{
  "id": 22946,
  "label": "spleen neoplasm",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0036696",
  "properties": {
    "xrefs": [
      "GARD:0007683",
      "MEDGEN:21292",
      "NCIT:C3383",
      "UMLS:C0037999"
    ],
    "synonyms": [
      "neoplasm of spleen",
      "spleen tumor",
      "spleen tumour",
      "splenic neoplasm",
      "tumor of spleen",
      "tumour of spleen"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A benign or malignant neoplasm that affects the spleen. Representative examples include hemangioma, lymphoma, splenic involvement by leukemia, and angiosarcoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4438,
      "label": "splenic disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7217,
        7447
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2529",
          "EFO:0009002",
          "ICD10CM:D73",
          "ICD9:289.50",
          "MEDGEN:21291",
          "MESH:D013158",
          "NCIT:C35823",
          "SCTID:51244008",
          "UMLS:C0037997"
        ],
        "synonyms": [
          "disease of spleen",
          "disease or disorder of spleen",
          "disorder of spleen",
          "spleen disease",
          "spleen disease or disorder",
          "spleen disorder",
          "splenic disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A disease involving the spleen."
      },
      "child_count": 16,
      "reference_id": "MONDO:0002332"
    },
    {
      "id": 4440,
      "label": "hematopoietic and lymphoid system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798,
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2531",
          "GARD:0023120",
          "MEDGEN:268180",
          "MESH:D019337",
          "NCIT:C35813",
          "SCTID:129154003",
          "UMLS:C1512393"
        ],
        "synonyms": [
          "haematopoietic neoplasm",
          "haematopoietic neoplasm (morphologic abnormality)",
          "hematologic neoplasm",
          "hematopoietic neoplasm",
          "hematopoietic neoplasm (morphologic abnormality)",
          "blood neoplasm (disease)",
          "blood tumor",
          "blood tumour",
          "haematological tumours",
          "haematopoietic and lymphoid system tumour",
          "haematopoietic system neoplasm",
          "haematopoietic system tumour",
          "haematopoietic tumours",
          "hematopoietic and lymphoid system neoplasm",
          "hematopoietic and lymphoid system tumor",
          "hematopoietic system neoplasm",
          "hematopoietic system tumor",
          "neoplasm of blood",
          "neoplasm of haematopoietic system",
          "neoplasm of hematopoietic system",
          "tumor of blood",
          "tumor of hematopoietic system",
          "tumour of blood",
          "tumour of haematopoietic system",
          "blood cancer",
          "haematopoietic cancer",
          "hematologic malignancy",
          "hematopoietic cancer",
          "malignant haematopoietic neoplasm (morphologic abnormality)",
          "malignant hematopoietic neoplasm (morphologic abnormality)",
          "hematologic cancer",
          "malignant haematopoietic neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Neoplasms of the hematopoietic system, including hematopoietic cell neoplasms (e.g. leukemias, lymphomas) and non-hematopoietic cell neoplasms that can affect the hematopoietic system (e.g. lymph node and splenic sarcomas). --2003"
      },
      "child_count": 18,
      "reference_id": "MONDO:0002334"
    }
  ],
  "children": [
    {
      "id": 7558,
      "label": "spleen cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3023,
        4587,
        22946
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:672",
          "EFO:0007491",
          "GARD:0024265",
          "ICD10CM:C26.1",
          "MEDGEN:102271",
          "MESH:D013160",
          "NCIT:C3539",
          "SCTID:127230005",
          "UMLS:C0153470",
          "icd11.foundation:347078862"
        ],
        "synonyms": [
          "spleen neoplasm",
          "splenic neoplasm",
          "cancer of spleen",
          "cancer of the spleen",
          "malignant neoplasm of spleen",
          "malignant neoplasm of the spleen",
          "malignant spleen neoplasm",
          "malignant splenic neoplasm",
          "malignant splenic tumor",
          "malignant splenic tumour",
          "malignant tumor of spleen",
          "malignant tumor of the spleen",
          "malignant tumour of the spleen",
          "spleen cancer",
          "splenic cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the spleen"
      },
      "child_count": 15,
      "reference_id": "MONDO:0005966"
    },
    {
      "id": 17884,
      "label": "marginal zone lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17874,
        22946
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050748",
          "EFO:1000630",
          "GARD:0013237",
          "ICDO:9699/3",
          "MEDGEN:277950",
          "NCIT:C4341",
          "ONCOTREE:MZL",
          "Orphanet:300912",
          "SCTID:447100004",
          "UMLS:C1367654"
        ],
        "synonyms": [
          "MZBCL",
          "MZL",
          "lymphoma of marginal zone B cell",
          "marginal zone B cell lymphoma",
          "marginal zone B-cell lymphoma",
          "marginal zone lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A usually indolent mature B-cell lymphoma, arising from the marginal zone of lymphoid tissues. It is characterized by the presence of small to medium sized atypical lymphocytes. It comprises three entities, according to the anatomic sites involved: extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue, which affects extranodal sites (most often stomach, lung, skin, and ocular adnexa); nodal marginal zone B-cell lymphoma, which affects lymph nodes without evidence of extranodal disease; and splenic marginal zone B-cell lymphoma, which affects the spleen and splenic hilar lymph nodes, bone marrow, and often the peripheral blood."
      },
      "child_count": 8,
      "reference_id": "MONDO:0017604"
    },
    {
      "id": 20621,
      "label": "benign neoplasm of spleen",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3035,
        22946
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025325",
          "ICD9:211.9",
          "MEDGEN:146355",
          "NCIT:C4902",
          "SCTID:92408009",
          "UMLS:C0686615"
        ],
        "synonyms": [
          "benign neoplasm of the spleen",
          "benign splenic neoplasm",
          "spleen benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the spleen."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021500"
    }
  ],
  "roots": [
    {
      "id": 4438,
      "label": "splenic disorder"
    },
    {
      "id": 4440,
      "label": "hematopoietic and lymphoid system neoplasm"
    }
  ]
}