{
  "id": 21603,
  "label": "metastatic carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024879",
  "properties": {
    "xrefs": [
      "ICDO:8010/6",
      "MEDGEN:235141",
      "NCIT:C3482",
      "UMLS:C1384494",
      "icd11.foundation:553023050"
    ],
    "synonyms": [
      "metastatic carcinoma"
    ],
    "definition": "A carcinoma which has spread from the original site of growth to another anatomic site."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 21602,
      "label": "secondary carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        21605
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:88450",
          "NCIT:C36310",
          "UMLS:C0085668"
        ],
        "synonyms": [
          "secondary carcinoma"
        ],
        "definition": "A carcinoma that arises from a pre-existing lower grade epithelial lesion, or as a result of a primary carcinoma that has spread to secondary sites, or due to a complication of a cancer treatment."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024878"
    },
    {
      "id": 21604,
      "label": "metastatic malignant neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21605,
        21607
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:422475",
          "NCIT:C36263",
          "UMLS:C2939419",
          "icd11.foundation:1399468320"
        ],
        "synonyms": [
          "malignant metastatic neoplasm",
          "metastatic cancer",
          "metastatic malignant neoplasm",
          "metastatic neoplasm, malignant"
        ],
        "definition": "A malignant tumor that has spread from its original (primary) site of growth to another site close to or distant from the primary site."
      },
      "child_count": 14,
      "reference_id": "MONDO:0024880"
    }
  ],
  "children": [
    {
      "id": 6587,
      "label": "Krukenberg carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4787,
        6819,
        21603
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9597",
          "EFO:1000316",
          "GARD:0008627",
          "MEDGEN:9652",
          "MESH:D007725",
          "NCIT:C3153",
          "SCTID:359987004",
          "UMLS:C0022790"
        ],
        "synonyms": [
          "Krukenberg neoplasm",
          "Krukenberg tumor",
          "Krukenberg tumour",
          "Krukenberg’s tumor",
          "Krukenberg’s tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Metastatic signet-ring cell carcinoma to the ovary. The primary site is the gastrointestinal tract or breast."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004829"
    },
    {
      "id": 21598,
      "label": "metastatic carcinoma in the adrenal medulla",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6024,
        21603
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025469",
          "MEDGEN:277362",
          "NCIT:C9276",
          "UMLS:C1334717"
        ],
        "synonyms": [
          "metastatic carcinoma in the adrenal medulla",
          "metastatic carcinoma to the adrenal medulla"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A carcinoma that has spread to the adrenal medulla from an adjacent or distant anatomic site."
      },
      "child_count": 0,
      "reference_id": "MONDO:0024868"
    },
    {
      "id": 21608,
      "label": "metastatic carcinoma in the bone",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4505,
        21603
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025471",
          "MEDGEN:195970",
          "NCIT:C36082",
          "UMLS:C0700110"
        ],
        "synonyms": [
          "metastatic carcinoma in the bone",
          "metastatic carcinoma to the bone"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A carcinoma that has spread to the bone from another, primary anatomic site. Bone is one of the most frequent sites of metastatic carcinoma. Common sites of origin include lung, breast, and prostate."
      },
      "child_count": 0,
      "reference_id": "MONDO:0024884"
    },
    {
      "id": 23474,
      "label": "metastatic squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6823,
        21603
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:90749",
          "NCIT:C4104",
          "SCTID:403906006",
          "UMLS:C0334246"
        ],
        "synonyms": [
          "Metastatic squamous cell carcinoma"
        ],
        "definition": "A squamous cell carcinoma which has spread from its original site of growth to another anatomic site."
      },
      "child_count": 0,
      "reference_id": "MONDO:0044907"
    }
  ],
  "roots": [
    {
      "id": 21602,
      "label": "secondary carcinoma"
    },
    {
      "id": 21604,
      "label": "metastatic malignant neoplasm"
    }
  ]
}