{
  "id": 22746,
  "label": "radiation-induced plexopathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0033838",
  "properties": {
    "xrefs": [
      "GARD:0022137",
      "MEDGEN:1809151",
      "Orphanet:521123",
      "UMLS:C5681446"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A rare radiation-induced disorder characterized by impairment of the peripheral nervous system at the level of the brachial or lumbosacral plexus following radiation therapy. Onset of symptoms can occur between several months up to decades after the last dose of radiation. Patients with radiation-induced brachial plexopathy typically present with mostly unilateral progressive paresthesia, followed by weakness, atrophy, and pain. Symptoms in radiation-induced lumbosacral plexopathy include more variable combinations of numbness, paresthesia, pain, and weakness, and are more often bilateral."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16613,
      "label": "acquired peripheral neuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6950
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1842976",
          "Orphanet:182086",
          "UMLS:C5680596"
        ],
        "synonyms": [
          "acquired peripheral neuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An instance of peripheral neuropathy that is acquired during the lifetime of the individual."
      },
      "child_count": 12,
      "reference_id": "MONDO:0015923"
    },
    {
      "id": 21410,
      "label": "nerve plexus disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6950
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3688",
          "EFO:0009559",
          "GARD:0025398",
          "MEDGEN:543047",
          "NCIT:C27744",
          "SCTID:2231001",
          "UMLS:C0270891"
        ],
        "synonyms": [
          "disease of nerve plexus",
          "disease or disorder of nerve plexus",
          "disorder of nerve plexus",
          "nerve plexus disease",
          "nerve plexus disease or disorder",
          "nerve plexus disorder",
          "plexopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disease that involves the nerve plexus."
      },
      "child_count": 4,
      "reference_id": "MONDO:0024432"
    },
    {
      "id": 24354,
      "label": "radiation-induced neuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6950,
        23212
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:G62.8",
          "SCTID:445339002"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A peripheral neuropathy caused by exposure to radiation, resulting in damage to one or more peripheral nerves."
      },
      "child_count": 2,
      "reference_id": "MONDO:0100635"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16613,
      "label": "acquired peripheral neuropathy"
    },
    {
      "id": 21410,
      "label": "nerve plexus disorder"
    },
    {
      "id": 24354,
      "label": "radiation-induced neuropathy"
    }
  ]
}