{
  "id": 22242,
  "label": "Olmsted syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0031421",
  "properties": {
    "xrefs": [
      "DOID:0112011",
      "GARD:0004075",
      "MEDGEN:590661",
      "MedDRA:10068842",
      "OMIMPS:614594",
      "Orphanet:659",
      "UMLS:C0406761"
    ],
    "synonyms": [
      "mutilating palmoplantar hyperkeratosis with periorificial keratotic plaques",
      "palmoplantar and periorificial keratoderma",
      "palmoplantar keratoderma, mutilating, with periorificial keratotic plaques"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A hereditary palmoplantar keratoderma characterized by the combination of bilateral mutilating transgredient palmoplantar keratoderma and periorificial keratotic plaques."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 19132,
      "label": "hereditary palmoplantar keratoderma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8066,
        19129,
        23867
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018988",
          "ICD9:757.39",
          "MEDGEN:590657",
          "Orphanet:79357",
          "SCTID:239066003",
          "UMLS:C0406757",
          "icd11.foundation:1941547119"
        ],
        "synonyms": [
          "hereditary PPK",
          "hereditary keratosis palmoplantaris",
          "hereditary palmoplantar hyperkeratosis",
          "hereditary palmoplantar keratosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An instance of palmoplantar keratosis that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 24,
      "reference_id": "MONDO:0019272"
    }
  ],
  "children": [
    {
      "id": 11644,
      "label": "Olmsted syndrome, X-linked",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        22242
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0112012",
          "GARD:0015273",
          "MEDGEN:813075",
          "OMIM:300918",
          "UMLS:C3806745"
        ],
        "synonyms": [
          "Olmsted syndrome, X-linked",
          "Olmsted syndrome, X-linked, X-linked recessive",
          "palmoplantar keratoderma, mutilating, with periorificial keratotic plaques, X-linked"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0010486"
    },
    {
      "id": 22149,
      "label": "Olmsted syndrome 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        22242
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016437",
          "MEDGEN:1779902",
          "OMIM:619208",
          "UMLS:C5543096"
        ],
        "synonyms": [
          "OLMS2",
          "Olmsted syndrome 2",
          "palmoplantar keratoderma, mutilating, with periorificial keratotic plaques 2"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0030961"
    },
    {
      "id": 24033,
      "label": "Olmsted syndrome 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        22242
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0112013",
          "GARD:0015818",
          "MEDGEN:1778121",
          "OMIM:614594",
          "UMLS:C5542829"
        ],
        "synonyms": [
          "Olmsted syndrome",
          "palmoplantar keratoderma, mutilating, with periorificial keratotic plaques 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Any Olmsted syndrome in which the cause of the disease is a variation in the TRPV3 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100296"
    }
  ],
  "roots": [
    {
      "id": 19132,
      "label": "hereditary palmoplantar keratoderma"
    }
  ]
}