{
  "id": 21575,
  "label": "Pancoast syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024674",
  "properties": {
    "xrefs": [
      "GARD:0025455",
      "MEDGEN:10553",
      "MESH:D010178",
      "NCIT:C55815",
      "SCTID:278065000",
      "UMLS:C0030271"
    ],
    "synonyms": [
      "Pancoast syndrome",
      "Pancoast's syndrome",
      "Pancoast tumor",
      "Pancoast tumour",
      "Pancoasts syndrome",
      "superior pulmonary sulcus syndrome",
      "syndrome, Pancoast",
      "syndrome, Pancoast's",
      "tumor, Pancoast"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      }
    ],
    "definition": "A rare neoplastic syndrome characterized by obstruction of the thoracic outlet leading to compression of the brachial plexus and vessels within. It is usually caused by a malignant neoplasm in the superior pulmonary sulcus. The most commonly involved neoplasms are non-small cell lung carcinomas. Clinical signs include Horner's syndrome, shoulder pain radiating down the arm in the ulnar distribution followed by edema and atrophy of the affected extremity. Clinical course usually leads to early local invasion of the bony thoracic structures. Prognosis is highly stage-dependent."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 20301,
      "label": "neoplastic syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        21214
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:362147",
          "NCIT:C54705",
          "UMLS:C1882062"
        ],
        "synonyms": [
          "cancer-related syndrome",
          "neoplastic syndrome",
          "tumor syndrome",
          "tumour syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A broad classification for disorders in which the development of neoplasms typically occur in association with a characteristic set of signs or symptoms. These disorders may be inherited or acquired."
      },
      "child_count": 22,
      "reference_id": "MONDO:0021058"
    },
    {
      "id": 21606,
      "label": "secondary neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21214
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1851572",
          "NCIT:C36255",
          "UMLS:C5848363"
        ],
        "synonyms": [
          "secondary neoplasm",
          "secondary tumor",
          "secondary tumour"
        ],
        "definition": "A neoplasm that arises from a pre-existing lower grade lesion, or as a result of a primary lesion that has spread to secondary sites, or due to a complication of a cancer treatment."
      },
      "child_count": 5,
      "reference_id": "MONDO:0024882"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 20301,
      "label": "neoplastic syndrome"
    },
    {
      "id": 21606,
      "label": "secondary neoplasm"
    }
  ]
}