{
  "id": 21549,
  "label": "pancreatic gastrinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024638",
  "properties": {
    "xrefs": [
      "GARD:0025441",
      "MEDGEN:1849954",
      "NCIT:C95596",
      "UMLS:C5848106"
    ],
    "synonyms": [
      "pancreatic gastrinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A neuroendocrine tumor arising from the pancreas. It is characterized by inappropriate secretion of gastrin and associated with Zollinger Ellison syndrome. The latter is characterized by the presence of peptic ulcer, gastroesophageal reflux disease, abdominal pain, diarrhea, and malabsorption."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 5436,
      "label": "pancreatic gastrin-producing neuroendocrine tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5434,
        19671
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5580",
          "GARD:0023548",
          "MEDGEN:235080",
          "MESH:D015408",
          "NCIT:C9069",
          "UMLS:C1368066"
        ],
        "synonyms": [
          "gastrin-producing neuroendocrine tumor of pancreas",
          "gastrin-producing neuroendocrine tumour of pancreas",
          "pancreas gastrin-producing neuroendocrine tumor",
          "pancreas gastrin-producing neuroendocrine tumour",
          "pancreatic G-cell tumour",
          "pancreatic gastrin producing NET",
          "pancreatic gastrin producing tumor",
          "pancreatic gastrin producing tumour",
          "pancreatic gastrin-producing neuroendocrine tumor",
          "islet cell tumor, ulcerogenic"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A usually malignant gastrin-producing neuroendocrine tumor arising from the pancreas. It may or may not be associated with inappropriate secretion of gastrin and an associated clinical syndrome."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003525"
    },
    {
      "id": 21182,
      "label": "functional pancreatic neuroendocrine tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19671,
        20359
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022053",
          "MEDGEN:310778",
          "NCIT:C45840",
          "Orphanet:506060",
          "UMLS:C1708107"
        ],
        "synonyms": [
          "functional pancreatic NET",
          "functional pancreatic neuroendocrine tumor",
          "functioning PNET",
          "functioning pancreatic NET",
          "functioning pancreatic endocrine tumor",
          "functioning pancreatic endocrine tumour",
          "functioning pancreatic neuroendocrine tumor",
          "functioning pancreatic neuroendocrine tumour",
          "functioning well differentiated pancreatic endocrine neoplasm",
          "functioning well differentiated pancreatic endocrine tumor",
          "functioning well differentiated pancreatic endocrine tumour",
          "functioning well-differentiated NEN of pancreas",
          "functioning well-differentiated neuroendocrine neoplasm of pancreas",
          "functioning well-differentiated pancreatic NEN",
          "functioning well-differentiated pancreatic neuroendocrine neoplasm",
          "syndromic pancreatic NET",
          "syndromic pancreatic neuroendocrine tumor",
          "syndromic pancreatic neuroendocrine tumour",
          "functioning neuroendocrine tumor of pancreas",
          "functioning neuroendocrine tumour of pancreas"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A low or intermediate grade well differentiated tumor with neuroendocrine differentiation that arises from the pancreas. It is characterized by the presence of a clinical syndrome that results from hormone hypersecretion."
      },
      "child_count": 6,
      "reference_id": "MONDO:0023206"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 5436,
      "label": "pancreatic gastrin-producing neuroendocrine tumor"
    },
    {
      "id": 21182,
      "label": "functional pancreatic neuroendocrine tumor"
    }
  ]
}