{
  "id": 21578,
  "label": "pancreatic insulinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024677",
  "properties": {
    "xrefs": [
      "DOID:3892",
      "GARD:0025458",
      "HP:0012197",
      "MEDGEN:43907",
      "MESH:D007340",
      "MedDRA:10022498",
      "NANDO:2200398",
      "NCIT:C95598",
      "SCTID:302822000",
      "UMLS:C0021670",
      "icd11.foundation:193813168"
    ],
    "synonyms": [
      "insulinoma",
      "pancreatic insulinoma",
      "Insulinomas",
      "Insulomas",
      "adenoma, beta cell",
      "adenoma, beta-cell",
      "adenomas, beta-cell",
      "beta cell tumor",
      "beta cell tumour",
      "beta-cell adenoma",
      "beta-cell adenomas",
      "beta-cell tumor",
      "beta-cell tumors",
      "beta-cell tumour",
      "beta-cell tumours",
      "insulin-producing tumour of islet cells",
      "insulinoma tumor suppressor GENE locus",
      "insulinoma tumour suppressor GENE locus",
      "insuloma",
      "islet cell adenoma",
      "tumor, beta-cell",
      "tumors, beta-cell"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "An insulin-producing neuroendocrine tumor arising from the beta cells of the pancreas. Patients exhibit symptoms related to hypoglycemia due to inappropriate secretion of insulin."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6780,
      "label": "pancreatic insulin-producing neuroendocrine tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19671
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000549",
          "GARD:0003010",
          "ICDO:8151/0",
          "ICDO:8151/1",
          "MEDGEN:1844884",
          "NCIT:C3140",
          "Orphanet:97279",
          "UMLS:C5848150"
        ],
        "synonyms": [
          "Beta cell tumor",
          "Beta cell tumor of pancreas",
          "Beta cell tumor of the pancreas",
          "Beta cell tumour",
          "Beta cell tumour of pancreas",
          "Beta cell tumour of the pancreas",
          "beta cell neoplasm",
          "beta cell tumor of the pancreas",
          "beta cell tumour of the pancreas",
          "insulin-producing islet cell tumor",
          "insulin-producing islet cell tumour",
          "insulin-producing tumor of islet cells",
          "insulin-producing tumor of the islet cells",
          "insulin-producing tumour of islet cells",
          "insulin-producing tumour of the islet cells",
          "pancreatic Beta cell tumor",
          "pancreatic Beta cell tumour",
          "pancreatic insulin producing NET",
          "pancreatic insulin producing neoplasm",
          "pancreatic insulin producing tumor",
          "pancreatic insulin producing tumour",
          "pancreatic insulin-producing neuroendocrine tumor",
          "pancreatic insulin-producing tumor",
          "pancreatic insulin-producing tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An insulin-producing neuroendocrine tumor arising from the beta cells of the pancreas. It may or may not be associated with inappropriate secretion of insulin and an associated clinical syndrome."
      },
      "child_count": 1,
      "reference_id": "MONDO:0005048"
    },
    {
      "id": 21182,
      "label": "functional pancreatic neuroendocrine tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19671,
        20359
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022053",
          "MEDGEN:310778",
          "NCIT:C45840",
          "Orphanet:506060",
          "UMLS:C1708107"
        ],
        "synonyms": [
          "functional pancreatic NET",
          "functional pancreatic neuroendocrine tumor",
          "functioning PNET",
          "functioning pancreatic NET",
          "functioning pancreatic endocrine tumor",
          "functioning pancreatic endocrine tumour",
          "functioning pancreatic neuroendocrine tumor",
          "functioning pancreatic neuroendocrine tumour",
          "functioning well differentiated pancreatic endocrine neoplasm",
          "functioning well differentiated pancreatic endocrine tumor",
          "functioning well differentiated pancreatic endocrine tumour",
          "functioning well-differentiated NEN of pancreas",
          "functioning well-differentiated neuroendocrine neoplasm of pancreas",
          "functioning well-differentiated pancreatic NEN",
          "functioning well-differentiated pancreatic neuroendocrine neoplasm",
          "syndromic pancreatic NET",
          "syndromic pancreatic neuroendocrine tumor",
          "syndromic pancreatic neuroendocrine tumour",
          "functioning neuroendocrine tumor of pancreas",
          "functioning neuroendocrine tumour of pancreas"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A low or intermediate grade well differentiated tumor with neuroendocrine differentiation that arises from the pancreas. It is characterized by the presence of a clinical syndrome that results from hormone hypersecretion."
      },
      "child_count": 6,
      "reference_id": "MONDO:0023206"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6780,
      "label": "pancreatic insulin-producing neuroendocrine tumor"
    },
    {
      "id": 21182,
      "label": "functional pancreatic neuroendocrine tumor"
    }
  ]
}