{
  "id": 21454,
  "label": "appendix neuroendocrine neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024501",
  "properties": {
    "xrefs": [
      "GARD:0025404",
      "MEDGEN:361887",
      "NCIT:C60709",
      "UMLS:C1879718"
    ],
    "synonyms": [
      "appendix neuroendocrine neoplasm",
      "neuroendocrine neoplasm of vermiform appendix",
      "vermiform appendix NET",
      "vermiform appendix neuroendocrine neoplasm",
      "vermiform appendix neuroendocrine tumor",
      "vermiform appendix neuroendocrine tumor, well differentiated, low or intermediate grade",
      "vermiform appendix neuroendocrine tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A neoplasm with neuroendocrine differentiation that arises from the appendix. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 3476,
      "label": "appendiceal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7325,
        23661
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11240",
          "EFO:0003880",
          "GARD:0027340",
          "MEDGEN:1629",
          "MESH:D001063",
          "NCIT:C4434",
          "SCTID:126846004",
          "UMLS:C0003614"
        ],
        "synonyms": [
          "appendix neoplasm",
          "appendix tumor",
          "appendix tumour",
          "neoplasm of appendix",
          "neoplasm of the appendix",
          "neoplasm of vermiform appendix",
          "tumor of appendix",
          "tumor of the appendix",
          "tumor of vermiform appendix",
          "tumour of appendix",
          "tumour of the appendix",
          "tumour of vermiform appendix",
          "vermiform appendix neoplasm",
          "vermiform appendix neoplasm (disease)",
          "vermiform appendix tumor",
          "vermiform appendix tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm involving the appendix."
      },
      "child_count": 8,
      "reference_id": "MONDO:0001236"
    },
    {
      "id": 4895,
      "label": "colon neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4896,
        7078
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4118",
          "GARD:0019755",
          "MEDGEN:234162",
          "NCIT:C5697",
          "Orphanet:100080",
          "UMLS:C1333097",
          "icd11.foundation:144503516"
        ],
        "synonyms": [
          "colon NET",
          "colon neuroendocrine neoplasm",
          "colon neuroendocrine tumor",
          "colon neuroendocrine tumor, well differentiated, low or intermediate grade",
          "colon neuroendocrine tumour",
          "colonic neuroendocrine neoplasm",
          "colonic neuroendocrine tumour",
          "neuroendocrine neoplasm of colon",
          "neuroendocrine neoplasm of the colon",
          "neuroendocrine tumor of the colon",
          "neuroendocrine tumour of the colon"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation that arises from the colon. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002882"
    }
  ],
  "children": [
    {
      "id": 16040,
      "label": "neuroendocrine tumor of the appendix, well differentiated, low or intermediate grade",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16041,
        18543,
        21454
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019754",
          "MEDGEN:474400",
          "NCIT:C96422",
          "ONCOTREE:AWDNET",
          "Orphanet:100079",
          "SCTID:725167001",
          "UMLS:C3272767",
          "icd11.foundation:1590340268"
        ],
        "synonyms": [
          "NEN of appendix",
          "appendiceal NEN",
          "appendiceal neuroendocrine neoplasm",
          "appendiceal neuroendocrine tumor",
          "appendiceal neuroendocrine tumour",
          "appendix NET",
          "appendix neuroendocrine tumor",
          "appendix neuroendocrine tumour",
          "appendix well differentiated endocrine tumor",
          "appendix well differentiated endocrine tumor/carcinoma",
          "appendix well differentiated endocrine tumour",
          "neuroendocrine neoplasm of appendix",
          "well-differentiated neuroendocrine tumor of the appendix",
          "well-differentiated neuroendocrine tumour of the appendix"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A well differentiated, low or intermediate grade tumor with neuroendocrine differentiation that arises from the appendix."
      },
      "child_count": 12,
      "reference_id": "MONDO:0015066"
    }
  ],
  "roots": [
    {
      "id": 3476,
      "label": "appendiceal neoplasm"
    },
    {
      "id": 4895,
      "label": "colon neuroendocrine neoplasm"
    }
  ]
}