{
  "id": 21516,
  "label": "AIDS-related disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024571",
  "properties": {
    "xrefs": [
      "EFO:0009528",
      "MEDGEN:852920",
      "NCIT:C4991",
      "UMLS:C0877121"
    ],
    "synonyms": [
      "AIDS-related complications",
      "AIDS-related disorder",
      "AIDS/HIV - relatedDisease associated with AIDS",
      "disease associated with AIDS"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "A non-neoplastic or neoplastic disorder arising as a result of the immunologic defects caused by Autoimmune deficiency Syndrome."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 20721,
      "label": "post-viral disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20718
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:139.8",
          "MEDGEN:688821",
          "SCTID:123948009",
          "UMLS:C1264605"
        ],
        "synonyms": [
          "sequela of viral disease"
        ],
        "definition": "A post-infectious disorder that follows viral infection but is distinct from the viral infection itself and its usual manifestations."
      },
      "child_count": 13,
      "reference_id": "MONDO:0021674"
    },
    {
      "id": 21517,
      "label": "immunodeficiency-related disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6778
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:232641",
          "NCIT:C35686",
          "UMLS:C1334159"
        ],
        "synonyms": [
          "Immunodepression-related disorder",
          "Immunosuppression disorders",
          "Immunosuppression-related disorder",
          "immunodeficiency-related disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that develops in a patient with immunodeficiency. Representative examples include AIDS-related disorders and disorders that develop following organ transplantation."
      },
      "child_count": 1,
      "reference_id": "MONDO:0024572"
    }
  ],
  "children": [
    {
      "id": 7412,
      "label": "HIV enteropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        21516
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007311",
          "MEDGEN:79492",
          "MESH:D019053",
          "UMLS:C0282616"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A syndrome characterized by chronic, well-established diarrhea (greater than one month in duration) without an identified infectious cause after thorough evaluation, in an hiv-positive individual. It is thought to be due to direct or indirect effects of hiv on the enteric mucosa. hiv enteropathy is a diagnosis of exclusion and can be made only after other forms of diarrheal illness have been ruled out. (Harrison's Principles of Internal Medicine, 13th ed, pp1607-8; Haubrich et al., Bockus Gastroenterology, 5th ed, p1155)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0005796"
    },
    {
      "id": 7413,
      "label": "HIV wasting syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6835,
        21516
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007312",
          "GARD:0019122",
          "MEDGEN:87476",
          "MESH:D019247",
          "Orphanet:90081",
          "UMLS:C0343755"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Involuntary weight loss of greater than 10 percent associated with intermittent or constant fever and chronic diarrhea or fatigue for more than 30 days in the absence of a defined cause other than hiv infection. A constant feature is major muscle wasting with scattered myofiber degeneration. A variety of etiologies, which vary among patients, contributes to this syndrome. (From Harrison's Principles of Internal Medicine, 13th ed, p1611)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005797"
    },
    {
      "id": 7414,
      "label": "HIV-associated nephropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7046,
        21516
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007313",
          "GARD:0024232",
          "MEDGEN:37145",
          "MESH:D016263",
          "NCIT:C26918",
          "UMLS:C0078911"
        ],
        "synonyms": [
          "AIDS-associated nephropathy",
          "AIDS-related nephropathy",
          "HIV nephropathy",
          "HIVAN"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Renal disease in human immunodeficiency virus (HIV)-infected patients. It is characterized by nephrotic syndrome, azotemia, normal to large kidneys on ultrasound images, and focal segmental glomerulosclerosis on renal biopsy findings."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005798"
    },
    {
      "id": 18625,
      "label": "HIV-associated cancer",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17658,
        21516
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021857",
          "MEDGEN:1843219",
          "NCIT:C4046",
          "Orphanet:443291",
          "UMLS:C5680059"
        ],
        "synonyms": [
          "HIV-related cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018628"
    }
  ],
  "roots": [
    {
      "id": 20721,
      "label": "post-viral disorder"
    },
    {
      "id": 21517,
      "label": "immunodeficiency-related disorder"
    }
  ]
}