{
  "id": 22972,
  "label": "endometrioid stromal and related neoplasms",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0037742",
  "properties": {
    "xrefs": [
      "MEDGEN:925400",
      "NCIT:C8384",
      "UMLS:C4287868"
    ],
    "synonyms": [
      "endometrioid stromal and related neoplasms",
      "endometrioid stromal and related tumors",
      "endometrioid stromal and related tumours"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A category of mesenchymal gynecologic neoplasms. It includes endometrial stromal nodule, endometrioid stromal sarcoma, and undifferentiated sarcoma. Endometrial stromal nodule has been described in the uterine corpus only. Histologically, it is characterized by the lack of infiltration of the surrounding tissues. Endometrioid stromal sarcoma affects the uterine corpus, and rarely, the ovaries, cervix, and vagina. In the uterine corpus it is classified as low grade or high grade endometrial stromal sarcoma. In the remainder of the anatomic sites it is classified as low grade endometrioid stromal sarcoma. Undifferentiated sarcoma was previously also known as high grade endometrial stromal sarcoma. In 2014, high grade endometrial stromal sarcoma was reclassified and is currently considered a distinct and rare neoplasm that affects the uterine corpus only. It appears to have a prognosis that falls between low grade endometrial stromal sarcoma and undifferentiated sarcoma. The latter affects the uterine corpus and rarely the remainder of the anatomic sites."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 20384,
      "label": "female reproductive system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4379,
        7638
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:9004",
          "MESH:D005833",
          "NCIT:C3053",
          "UMLS:C0017416"
        ],
        "synonyms": [
          "female reproductive organ neoplasm (disease)",
          "female reproductive organ tumor",
          "female reproductive organ tumour",
          "female reproductive system neoplasm",
          "female reproductive system neoplasm (disease)",
          "female reproductive system tumor",
          "female reproductive system tumour",
          "gynecologic neoplasm",
          "gynecologic tumor",
          "gynecologic tumour",
          "neoplasm of female reproductive organ",
          "neoplasm of female reproductive system",
          "neoplasm of the female reproductive system",
          "tumor of female reproductive system",
          "tumor of the female reproductive system",
          "tumour of female reproductive system",
          "tumour of the female reproductive system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign, precancerous, or malignant neoplasm that affects the female reproductive system. Representative examples include uterine corpus leiomyoma, endocervical polyp, ovarian carcinoma, cervical carcinoma, and endometrial carcinoma."
      },
      "child_count": 22,
      "reference_id": "MONDO:0021148"
    }
  ],
  "children": [
    {
      "id": 5252,
      "label": "ovarian endometrioid stromal and related neoplasms",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20309,
        22972
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5169",
          "MEDGEN:926076",
          "NCIT:C40065",
          "UMLS:C4288544"
        ],
        "synonyms": [
          "endometrioid stromal and related neoplasms of ovary",
          "ovarian endometrioid stromal and related neoplasms",
          "ovary endometrioid stromal and related neoplasms",
          "ovarian endometrioid stromal sarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A category of rare neoplasms that arise from the ovary. It includes low grade endometrioid stromal sarcoma and undifferentiated sarcoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003312"
    },
    {
      "id": 5254,
      "label": "endometrioid stromal and related neoplasms of the vagina",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20294,
        22972
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5171",
          "MEDGEN:927117",
          "NCIT:C40269",
          "UMLS:C4289585"
        ],
        "synonyms": [
          "endometrioid stromal and related neoplasms of the vagina",
          "endometrioid stromal and related neoplasms of vagina",
          "endometrioid stromal and related tumors of the vagina",
          "endometrioid stromal and related tumours of the vagina",
          "vagina endometrioid stromal and related neoplasms",
          "vaginal endometrial stromal tumor",
          "vaginal endometrial stromal tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A category of rare neoplasms that arise from the vagina. It includes low grade endometrioid stromal sarcoma and undifferentiated sarcoma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003314"
    }
  ],
  "roots": [
    {
      "id": 20384,
      "label": "female reproductive system neoplasm"
    }
  ]
}