{
  "id": 22961,
  "label": "ovarian thecoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0037253",
  "properties": {
    "xrefs": [
      "GARD:0027955",
      "MEDGEN:364155",
      "NCIT:C66989",
      "SCTID:254864005",
      "UMLS:C1882229"
    ],
    "synonyms": [
      "ovarian theca cell neoplasm",
      "ovarian theca cell tumor",
      "ovarian theca cell tumour",
      "ovarian thecoma",
      "ovary thecoma",
      "theca cell neoplasm of ovary",
      "theca cell neoplasm of the ovary",
      "theca cell tumor of ovary",
      "theca cell tumor of the ovary",
      "theca cell tumour of ovary",
      "theca cell tumour of the ovary",
      "thecoma of ovary",
      "thecoma of the ovary"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A stromal tumor that arises from the ovary and is characterized by the presence of cells that contain lipid and resemble theca cells. The vast majority of cases are benign."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 20709,
      "label": "ovarian sex cord-stromal tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7639,
        20309
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080369",
          "GARD:0012285",
          "MEDGEN:154644",
          "NCIT:C4862",
          "ONCOTREE:SCST",
          "UMLS:C0600113"
        ],
        "synonyms": [
          "Sex cord-stromal neoplasm of ovary",
          "Sex cord-stromal neoplasm of the ovary",
          "Sex cord-stromal tumor of ovary",
          "Sex cord-stromal tumor of the ovary",
          "Sex cord-stromal tumour of ovary",
          "Sex cord-stromal tumour of the ovary",
          "ovarian Sex cord-stromal neoplasm",
          "ovarian Sex cord-stromal tumor",
          "ovarian Sex cord-stromal tumour",
          "ovary sex cord-stromal tumor",
          "ovary sex cord-stromal tumour",
          "sex cord-stromal tumor of ovary",
          "sex cord-stromal tumour of ovary",
          "ovarian sex cord tumor with annular tubules",
          "ovarian sex cord tumour with annular tubules",
          "sex cord stromal tumor",
          "sex cord stromal tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that arises from the ovary and is composed of granulosa cells, Sertoli cells, Leydig cells, theca cells, and fibroblasts. Representative examples include thecoma, fibroma, Sertoli cell tumor, and granulosa cell tumor."
      },
      "child_count": 12,
      "reference_id": "MONDO:0021657"
    },
    {
      "id": 22960,
      "label": "thecoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7639
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8600/0",
          "MEDGEN:21505",
          "MESH:D013798",
          "NCIT:C3405",
          "UMLS:C0039747"
        ],
        "synonyms": [
          "thecoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An ovarian or testicular stromal tumor characterized by the presence of lipid-rich neoplastic spindle cells. In females, uterine bleeding is the most common symptom. A minority of post-menopausal women with thecoma have an associated endometrial adenocarcinoma or rarely a malignant mixed mullerian tumor or endometrial stromal sarcoma. Rare cases with nuclear atypia and mitotic activity may metastasize. In males, thecomas are rare and they usually present as slow growing, sometimes painful masses. Metastases have not been reported."
      },
      "child_count": 2,
      "reference_id": "MONDO:0037252"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 20709,
      "label": "ovarian sex cord-stromal tumor"
    },
    {
      "id": 22960,
      "label": "thecoma"
    }
  ]
}