{
  "id": 21769,
  "label": "generalized lipodystrophy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0027766",
  "properties": {
    "xrefs": [
      "DOID:0080298",
      "GARD:0027920",
      "HP:0009064",
      "MEDGEN:1369615",
      "NCIT:C131815",
      "UMLS:C4317112"
    ],
    "synonyms": [
      "complete generalised lipodystrophy",
      "complete generalized lipodystrophy"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "Almost complete absence of subcutaneous and/or visceral adipose tissue."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 8053,
      "label": "lipodystrophy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6795,
        6820
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:811",
          "EFO:1000727",
          "GARD:0027051",
          "HP:0009125",
          "ICD9:272.6",
          "MEDGEN:6111",
          "MESH:D008060",
          "NANDO:1200858",
          "NANDO:2100147",
          "NANDO:2200404",
          "NCIT:C97093",
          "SCTID:71325002",
          "UMLS:C0023787",
          "Wikipedia:Lipodystrophy"
        ],
        "synonyms": [
          "lipodsystrophic syndrome",
          "lipodsystrophic syndromes",
          "lipodystrophy",
          "lipodystrophy (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A congenital or acquired disorder characterized by abnormal loss or redistribution of the adipose tissue in the body."
      },
      "child_count": 10,
      "reference_id": "MONDO:0006573"
    }
  ],
  "children": [
    {
      "id": 8021,
      "label": "congenital generalized lipodystrophy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19731,
        21769
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050585",
          "EFO:1000681",
          "GARD:0024436",
          "HP:0009059",
          "MEDGEN:67438",
          "NANDO:1200859",
          "NORD:998",
          "OMIMPS:608594",
          "SCTID:284449005",
          "UMLS:C0221032"
        ],
        "synonyms": [
          "congenital generalised lipodystrophy (disease)",
          "congenital generalized lipodystrophy",
          "congenital generalized lipodystrophy (disease)",
          "familial generalised lipodystrophy",
          "familial generalized lipodystrophy",
          "hereditary generalised lipodystrophy",
          "hereditary generalized lipodystrophy",
          "lipodystrophy, congenital generalised",
          "lipodystrophy, congenital generalized"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An extremely rare autosomal recessive condition, characterized by an extreme scarcity of fat in the subcutaneous tissues."
      },
      "child_count": 10,
      "reference_id": "MONDO:0006536"
    },
    {
      "id": 19063,
      "label": "acquired generalized lipodystrophy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19733,
        21769
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080300",
          "GARD:0012603",
          "MEDGEN:543499",
          "NANDO:1200860",
          "NCIT:C131089",
          "Orphanet:79086",
          "SCTID:86907008",
          "UMLS:C0271693"
        ],
        "synonyms": [
          "Lawrence syndrome",
          "Lawrence-Seip syndrome",
          "acquired generalized lipodystrophy",
          "acquired lipoatrophic diabetes"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Acquired generalized lipodystrophy belongs to a group of lipodystrophic syndromes characterized by loss of adipose tissue, and is a syndrome of insulin resistance that leads to increased cardiovascular risk. Acquired generalized lipodystrophy is related to a selective loss of subcutaneous adipose tissue occurring exclusively at the extremities (face, legs, arms, palms and sometimes soles)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019193"
    }
  ],
  "roots": [
    {
      "id": 8053,
      "label": "lipodystrophy"
    }
  ]
}