{
  "id": 21746,
  "label": "HHV-6 encephalitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0027029",
  "properties": {
    "xrefs": [
      "GARD:0009667",
      "MEDGEN:363034",
      "UMLS:C1955629"
    ],
    "synonyms": [
      "Human Herpesvirus 6 encephalitis",
      "Variant A or HHV-6A",
      "Variant B or HHV-6B"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "HHV-6 encephalitis refers to inflammation of the brain due to an infection with human herpesvirus 6. People who have undergone allogeneic hematopoietic cell transplantation are at an increased risk for developing HHV-6 encephalitis, particularly when umbilical cord blood stem cells are used. People with immune system disorders may also be at an increased risk for developing this infection. Signs and symptoms vary, but often include confusion, anterograde amnesia (difficulty learning new information following the onset of amnesia), short-term memory loss, and seizures.Diagnosis often involves lumbar puncture, virus testing, and MRI. EEG 's may also be recommendedwhen seizures are suspected. HHV-6 encephalitis is treated with an antiviral agent with activity against HHV-6. Long term outlook (chance of full recovery) can vary considerably depending individual patient factors."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7544,
      "label": "roseolovirus infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7411
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007474",
          "MEDGEN:83999",
          "MESH:D019349",
          "UMLS:C0376549"
        ],
        "synonyms": [
          "Roseolovirus caused disease or disorder",
          "Roseolovirus disease or disorder",
          "Roseolovirus infectious disease"
        ],
        "definition": "Infection with roseolovirus, the most common in humans being exanthema subitum, a benign disease of infants and young children."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005949"
    },
    {
      "id": 7600,
      "label": "viral encephalitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19721,
        21351,
        24062
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:646",
          "EFO:0007538",
          "GARD:0019433",
          "MEDGEN:116719",
          "MedDRA:10058805",
          "NCIT:C35302",
          "Orphanet:98252",
          "SCTID:34476008",
          "UMLS:C0243010"
        ],
        "synonyms": [
          "Viruses caused encephalitis",
          "Viruses encephalitis",
          "viral encephalitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Encephalitis resulting from viral infection."
      },
      "child_count": 36,
      "reference_id": "MONDO:0006009"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7544,
      "label": "roseolovirus infectious disease"
    },
    {
      "id": 7600,
      "label": "viral encephalitis"
    }
  ]
}