{
  "id": 21820,
  "label": "hereditary glaucoma, primary closed-angle",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0030038",
  "properties": {
    "xrefs": [
      "GARD:0027267",
      "MEDGEN:1712967",
      "OMIM:618880",
      "UMLS:C5394374"
    ],
    "synonyms": [
      "GLCC",
      "glaucoma, primary closed-angle",
      "hereditary primary angle-closure glaucoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ]
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4044,
      "label": "primary angle-closure glaucoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3930
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1405",
          "EFO:1001506",
          "ICD10CM:H40.2",
          "ICD9:365.2",
          "ICD9:365.20",
          "MEDGEN:42225",
          "NCIT:C34640",
          "SCTID:392288006",
          "UMLS:C0017606"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "An angle-closure glaucoma characterized by closure of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Primary angle-closure glaucoma has symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Primary angle closure glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component."
      },
      "child_count": 5,
      "reference_id": "MONDO:0001868"
    },
    {
      "id": 18318,
      "label": "hereditary glaucoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6774
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0002486",
          "MEDGEN:777991",
          "MESH:C580055",
          "Orphanet:359",
          "UMLS:C3711383"
        ],
        "synonyms": [
          "hereditary glaucoma (disease)",
          "glaucoma, hereditary"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Hereditary glaucoma is a clinically diverse group of rare eye disorders with genetic predisposition characterized by elevated intraocular pressure (IOP) and glaucomatous changes of the optic nerve head, leading to field defects, visual loss and blindness. Hereditary glaucoma can be sub-classified as primary (congenital glaucoma, juvenile glaucoma) or secondary according to the presence or absence of systemic or other ocular anomalies (iridogoniodysgenesis, Stickler syndrome, Coats syndrome). The clinical presentation is variable and is based on age, severity of glaucoma, presence of ocular abnormalities and development of secondary IOP related abnormalities."
      },
      "child_count": 24,
      "reference_id": "MONDO:0018174"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4044,
      "label": "primary angle-closure glaucoma"
    },
    {
      "id": 18318,
      "label": "hereditary glaucoma"
    }
  ]
}