{
  "id": 21455,
  "label": "gallbladder neuroendocrine neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024502",
  "properties": {
    "xrefs": [
      "GARD:0025405",
      "MEDGEN:474748",
      "NCIT:C96917",
      "UMLS:C3273115"
    ],
    "synonyms": [
      "gall bladder NET",
      "gall bladder neuroendocrine neoplasm",
      "gall bladder neuroendocrine tumor",
      "gall bladder neuroendocrine tumor, well differentiated, low or intermediate grade",
      "gall bladder neuroendocrine tumour",
      "gallbladder neuroendocrine neoplasm",
      "neuroendocrine neoplasm of gall bladder"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A neoplasm with neuroendocrine differentiation that arises from the gallbladder. It includes well differentiated neuroendocrine tumors (low and intermediate grade) and poorly differentiated neuroendocrine carcinomas (high grade)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 20460,
      "label": "gallbladder neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4585,
        6977
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0004606",
          "MEDGEN:42134",
          "MESH:D005706",
          "NCIT:C3048",
          "UMLS:C0016978"
        ],
        "synonyms": [
          "gall bladder neoplasm",
          "gall bladder neoplasm (disease)",
          "gall bladder tumor",
          "gall bladder tumour",
          "gallbladder tumor",
          "gallbladder tumour",
          "neoplasm of gall bladder",
          "neoplasm of gallbladder",
          "neoplasm of the gallbladder",
          "tumor of gall bladder",
          "tumor of gallbladder",
          "tumor of the gallbladder",
          "tumour of gall bladder",
          "tumour of gallbladder",
          "tumour of the gallbladder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the gall bladder."
      },
      "child_count": 12,
      "reference_id": "MONDO:0021253"
    },
    {
      "id": 21456,
      "label": "digestive system neuroendocrine neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6151,
        19314,
        20434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0002437",
          "MEDGEN:232237",
          "MESH:C535650",
          "NCIT:C27721",
          "Orphanet:100092",
          "UMLS:C1333799"
        ],
        "synonyms": [
          "alimentary part of gastrointestinal system NET",
          "alimentary part of gastrointestinal system neuroendocrine neoplasm",
          "alimentary part of gastrointestinal system neuroendocrine tumor",
          "alimentary part of gastrointestinal system neuroendocrine tumor, well differentiated, low or intermediate grade",
          "alimentary part of gastrointestinal system neuroendocrine tumour",
          "carcinoid tumor of digestive system",
          "carcinoid tumour of digestive system",
          "digestive system NET",
          "digestive system neuroendocrine neoplasm",
          "digestive system neuroendocrine tumor",
          "digestive system neuroendocrine tumor, well differentiated, low or intermediate grade",
          "digestive system neuroendocrine tumour",
          "gastro-enteropancreatic neuroendocrine tumor",
          "gastro-enteropancreatic neuroendocrine tumour",
          "gastroenteropancreatic endocrine tumor",
          "gastroenteropancreatic endocrine tumour",
          "gastroenteropancreatic neuroendocrine neoplasm",
          "gastrointestinal neuroendocrine neoplasm",
          "gastrointestinal system neuroendocrine neoplasm",
          "neuroendocrine neoplasm of alimentary part of gastrointestinal system",
          "neuroendocrine neoplasm of digestive system",
          "GEP tumors",
          "GEP tumours",
          "GEP-NEN",
          "GEP-NET",
          "carcinoid tumor",
          "carcinoid tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm with neuroendocrine differentiation arising from the digestive system. It includes neuroendocrine tumors (well-differentiated endocrine tumors or carcinoid tumors and well differentiated endocrine carcinomas) and neuroendocrine carcinomas (poorly differentiated neuroendocrine carcinomas, small cell carcinomas, and large cell neuroendocrine carcinomas)."
      },
      "child_count": 21,
      "reference_id": "MONDO:0024503"
    }
  ],
  "children": [
    {
      "id": 7772,
      "label": "gallbladder small cell neuroendocrine carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        5174,
        21455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7133",
          "EFO:1000266",
          "GARD:0024335",
          "MEDGEN:232229",
          "NCIT:C6763",
          "UMLS:C1333759"
        ],
        "synonyms": [
          "Oat cell carcinoma of gallbladder",
          "Oat cell carcinoma of the gallbladder",
          "gall bladder small cell carcinoma",
          "gallbladder Oat cell carcinoma",
          "gallbladder small cell NEC",
          "gallbladder small cell carcinoma",
          "gallbladder small cell neuroendocrine carcinoma",
          "small cell carcinoma of gall bladder",
          "small cell carcinoma of gallbladder",
          "small cell carcinoma of the gallbladder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the gallbladder. It is characterized by the presence of malignant small cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006219"
    },
    {
      "id": 16047,
      "label": "gallbladder neuroendocrine tumor, grade 1/2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2885,
        20541,
        21455
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019761",
          "MEDGEN:474749",
          "NCIT:C96918",
          "Orphanet:100086",
          "UMLS:C3273116"
        ],
        "synonyms": [
          "gallbladder NET",
          "gallbladder neuroendocrine tumor",
          "gallbladder neuroendocrine tumour",
          "gallbladder well differentiated endocrine tumor",
          "gallbladder well differentiated endocrine tumor/carcinoma",
          "gallbladder well differentiated endocrine tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A well differentiated, low or intermediate grade tumor with neuroendocrine differentiation that arises from the gallbladder."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015073"
    }
  ],
  "roots": [
    {
      "id": 20460,
      "label": "gallbladder neoplasm"
    },
    {
      "id": 21456,
      "label": "digestive system neuroendocrine neoplasm"
    }
  ]
}