
    {
      "id": 4291,
      "label": "rectal neoplasm"
    },
    {
      "id": 7265,
      "label": "epithelial neoplasm"
    }
  ]
}