{
  "id": 21605,
  "label": "secondary malignant neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024881",
  "properties": {
    "xrefs": [
      "EFO:0009812",
      "ICD9:198.89",
      "ICD9:199.1",
      "MEDGEN:473807",
      "NCIT:C4968",
      "SCTID:128462008",
      "UMLS:C3266877"
    ],
    "synonyms": [
      "secondary cancer",
      "secondary malignancy",
      "secondary malignant neoplasm"
    ],
    "definition": "A malignant neoplasm that arises from a pre-existing lower grade lesion, or as a result of a primary lesion that has spread to secondary sites, or due to a complication of a cancer treatment."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6733,
      "label": "cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050686",
          "DOID:0050687",
          "DOID:162",
          "ICD9:195.8",
          "ICD9:199",
          "ICD9:199.1",
          "ICDO:8000/3",
          "MEDGEN:14297",
          "NCIT:C9305",
          "ONCOTREE:MT",
          "SCTID:363346000",
          "UMLS:C0006826",
          "birnlex:406"
        ],
        "synonyms": [
          "CA",
          "cancer",
          "cell type cancer",
          "malignancy",
          "malignant growth",
          "malignant neoplasm",
          "malignant neoplasm (disease)",
          "malignant neoplastic disease",
          "malignant tumor",
          "malignant tumour",
          "neoplasm (disease), malignant",
          "neoplasm, malignant",
          "MT"
        ],
        "definition": "A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas."
      },
      "child_count": 33,
      "reference_id": "MONDO:0004992"
    },
    {
      "id": 21606,
      "label": "secondary neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21214
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1851572",
          "NCIT:C36255",
          "UMLS:C5848363"
        ],
        "synonyms": [
          "secondary neoplasm",
          "secondary tumor",
          "secondary tumour"
        ],
        "definition": "A neoplasm that arises from a pre-existing lower grade lesion, or as a result of a primary lesion that has spread to secondary sites, or due to a complication of a cancer treatment."
      },
      "child_count": 5,
      "reference_id": "MONDO:0024882"
    }
  ],
  "children": [
    {
      "id": 21602,
      "label": "secondary carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        21605
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:88450",
          "NCIT:C36310",
          "UMLS:C0085668"
        ],
        "synonyms": [
          "secondary carcinoma"
        ],
        "definition": "A carcinoma that arises from a pre-existing lower grade epithelial lesion, or as a result of a primary carcinoma that has spread to secondary sites, or due to a complication of a cancer treatment."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024878"
    },
    {
      "id": 21604,
      "label": "metastatic malignant neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21605,
        21607
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:422475",
          "NCIT:C36263",
          "UMLS:C2939419",
          "icd11.foundation:1399468320"
        ],
        "synonyms": [
          "malignant metastatic neoplasm",
          "metastatic cancer",
          "metastatic malignant neoplasm",
          "metastatic neoplasm, malignant"
        ],
        "definition": "A malignant tumor that has spread from its original (primary) site of growth to another site close to or distant from the primary site."
      },
      "child_count": 14,
      "reference_id": "MONDO:0024880"
    }
  ],
  "roots": [
    {
      "id": 6733,
      "label": "cancer"
    },
    {
      "id": 21606,
      "label": "secondary neoplasm"
    }
  ]
}