{
  "id": 21541,
  "label": "phagocytic cell dysfunction",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024627",
  "properties": {
    "xrefs": [
      "MEDGEN:585044",
      "SCTID:302874002",
      "UMLS:C0398732"
    ],
    "synonyms": [
      "defective phagocytosis",
      "phagocytic cell dysfunction"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 6778,
      "label": "immune system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2914",
          "EFO:0000540",
          "ICD9:279",
          "ICD9:279.1",
          "ICD9:279.10",
          "ICD9:279.19",
          "ICD9:279.4",
          "ICD9:279.49",
          "ICD9:279.8",
          "ICD9:279.9",
          "MEDGEN:5759",
          "MESH:D007154",
          "NANDO:1100004",
          "NANDO:2100202",
          "NCIT:C3507",
          "SCTID:414029004",
          "UMLS:C0021053"
        ],
        "synonyms": [
          "disease of immune system",
          "disease or disorder of immune system",
          "disorder of immune system",
          "immune disease",
          "immune disorder",
          "immune dysfunction",
          "immune system disease or disorder",
          "immune system disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A disorder resulting from an abnormality in the immune system."
      },
      "child_count": 47,
      "reference_id": "MONDO:0005046"
    }
  ],
  "children": [
    {
      "id": 7512,
      "label": "phagocyte bactericidal dysfunction",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5658,
        6569,
        21541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3262",
          "EFO:0007433",
          "GARD:0024253",
          "MEDGEN:14713",
          "MESH:D010585",
          "UMLS:C0031306"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Disorders in which phagocytic cells cannot kill ingested bacteria; characterized by frequent recurring infection with formulation of granulomas."
      },
      "child_count": 3,
      "reference_id": "MONDO:0005910"
    },
    {
      "id": 9539,
      "label": "phagocytosis, plasma-related defect 1N",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5714,
        21541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:356965",
          "MESH:C566808",
          "OMIM:171100",
          "UMLS:C1868402"
        ],
        "synonyms": [
          "phagocytosis, plasma-related defect type 1N",
          "phagocytosis, plasma-RELATED defect IN"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0008232"
    },
    {
      "id": 10579,
      "label": "familial lipochrome histiocytosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5714,
        21541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:90743",
          "MESH:C562738",
          "OMIM:235900",
          "SCTID:234577004",
          "UMLS:C0334125"
        ],
        "synonyms": [
          "histiocytosis, familial lipochrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0009347"
    },
    {
      "id": 18407,
      "label": "Langerhans cell histiocytosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4688,
        6569,
        19729,
        21541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2571",
          "EFO:1000318",
          "GARD:0006858",
          "ICD9:202.5",
          "ICD9:277.89",
          "ICDO:9751/1",
          "ICDO:9751/3",
          "ICDO:9752/1",
          "ICDO:9753/1",
          "ICDO:9754/3",
          "MEDGEN:5568",
          "MedDRA:10069698",
          "NANDO:2200031",
          "NCIT:C3107",
          "NORD:1348",
          "OMIM:604856",
          "ONCOTREE:LCH",
          "Orphanet:389",
          "SCTID:65399007",
          "UMLS:C0019621",
          "icd11.foundation:1388720498",
          "icd11.foundation:216625985"
        ],
        "synonyms": [
          "LCH",
          "Langerhans cell granulomatosis",
          "Langerhans cell histiocytosis",
          "Langerhans cell histiocytosis, NOS",
          "Langerhans cell histiocytosis, Not otherwise specified",
          "histiocytosis X",
          "Langerhans-cell histiocytosis",
          "Lch"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Langerhans cell histiocytosis (LCH) is a systemic disease associated with the proliferation and accumulation (usually in granulomas) of Langerhans cells in various tissues."
      },
      "child_count": 32,
      "reference_id": "MONDO:0018310"
    },
    {
      "id": 21540,
      "label": "defective phagocytic cell engulfment",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:585050",
          "SCTID:234585008",
          "UMLS:C0398742"
        ],
        "synonyms": [
          "defective phagocytic cell killing"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0024626"
    },
    {
      "id": 21542,
      "label": "defective phagocytic cell chemotaxis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        21541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:279.8",
          "MEDGEN:585047",
          "SCTID:234580003",
          "UMLS:C0398735"
        ],
        "synonyms": [
          "defective phagocytic cell chemotaxis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0024630"
    },
    {
      "id": 21543,
      "label": "defective phagocytic cell opsonization",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        21541
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:585045",
          "SCTID:234578009",
          "UMLS:C0398733"
        ],
        "synonyms": [
          "defective phagocytic cell opsonization"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0024632"
    }
  ],
  "roots": [
    {
      "id": 6778,
      "label": "immune system disorder"
    }
  ]
}