{
  "id": 22476,
  "label": "hypothyroidism, congenital, nongoitrous, 7",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0032819",
  "properties": {
    "xrefs": [
      "DOID:0111836",
      "GARD:0016914",
      "MEDGEN:349957",
      "OMIM:618573",
      "Orphanet:99832",
      "SCTID:725462002",
      "UMLS:C1861106"
    ],
    "synonyms": [
      "TRH resistance syndrome",
      "central hypothyroidism due to TRH receptor deficiency",
      "hypothyroidism, congenital, nongoitrous, 7",
      "resistance to thyrotropin-releasing hormone syndrome",
      "CHNG7",
      "HYPOTHYROIDISM, CONGENITAL, NONGOITROUS, 7",
      "thyrotropin-releasing hormone resistance, generalised",
      "thyrotropin-releasing hormone resistance, generalized"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ]
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 2710,
      "label": "hypothyroidism, congenital, nongoitrous",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        18613
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022704",
          "OMIMPS:275200"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 18,
      "reference_id": "MONDO:0000045"
    },
    {
      "id": 16927,
      "label": "central congenital hypothyroidism",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16926
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0012280",
          "MEDGEN:927869",
          "NANDO:1200390",
          "NANDO:2200332",
          "NANDO:2200340",
          "NCIT:C113144",
          "Orphanet:226298",
          "UMLS:C4302200",
          "icd11.foundation:848364569"
        ],
        "synonyms": [
          "TSH deficiency",
          "central hypothyroidism",
          "hypothalamic-pituitary hypothyroidism",
          "secondary hypothyroidism",
          "thyroid stimulating hormone deficiency",
          "thyrotropin deficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Central or secondary congenital hypothyroidism is a type of permanent congenital hypothyroidism characterized by permanent thyroid hormone deficiency that is present from birth and secondary to a disorder in the thyroid-stimulating hormone (TSH) - thyrotropin-releasing hormone (TRH) system."
      },
      "child_count": 5,
      "reference_id": "MONDO:0016410"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 2710,
      "label": "hypothyroidism, congenital, nongoitrous"
    },
    {
      "id": 16927,
      "label": "central congenital hypothyroidism"
    }
  ]
}