{
  "id": 21561,
  "label": "skull neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024653",
  "properties": {
    "xrefs": [
      "GARD:0025448",
      "ICD9:239.2",
      "MEDGEN:11457",
      "MESH:D012888",
      "NCIT:C3375",
      "SCTID:126538005",
      "UMLS:C0037305"
    ],
    "synonyms": [
      "neoplasm of skull",
      "neoplasm of the skull",
      "skull neoplasm",
      "skull tumor",
      "skull tumour",
      "tumor of skull",
      "tumor of the skull",
      "tumour of skull",
      "tumour of the skull"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A benign or malignant neoplasm that affects the bones and structures of the skull."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 7231,
      "label": "head and neck neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0005950",
          "ICD9:239.89",
          "MEDGEN:6728",
          "NCIT:C3077",
          "ONCOTREE:HEADNECK",
          "SCTID:255055008",
          "UMLS:C0018671"
        ],
        "synonyms": [
          "craniocervical region neoplasm",
          "craniocervical region neoplasm (disease)",
          "craniocervical region tumor",
          "craniocervical region tumour",
          "head and neck neoplasm",
          "head and neck neoplasm (excluding central nervous system)",
          "head and neck tumor",
          "head and neck tumour",
          "neoplasm of craniocervical region",
          "neoplasm of head and neck",
          "neoplasm of the head and neck",
          "tumor of craniocervical region",
          "tumor of head and neck",
          "tumor of the head and neck",
          "tumour of craniocervical region",
          "tumour of head and neck",
          "tumour of the head and neck"
        ],
        "definition": "A benign or malignant neoplasm that affects the anatomic structures of the head and neck region. Representative examples of benign neoplasms include salivary gland pleomorphic adenoma and nasal cavity papilloma. Representative examples of malignant neoplasms include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma."
      },
      "child_count": 37,
      "reference_id": "MONDO:0005586"
    },
    {
      "id": 18958,
      "label": "bone neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7061,
        20678
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003820",
          "GARD:0018892",
          "ICD10CM:C40-C41",
          "MEDGEN:488993",
          "NCIT:C9343",
          "ONCOTREE:BONE",
          "Orphanet:68411",
          "UMLS:C2732838"
        ],
        "synonyms": [
          "bone neoplasm",
          "bone neoplasms",
          "bone tissue neoplasm",
          "bone tissue tumor",
          "bone tissue tumour",
          "bone tumor",
          "bone tumors",
          "bone tumour",
          "bone tumours",
          "neoplasm of bone",
          "neoplasm of bone tissue",
          "neoplasm of the bone",
          "osseous neoplasm",
          "osseous tumor",
          "osseous tumour",
          "tumor of bone",
          "tumor of bone tissue",
          "tumor of the bone",
          "tumour of bone",
          "tumour of bone tissue",
          "tumour of the bone",
          "primary bone cancer",
          "primary malignant neoplasm of bone",
          "rare bone tumor",
          "rare bone tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage."
      },
      "child_count": 40,
      "reference_id": "MONDO:0019060"
    },
    {
      "id": 21562,
      "label": "skull disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7061
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:226937",
          "NCIT:C27655",
          "SCTID:118945008",
          "UMLS:C1290854"
        ],
        "synonyms": [
          "disease of skull",
          "disease or disorder of skull",
          "disorder of skull",
          "skull disease",
          "skull disease or disorder",
          "skull disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects structures of the skull."
      },
      "child_count": 6,
      "reference_id": "MONDO:0024654"
    }
  ],
  "children": [
    {
      "id": 4265,
      "label": "skull cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4262,
        7266,
        21561
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1863",
          "GARD:0023073",
          "MEDGEN:1662558",
          "NCIT:C155790",
          "UMLS:C2062986"
        ],
        "synonyms": [
          "cancer of skull",
          "malignant neoplasm of skull",
          "malignant skull neoplasm",
          "skull cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the skull."
      },
      "child_count": 18,
      "reference_id": "MONDO:0002132"
    },
    {
      "id": 4813,
      "label": "skull base neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21561
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3842",
          "GARD:0023244",
          "MEDGEN:138208",
          "MESH:D019292",
          "NCIT:C4676",
          "UMLS:C0376527"
        ],
        "synonyms": [
          "basicranium neoplasm",
          "basicranium neoplasm (disease)",
          "basicranium tumor",
          "basicranium tumour",
          "neoplasm of basicranium",
          "neoplasm of skull base",
          "neoplasm of the skull base",
          "skull base neoplasm",
          "skull base tumor",
          "skull base tumour",
          "tumor of basicranium",
          "tumor of skull base",
          "tumor of the skull base",
          "tumour of basicranium",
          "tumour of skull base",
          "tumour of the skull base",
          "tumours of skull base",
          "skull base cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the skull base."
      },
      "child_count": 5,
      "reference_id": "MONDO:0002785"
    },
    {
      "id": 5651,
      "label": "jugular foramen meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17113,
        21561
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6110",
          "GARD:0023662",
          "MEDGEN:233586",
          "NCIT:C5293",
          "UMLS:C1334298"
        ],
        "synonyms": [
          "jugular foramen meningioma (disease)",
          "meningioma (disease) of jugular foramen",
          "meningioma of jugular Foramen",
          "meningioma of the jugular Foramen"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the jugular foramen."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003771"
    },
    {
      "id": 5835,
      "label": "schwannoma of jugular foramen",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6580,
        21561
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6735",
          "GARD:0023760",
          "MEDGEN:272780",
          "NCIT:C5323",
          "UMLS:C1334300"
        ],
        "synonyms": [
          "jugular Foramen neurilemmoma",
          "jugular foramen schwannoma",
          "neurilemmoma of jugular Foramen",
          "neurilemmoma of the jugular Foramen",
          "schwannoma of the jugular Foramen"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare intracranial schwannoma that affects the jugular foramen."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003980"
    },
    {
      "id": 6984,
      "label": "paranasal sinus neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3922,
        21561
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1350",
          "EFO:0003866",
          "GARD:0024171",
          "HP:0030072",
          "MEDGEN:18296",
          "NCIT:C7488",
          "SCTID:126675008",
          "UMLS:C0030470"
        ],
        "synonyms": [
          "accessory sinus neoplasm",
          "accessory sinus tumor",
          "accessory sinus tumour",
          "neoplasm of accessory sinus",
          "neoplasm of paranasal sinus",
          "neoplasm of the accessory sinus",
          "neoplasm of the paranasal sinus",
          "paranasal sinus neoplasm",
          "paranasal sinus neoplasm (disease)",
          "paranasal sinus neoplasms",
          "paranasal sinus tumor",
          "paranasal sinus tumour",
          "tumor of accessory sinus",
          "tumor of paranasal sinus",
          "tumor of the accessory sinus",
          "tumor of the paranasal sinus",
          "tumour of accessory sinus",
          "tumour of paranasal sinus",
          "tumour of the accessory sinus",
          "tumour of the paranasal sinus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the paranasal sinuses. Representative examples of benign neoplasms include Schneiderian papilloma and salivary gland-type adenoma. Representative examples of malignant neoplasms include carcinoma and lymphoma."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005289"
    },
    {
      "id": 20677,
      "label": "neoplasm of jaw",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8301,
        20434,
        21213,
        21561
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025339",
          "ICD9:239.89",
          "MEDGEN:43991",
          "SCTID:126634001",
          "UMLS:C0022364"
        ],
        "synonyms": [
          "jaw skeleton neoplasm",
          "jaw skeleton neoplasm (disease)",
          "jaw skeleton tumor",
          "jaw skeleton tumour",
          "neoplasm of jaw skeleton",
          "tumor of jaw skeleton",
          "tumour of jaw skeleton"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the jaw skeleton."
      },
      "child_count": 20,
      "reference_id": "MONDO:0021580"
    },
    {
      "id": 21526,
      "label": "orbit neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4171,
        21213,
        21561
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025436",
          "MEDGEN:18190",
          "NCIT:C3290",
          "UMLS:C0029185"
        ],
        "synonyms": [
          "neoplasm of orbit",
          "neoplasm of orbit of skull",
          "neoplasm of the orbit",
          "orbit neoplasm",
          "orbit of skull neoplasm",
          "orbit of skull tumor",
          "orbit of skull tumour",
          "orbit tumor",
          "orbit tumour",
          "orbital neoplasm",
          "orbital neoplasms",
          "orbital tumor",
          "orbital tumour",
          "tumor of orbit",
          "tumor of orbit of skull",
          "tumor of the orbit",
          "tumour of orbit",
          "tumour of orbit of skull",
          "tumour of the orbit"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the orbit."
      },
      "child_count": 6,
      "reference_id": "MONDO:0024611"
    }
  ],
  "roots": [
    {
      "id": 7231,
      "label": "head and neck neoplasm"
    },
    {
      "id": 18958,
      "label": "bone neoplasm"
    },
    {
      "id": 21562,
      "label": "skull disorder"
    }
  ]
}