{
  "id": 21547,
  "label": "inflammation of heart layer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024636",
  "properties": {
    "xrefs": [
      "ICD9:429.89",
      "MEDGEN:163689",
      "SCTID:399617002",
      "UMLS:C0869523"
    ],
    "synonyms": [
      "carditis",
      "heart layer inflammation"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "An inflammatory disease involving a pathogenic inflammatory response in the heart layer."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6967,
      "label": "heart disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:114",
          "EFO:0003777",
          "ICD9:429.89",
          "ICD9:429.9",
          "ICD9:V47.2",
          "MEDGEN:5458",
          "MESH:D006331",
          "NCIT:C3079",
          "SCTID:56265001",
          "UMLS:C0018799",
          "icd11.foundation:1512587470"
        ],
        "synonyms": [
          "cardiac disease",
          "disease of heart",
          "disease or disorder of heart",
          "disorder of heart",
          "disorder of heart/pericardium",
          "heart disease",
          "heart disease or disorder",
          "heart disorder",
          "heart trouble",
          "heart/pericardial disease",
          "heart/pericardial disease or disorder",
          "heart/pericardial disorder",
          "heart/pericardial trouble"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease involving the heart and/or pericardium."
      },
      "child_count": 34,
      "reference_id": "MONDO:0005267"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 6298,
      "label": "myocarditis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3007,
        21547,
        21552
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:820",
          "EFO:0009609",
          "GARD:0007137",
          "ICD10CM:I40",
          "ICD9:429.0",
          "MEDGEN:44553",
          "MESH:D009205",
          "NCIT:C34831",
          "NORD:1882",
          "SCTID:50920009",
          "UMLS:C0027059",
          "icd11.foundation:1018829714"
        ],
        "synonyms": [
          "inflammation of myocardium",
          "myocardial inflammation (finding)",
          "myocardium inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Myocarditis is a condition that is characterized by inflammation of the heart muscle (myocardium). Some affected people have no noticeable symptoms of the condition. When present, signs and symptoms may include chest pain, abnormal heartbeat, shortness of breath, fatigue, signs of infection (i.e. fever, headache, sore throat, diarrhea), and leg swelling. Myocarditis can be caused by a variety of factors including infections (viral, bacterial, parasitic, and fungal), allergic reactions to certain medications, and exposure to certain chemicals. It can also be associated with other inflammatory conditions such as lupus, Wegener's granulomatosis, giant cell arteritis and Takayasu's arteritis. Most cases occur sporadically in people with no family history of the condition. Treatment aims to address the underlying cause of the condition. Medications and rarely, a heart transplant may be needed if the heart muscle becomes weak."
      },
      "child_count": 21,
      "reference_id": "MONDO:0004496"
    },
    {
      "id": 6759,
      "label": "endocarditis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2931,
        21547
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10314",
          "EFO:0000465",
          "HP:0100584",
          "ICD9:421.9",
          "ICD9:424.99",
          "MEDGEN:4940",
          "MESH:D004696",
          "NCIT:C34582",
          "SCTID:56819008",
          "UMLS:C0014118"
        ],
        "synonyms": [
          "endocarditis",
          "endocarditis (disease)",
          "endocardium inflammation",
          "inflammation of endocardium"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Inflammation of the endocardium."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005025"
    }
  ],
  "roots": [
    {
      "id": 6967,
      "label": "heart disorder"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}