{
  "id": 21582,
  "label": "benign synovial neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024715",
  "properties": {
    "xrefs": [
      "ICDO:9040/0",
      "MEDGEN:113161",
      "NCIT:C3829",
      "UMLS:C0221289"
    ],
    "synonyms": [
      "benign neoplasm of synovium",
      "benign neoplasm of the synovium",
      "benign synovial neoplasm",
      "benign synovial tumor",
      "benign synovial tumour",
      "benign synovioma",
      "benign synovium neoplasm",
      "benign tumor of synovium",
      "benign tumor of the synovium",
      "benign tumour of synovium",
      "benign tumour of the synovium",
      "synovioma, benign",
      "synovium neoplasm, benign"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A benign neoplasm arising from the synovial membrane. Examples include the diffuse giant cell tumor of tendon sheath and localized giant cell tumor of tendon sheath."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 4597,
      "label": "synovium neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7941,
        8264,
        23662
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:315",
          "MEDGEN:99197",
          "NCIT:C8964",
          "UMLS:C0476203"
        ],
        "synonyms": [
          "neoplasm of synovial membrane of synovial joint",
          "neoplasm of synovium",
          "neoplasm of the synovium",
          "synovial membrane of synovial joint neoplasm",
          "synovial membrane of synovial joint neoplasm (disease)",
          "synovial membrane of synovial joint tumor",
          "synovial membrane of synovial joint tumour",
          "synovial neoplasm",
          "synovial neoplasm (morphologic abnormality)",
          "synovial neoplasm NOS (morphologic abnormality)",
          "synovial tumor",
          "synovial tumour",
          "tumor of synovial membrane of synovial joint",
          "tumor of synovium",
          "tumor of the synovium",
          "tumour of synovial membrane of synovial joint",
          "tumour of synovium",
          "tumour of the synovium"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A benign or malignant soft tissue neoplasm arising exclusively from the synovial membrane. Examples include the diffuse giant cell tumor of tendon sheath, localized giant cell tumor of tendon sheath, and malignant giant cell tumor of tendon sheath."
      },
      "child_count": 9,
      "reference_id": "MONDO:0002528"
    },
    {
      "id": 23337,
      "label": "benign soft tissue neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3054,
        7941
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8800/0",
          "MEDGEN:83151",
          "NCIT:C4242",
          "SCTID:92069005",
          "UMLS:C0334450"
        ],
        "synonyms": [
          "benign neoplasm of soft tissue",
          "benign neoplasm of the soft tissue",
          "benign soft tissue neoplasm",
          "benign soft tissue tumor",
          "benign soft tissue tumour",
          "benign tumor of soft tissue",
          "benign tumor of the soft tissue",
          "benign tumour of soft tissue",
          "benign tumour of the soft tissue",
          "soft tissue neoplasm, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm that arises from the soft tissue."
      },
      "child_count": 20,
      "reference_id": "MONDO:0044335"
    }
  ],
  "children": [
    {
      "id": 4489,
      "label": "tenosynovial giant cell tumor, localized type",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4592,
        21582
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2701",
          "ICD9:727.02",
          "MEDGEN:154413",
          "NCIT:C6532",
          "SCTID:95413004",
          "UMLS:C0588125"
        ],
        "synonyms": [
          "localised giant cell neoplasm of Tenosynovium",
          "localised giant cell neoplasm of tendon sheath",
          "localised giant cell neoplasm of the Tenosynovium",
          "localised giant cell tumour of Tenosynovium",
          "localised giant cell tumour of tendon sheath",
          "localised giant cell tumour of the Tenosynovium",
          "localised tenosynovial giant cell neoplasm",
          "localised tenosynovial giant cell tumour",
          "localized giant cell neoplasm of Tenosynovium",
          "localized giant cell neoplasm of tendon sheath",
          "localized giant cell neoplasm of the Tenosynovium",
          "localized giant cell tumor of Tenosynovium",
          "localized giant cell tumor of tendon sheath",
          "localized giant cell tumor of the Tenosynovium",
          "localized tenosynovial giant cell neoplasm",
          "localized tenosynovial giant cell tumor",
          "nodular tenosynovitis",
          "synovioma, benign (morphologic abnormality)",
          "tenosynovial giant cell tumor, localized type",
          "benign synovioma",
          "benign tumor of synovium",
          "benign tumour of synovium"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A well-circumscribed, lobulated tumor, completely or partially covered by a fibrous capsule. It usually arises in the fingers. It is characterized by the presence of mononuclear cells, multinucleated osteoclast-like giant cells, hemosiderin-laden macrophages, foam cells, and an inflammatory infiltrate. The tumor is slow-growing, usually developing over several years. Clinical presentation includes painless edema of the affected site."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002399"
    },
    {
      "id": 5912,
      "label": "tendon sheath lipoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6833,
        21582,
        21600
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7016",
          "MEDGEN:277806",
          "NCIT:C6499",
          "UMLS:C1336703"
        ],
        "synonyms": [
          "lipoma of tendon sheath",
          "lipoma of the tendon sheath",
          "tendon sheath lipoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign tumor, composed of mature adipocytes, that arises within the tendon sheath."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004076"
    },
    {
      "id": 6320,
      "label": "synovial angioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7994,
        21582
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8274",
          "MEDGEN:234375",
          "NCIT:C6525",
          "UMLS:C1336546"
        ],
        "synonyms": [
          "angioma of synovium",
          "angioma of the synovium",
          "hemangioma of layer of synovial tissue",
          "hemangioma of synovium",
          "hemangioma of the synovium",
          "layer of synovial tissue hemangioma",
          "synovial hemangioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A rare hemangioma arising from synovium lining surfaces."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004519"
    },
    {
      "id": 21580,
      "label": "tenosynovial giant cell tumor, diffuse type",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4592,
        21582
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2702",
          "DOID:9898",
          "GARD:0007396",
          "ICD10CM:M12.2",
          "ICD9:719.2",
          "ICD9:719.20",
          "ICD9:719.28",
          "ICDO:9251/0",
          "MEDGEN:11691",
          "MESH:D013586",
          "NCIT:C3401",
          "NORD:1916",
          "ONCOTREE:TGCT",
          "Orphanet:66627",
          "SCTID:95412009",
          "UMLS:C0039106"
        ],
        "synonyms": [
          "TGCT",
          "TSGCT",
          "Tenosynovial Giant Cell Tumor",
          "diffuse giant cell neoplasm of Tenosynovium",
          "diffuse giant cell neoplasm of tendon sheath",
          "diffuse giant cell neoplasm of the Tenosynovium",
          "diffuse giant cell tumor of Tenosynovium",
          "diffuse giant cell tumor of tendon sheath",
          "diffuse giant cell tumor of the Tenosynovium",
          "diffuse giant cell tumour of Tenosynovium",
          "diffuse giant cell tumour of tendon sheath",
          "diffuse giant cell tumour of the Tenosynovium",
          "diffuse tenosynovial giant cell neoplasm",
          "diffuse tenosynovial giant cell tumor",
          "diffuse tenosynovial giant cell tumour",
          "pigmented villonodular synovitis",
          "tenosynovial giant cell tumor, diffuse type",
          "diffuse pigmented villonodular synovitis",
          "diffuse-type GCT",
          "diffuse-type giant cell tumor",
          "diffuse-type giant cell tumour",
          "localised pigmented villonodular synovitis",
          "localized pigmented villonodular synovitis",
          "tenosynovial giant cell tumor",
          "tenosynovial giant cell tumor diffuse type",
          "tenosynovial giant cell tumors",
          "tenosynovial giant cell tumour",
          "tenosynovial giant cell tumour diffuse type",
          "tenosynovial giant cell tumours",
          "villonodular synovitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A locally aggressive, diffusely infiltrating tumor, arising in the tendon sheath. It is composed of synovial-like mononuclear cells, hemosiderin-laden macrophages, foam cells, and inflammatory cells. Multinucleated osteoclast-like giant cells are usually present, although in a minority of cases they may be absent or rare. It predominantly affects young adults. Symptoms include joint swelling, pain, and joint effusion."
      },
      "child_count": 0,
      "reference_id": "MONDO:0024686"
    }
  ],
  "roots": [
    {
      "id": 4597,
      "label": "synovium neoplasm"
    },
    {
      "id": 23337,
      "label": "benign soft tissue neoplasm"
    }
  ]
}