{
  "id": 22944,
  "label": "ovarian Sertoli-Leydig cell tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0036595",
  "properties": {
    "xrefs": [
      "GARD:0027954",
      "MEDGEN:2038",
      "NCIT:C2880",
      "SCTID:254866007",
      "UMLS:C0003810"
    ],
    "synonyms": [
      "Sertoli-Leydig cell tumor of ovary",
      "Sertoli-Leydig cell tumor of the ovary",
      "Sertoli-Leydig cell tumour of ovary",
      "Sertoli-Leydig cell tumour of the ovary",
      "Sertoli-Leydig neoplasm of ovary",
      "Sertoli-Leydig neoplasm of the ovary",
      "androblastoma",
      "arrhenoblastoma",
      "ovarian Sertoli-Leydig cell neoplasm",
      "ovarian Sertoli-Leydig cell tumor"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A benign or malignant sex cord-stromal tumor arising from the ovary. It is characterized by the presence of neoplastic Leydig cells. Signs and symptoms include hirsutism, menorrhagia and metrorrhagia. It may be associated with trisomy 8."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 20204,
      "label": "ovarian sertoli-stromal cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027876",
          "MEDGEN:309515",
          "NCIT:C39966",
          "UMLS:C1518732"
        ],
        "synonyms": [
          "Ovarian Sertoli-Stromal Cell Tumor",
          "Ovarian Sertoli-Stromal Cell Tumour",
          "Ovarian Sertoli-Stromal Tumor",
          "Ovarian Sertoli-Stromal Tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A sex cord-stromal tumor that arises from the ovary and is composed entirely of, or in various combinations of, Sertoli cells, Leydig cells, and fibroblast-like cells."
      },
      "child_count": 1,
      "reference_id": "MONDO:0020807"
    }
  ],
  "children": [
    {
      "id": 19986,
      "label": "malignant Sertoli-Leydig cell tumor of ovary",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18316,
        22944
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0005495",
          "ICD9:239.5",
          "MEDGEN:1825991",
          "Orphanet:99916",
          "SCTID:237795006",
          "UMLS:C5574973"
        ],
        "synonyms": [
          "Androblastoma",
          "Arrhenoblastoma",
          "malignant ovarian Sertoli-Leydig cell tumor",
          "malignant ovarian Sertoli-Leydig cell tumour",
          "ovarian Sertoli-Leydig cell cancer",
          "ovarian Sertoli-Leydig cell tumor, malignant",
          "ovarian malignant Sertoli-Leydig cell tumor",
          "ovarian malignant Sertoli-Leydig cell tumour",
          "ovarian sertoli-Leydig cell tumor, malignant",
          "virilizing ovarian tumor",
          "virilizing ovarian tumour",
          "malignant Sertoli-Leydig cell tumor of the ovary",
          "malignant Sertoli-Leydig cell tumour of the ovary",
          "malignant ovarian sertoli-Leydig cell tumor",
          "malignant ovarian sertoli-Leydig cell tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Malignant Sertoli-Leydig cell tumor of ovary is a rare malignant sex cord stromal tumor of ovary occurring typically in young women and characterized by manifestations of androgen excess (hirsutism, hair loss, amenorrhea, or oligomenorrhea), when functional."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020542"
    }
  ],
  "roots": [
    {
      "id": 20204,
      "label": "ovarian sertoli-stromal cell tumor"
    }
  ]
}