{
  "id": 21577,
  "label": "childhood kidney Wilms tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024676",
  "properties": {
    "xrefs": [
      "GARD:0025457",
      "MEDGEN:232073",
      "NCIT:C27730",
      "UMLS:C1333015"
    ],
    "synonyms": [
      "Wilms tumor",
      "Wilms tumour",
      "kidney Wilms tumor",
      "kidney Wilms tumour",
      "childhood Wilms tumor",
      "childhood Wilms tumour",
      "childhood kidney Wilms tumor",
      "childhood renal Wilms tumor",
      "childhood renal Wilms tumour",
      "childhood renal Wilms' tumor",
      "childhood renal Wilms' tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A Wilms tumor of the kidney which occurs in children."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 18919,
      "label": "kidney Wilms tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4465,
        7641
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2154",
          "DOID:5176",
          "GARD:0007892",
          "ICDO:8960/3",
          "MedDRA:10029145",
          "NANDO:2200043",
          "NCIT:C40407",
          "NORD:1855",
          "ONCOTREE:WT",
          "Orphanet:654",
          "SCTID:302849000"
        ],
        "synonyms": [
          "Wilms tumor",
          "Wilms tumour",
          "Wilms' tumor",
          "Wilms' tumour",
          "Wilms tumor of the kidney",
          "Wilms tumour of the kidney",
          "Wilms' Tumor",
          "Wilms' tumor of the kidney",
          "Wilms' tumour of the kidney",
          "kidney Wilms tumor",
          "nephroblastoma",
          "nephroblastoma, malignant",
          "renal Wilms tumor",
          "renal Wilms tumour",
          "renal Wilms' tumor",
          "renal embryonic tumor",
          "renal embryonic tumour",
          "adult nephroblastoma",
          "adult renal Wilms' tumour",
          "childhood renal Wilms tumor",
          "childhood renal Wilms tumour",
          "childhood renal Wilms' cancer",
          "embryonal nephroma",
          "nonanaplastic renal Wilm's tumor",
          "nonanaplastic renal Wilm's tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An embryonal pediatric tumor of the kidney which may also be seen rarely in adults. The peak incidence of Wilms tumor is between the second and fifth year of life. Microscopically, it is composed of a mixture of cellular elements (blastemal, stromal, and epithelial). The most common sites of metastasis include the regional lymph nodes, lungs, and liver."
      },
      "child_count": 16,
      "reference_id": "MONDO:0019004"
    },
    {
      "id": 22942,
      "label": "childhood malignant kidney neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4465,
        4767,
        8005
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:904186",
          "NCIT:C123907",
          "UMLS:C4086162"
        ],
        "synonyms": [
          "childhood kidney cancer",
          "childhood malignant kidney neoplasm",
          "childhood malignant kidney tumor",
          "childhood malignant kidney tumour",
          "childhood malignant renal neoplasm",
          "childhood malignant renal tumor",
          "childhood malignant renal tumour",
          "kidney cancer of childhood",
          "paediatric kidney cancer",
          "pediatric kidney cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A malignant neoplasm that affects the kidney and occurs in childhood."
      },
      "child_count": 9,
      "reference_id": "MONDO:0036511"
    }
  ],
  "children": [
    {
      "id": 21983,
      "label": "cystic partially differentiated nephroblastoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6170,
        21577
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7571",
          "GARD:0025603",
          "ICDO:8959/1",
          "ICDO:8959/3",
          "MEDGEN:220423",
          "NCIT:C6897",
          "UMLS:C1266139"
        ],
        "synonyms": [
          "cystic partially differentiated nephroblastoma",
          "malignant cystic nephroma",
          "malignant multilocular cystic nephroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A variant of Wilms tumor of the kidney characterized by the presence of cystic spaces separated by septa. The septa contain immature epithelial cells, immature stromal cells, and blastema cells. Surgical resection is usually curative."
      },
      "child_count": 0,
      "reference_id": "MONDO:0030604"
    }
  ],
  "roots": [
    {
      "id": 18919,
      "label": "kidney Wilms tumor"
    },
    {
      "id": 22942,
      "label": "childhood malignant kidney neoplasm"
    }
  ]
}