{
  "id": 21452,
  "label": "vascular bone neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024499",
  "properties": {
    "xrefs": [
      "GARD:0025402",
      "MEDGEN:234986",
      "NCIT:C6478",
      "UMLS:C1336946"
    ],
    "synonyms": [
      "bone vascular neoplasm",
      "bone vascular tumor",
      "bone vascular tumour",
      "osseous vascular neoplasm",
      "osseous vascular tumor",
      "osseous vascular tumour",
      "vascular bone neoplasm",
      "vascular neoplasm of bone",
      "vascular neoplasm of the bone",
      "vascular tumor of bone",
      "vascular tumor of the bone",
      "vascular tumour of bone",
      "vascular tumour of the bone"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A benign, intermediate, or malignant vascular neoplasm that arises from the bone."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 18958,
      "label": "bone neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7061,
        20678
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003820",
          "GARD:0018892",
          "ICD10CM:C40-C41",
          "MEDGEN:488993",
          "NCIT:C9343",
          "ONCOTREE:BONE",
          "Orphanet:68411",
          "UMLS:C2732838"
        ],
        "synonyms": [
          "bone neoplasm",
          "bone neoplasms",
          "bone tissue neoplasm",
          "bone tissue tumor",
          "bone tissue tumour",
          "bone tumor",
          "bone tumors",
          "bone tumour",
          "bone tumours",
          "neoplasm of bone",
          "neoplasm of bone tissue",
          "neoplasm of the bone",
          "osseous neoplasm",
          "osseous tumor",
          "osseous tumour",
          "tumor of bone",
          "tumor of bone tissue",
          "tumor of the bone",
          "tumour of bone",
          "tumour of bone tissue",
          "tumour of the bone",
          "primary bone cancer",
          "primary malignant neoplasm of bone",
          "rare bone tumor",
          "rare bone tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage."
      },
      "child_count": 40,
      "reference_id": "MONDO:0019060"
    },
    {
      "id": 21330,
      "label": "vascular neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21585
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:129202",
          "NCIT:C7388",
          "UMLS:C0282607"
        ],
        "synonyms": [
          "neoplasm of vascular system",
          "neoplasm of vascular tissue",
          "neoplasms, vascular",
          "tumor of vascular system",
          "tumor of vascular tissue",
          "tumors, vascular",
          "tumour of vascular system",
          "tumour of vascular tissue",
          "vascular neoplasm",
          "vascular neoplasms",
          "vascular system neoplasm",
          "vascular system neoplasm (disease)",
          "vascular system tumor",
          "vascular system tumour",
          "vascular tissue neoplasm",
          "vascular tissue tumor",
          "vascular tissue tumour",
          "vascular tumor",
          "vascular tumors",
          "vascular tumour",
          "vascular tumours"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A benign, intermediate, or malignant neoplasm arising from vascular tissue including arteries, veins, venous sinuses, lymphatic vessels, arterioles and capillaries. It may occur in essentially any body location and is characterized by the presence of vascular channel formation and endothelial cells."
      },
      "child_count": 16,
      "reference_id": "MONDO:0024296"
    }
  ],
  "children": [
    {
      "id": 4668,
      "label": "bone angiosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17394,
        20297,
        21452
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3351",
          "GARD:0023189",
          "MEDGEN:231448",
          "NCIT:C6479",
          "UMLS:C1332574"
        ],
        "synonyms": [
          "angiosarcoma (disease) of bone tissue",
          "bone Hemangioendothelial sarcoma",
          "bone angioendothelial sarcoma",
          "bone angiosarcoma",
          "bone hemangiosarcoma",
          "bone tissue angiosarcoma (disease)",
          "osseous angioendothelial sarcoma",
          "osseous angiosarcoma",
          "osseous hemangiosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A high-grade malignant vascular neoplasm that arises from the bone. It is characterized by the presence of neoplastic cells with endothelial differentiation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002617"
    },
    {
      "id": 4995,
      "label": "cavernous sinus meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4997,
        6420,
        20321,
        21452,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4435",
          "GARD:0023317",
          "MEDGEN:232034",
          "NCIT:C5268",
          "UMLS:C1332865"
        ],
        "synonyms": [
          "cavernous sinus meningioma (disease)",
          "meningioma (disease) of cavernous sinus",
          "meningioma of cavernous sinus",
          "meningioma of the cavernous sinus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the cavernous sinus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002996"
    },
    {
      "id": 7833,
      "label": "malignant jugulotympanic paraganglioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4233,
        4265,
        4753,
        6420,
        20305,
        20310,
        20329,
        21452,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024363",
          "MEDGEN:87584",
          "NCIT:C4623",
          "UMLS:C0347856"
        ],
        "synonyms": [
          "cancer of jugular body",
          "jugular body cancer",
          "malignant glomus jugulare neoplasm",
          "malignant glomus jugulare tumor",
          "malignant glomus jugulare tumour",
          "malignant jugular body neoplasm",
          "malignant jugulotympanic paraganglioma",
          "malignant neoplasm of glomus jugulare",
          "malignant neoplasm of jugular body",
          "malignant neoplasm of the glomus jugulare",
          "malignant tumor of glomus jugulare",
          "malignant tumor of the glomus jugulare",
          "malignant tumour of glomus jugulare",
          "malignant tumour of the glomus jugulare"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A jugulotympanic paraganglioma that metastasizes to other anatomic sites."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006291"
    },
    {
      "id": 14824,
      "label": "Maffucci syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4599,
        16218,
        19142,
        19480,
        19507,
        21247,
        21452,
        23867
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060221",
          "GARD:0006958",
          "MEDGEN:7437",
          "NCIT:C3213",
          "NORD:1393",
          "OMIM:614569",
          "Orphanet:163634",
          "SCTID:46041001",
          "UMLS:C0024454",
          "icd11.foundation:548780091"
        ],
        "synonyms": [
          "Chondroplasia angiomatosis",
          "Dyschondroplasia and cavernous hemangioma",
          "Maffucci syndrome",
          "Maffucci type enchondromatosis",
          "Maffucci's anomalad",
          "chondrodysplasia with hemangioma",
          "enchondromatosis with hemangiomata",
          "hemangiomata with Dyschondroplasia",
          "Dyschondrodysplasia with hemangiomas",
          "Kast syndrome",
          "enchondromatosis with multiple cavernous hemangiomas",
          "hemangiomatosis Chondrodystrophica",
          "multiple Angiomas and Endochondromas",
          "multiple enchondromatosis, Maffucci type"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Maffucci syndrome is a very rare genetic bone and skin disorder characterized by multiple enchondromas, leading to bone deformities, combined with multiple dark, irregularly shaped hemangiomas or less commonly lymphangiomas."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013808"
    }
  ],
  "roots": [
    {
      "id": 18958,
      "label": "bone neoplasm"
    },
    {
      "id": 21330,
      "label": "vascular neoplasm"
    }
  ]
}