{
  "id": 22909,
  "label": "parenteral nutrition-associated cholestasis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0035777",
  "properties": {
    "xrefs": [
      "GARD:0022295",
      "MEDGEN:475934",
      "Orphanet:567983",
      "UMLS:C3274301",
      "icd11.foundation:1572634308"
    ],
    "synonyms": [
      "PNAC"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A rare hepatic disease characterized by intrahepatic cholestasis and deterioration of liver function in patients receiving parenteral nutrition for extended periods of time (signs may appear as early as within the first two weeks of initiation of parenteral nutrition). The condition commonly occurs in neonates and usually resolves with transition to enteral feeding, although severe cases may progress to liver fibrosis, cirrhosis, and portal hypertension."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3937,
      "label": "cholestasis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4900
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13580",
          "ICD9:576.2",
          "MEDGEN:925",
          "MESH:D002779",
          "SCTID:30144000",
          "UMLS:C0008370"
        ],
        "synonyms": [
          "obstruction of bile duct"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Impairment of the bile flow caused by obstruction within the liver, or outside the liver in the bile duct system."
      },
      "child_count": 5,
      "reference_id": "MONDO:0001751"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3937,
      "label": "cholestasis"
    }
  ]
}