{
  "id": 22953,
  "label": "benign Leydig cell tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0036990",
  "properties": {
    "xrefs": [
      "ICDO:8650/0",
      "MEDGEN:83142",
      "NCIT:C4212",
      "UMLS:C0334409"
    ],
    "synonyms": [
      "Leydig cell tumor, benign",
      "adenoma, interstitial",
      "benign Leydig cell neoplasm",
      "benign Leydig cell tumor",
      "benign interstitial cell neoplasm",
      "benign interstitial cell tumor",
      "benign interstitial cell tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A Leydig cell tumor which does not recur or metastasize. Morphologically, there is no evidence of cellular atypia, increased mitotic activity, necrosis, or vascular invasion."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7810,
      "label": "Leydig cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7639
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2696",
          "EFO:1000321",
          "ICDO:8650/1",
          "MEDGEN:9747",
          "MESH:D007984",
          "NCIT:C3188",
          "UMLS:C0023601"
        ],
        "synonyms": [
          "Leydig cell neoplasm",
          "Leydig cell tumor",
          "interstitial cell neoplasm",
          "interstitial cell tumor",
          "interstitial cell tumour",
          "Leydig cell tumor, undetermined"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A sex cord-stromal tumor occurring in the testis and rarely in the ovary. It is predominantly or completely composed of Leydig cells which may contain crystals of Reinke. In males it usually presents as a painless testicular enlargement and it may be associated with gynecomastia and decreased libido. The majority of the cases have a benign clinical course. Approximately 10% of the cases have a malignant clinical course and metastasize. In females it may be associated with androgenic manifestations and it follows a benign clinical course."
      },
      "child_count": 3,
      "reference_id": "MONDO:0006266"
    },
    {
      "id": 21634,
      "label": "sex cord-stromal benign neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2882,
        7639
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080368"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A reproductive organ benign neoplasm that arises in the ovary or testis and that is composed of granulosa cells, Leydig cells, Sertoli cells, and/or fibroblasts."
      },
      "child_count": 6,
      "reference_id": "MONDO:0024988"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7810,
      "label": "Leydig cell tumor"
    },
    {
      "id": 21634,
      "label": "sex cord-stromal benign neoplasm"
    }
  ]
}