{
  "id": 21609,
  "label": "malignant ovarian serous tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0024885",
  "properties": {
    "xrefs": [
      "GARD:0025472",
      "MEDGEN:309396",
      "NCIT:C40025",
      "UMLS:C1518234"
    ],
    "synonyms": [
      "malignant ovarian serous tumor",
      "ovarian serous tumor, malignant"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "An invasive malignant neoplasm that arises from the ovary and is characterized by the presence of malignant epithelial cells that, in well differentiated tumors, resemble the epithelium of the fallopian tube or, in poorly differentiated tumors, show anaplastic features and marked nuclear atypia. It includes serous adenocarcinoma and serous adenocarcinofibroma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 18447,
      "label": "malignant epithelial tumor of ovary",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4347,
        6734,
        9481
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2151",
          "GARD:0009362",
          "MEDGEN:577291",
          "MESH:C538090",
          "NCIT:C40026",
          "Orphanet:398934",
          "SCTID:254849005",
          "UMLS:C0346161"
        ],
        "synonyms": [
          "epithelial cancer of ovary",
          "malignant ovarian epithelial tumor",
          "malignant ovarian epithelial tumour",
          "malignant ovarian surface epithelial-stromal neoplasm",
          "malignant ovarian surface epithelial-stromal tumor",
          "malignant ovarian surface epithelial-stromal tumour",
          "ovarian epithelial cancer",
          "ovarian epithelial tumor, malignant",
          "ovarian malignant epithelial tumor",
          "ovarian malignant epithelial tumour",
          "ovarian stromal cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An invasive malignant tumor that originates from the surface epithelium of the ovary. It is composed of malignant epithelial cells and stroma. Representative examples include serous adenocarcinoma, mucinous adenocarcinoma, endometrioid adenocarcinoma, clear cell adenocarcinoma, and malignant Brenner tumor."
      },
      "child_count": 18,
      "reference_id": "MONDO:0018364"
    },
    {
      "id": 22963,
      "label": "ovarian serous tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4347,
        22964
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:141653",
          "NCIT:C8431",
          "UMLS:C0476122"
        ],
        "synonyms": [
          "ovarian serous neoplasm",
          "ovarian serous tumor",
          "serous neoplasm of ovary",
          "serous neoplasm of the ovary",
          "serous tumor of ovary",
          "serous tumor of the ovary",
          "serous tumour of ovary",
          "serous tumour of the ovary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign, borderline, or malignant epithelial tumor of the ovary characterized by the presence of neoplastic epithelial cells that, in well differentiated tumors, resemble the epithelial cells of the fallopian tube and, in poorly differentiated tumors, show anaplastic features. Approximately thirty to fifty percent of the tumors are bilateral. Grossly, the better differentiated tumors consist of cystic masses, usually unilocular, containing a clear but sometimes viscous fluid. Papillary formations are often present. The more malignant tumors tend to be solid and invasive, with areas of necrosis and hemorrhage."
      },
      "child_count": 4,
      "reference_id": "MONDO:0037255"
    }
  ],
  "children": [
    {
      "id": 6927,
      "label": "ovarian serous adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4787,
        6974,
        21609
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050933",
          "DOID:5744",
          "EFO:0002917",
          "GARD:0024164",
          "MEDGEN:233278",
          "NCIT:C7550",
          "ONCOTREE:SOC",
          "UMLS:C1335177"
        ],
        "synonyms": [
          "ovarian serous adenocarcinoma",
          "ovarian serous carcinoma",
          "ovary serous adenocarcinoma",
          "serous adenocarcinoma of ovary",
          "serous adenocarcinoma of the ovary",
          "serous carcinoma of ovary",
          "serous carcinoma of the ovary",
          "malignant ovarian serous tumour",
          "serous ovarian cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An adenocarcinoma that arises from the ovary and is characterized by the presence of malignant epithelial cells that, in well differentiated tumors, resemble the epithelium of the fallopian tube or, in poorly differentiated tumors, show anaplastic features and marked nuclear atypia."
      },
      "child_count": 9,
      "reference_id": "MONDO:0005211"
    }
  ],
  "roots": [
    {
      "id": 18447,
      "label": "malignant epithelial tumor of ovary"
    },
    {
      "id": 22963,
      "label": "ovarian serous tumor"
    }
  ]
}